Enzymes and Inhibitors
Enzo Life Sciences Ac-YVAD-AFC (10mg)
Substrate for caspase-1 and -4. Fluorogenic substrate for caspase-1 and -4. Alternative name: Caspase 1 substrate (fluorogenic), Caspase 4 substrate (fluorogenic). Formula: C33H36F3N5O10. MW: 719.7. Purity: ≥97% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO. Long Term Storage: -20°C. Use/Stability: Solid product is stable for 1 year in desiccator when stored at room temperature. Stock solutions are stable for 6 – 8 months when stored at –20°C. Keep sealed after removing from the freezer until its temperature equilibrates with room temperature. Handling: Keep cool and dry.
Abcam 4-Trifluoromethylumbelliferyl oleate, 10MG
MW 494.6 Da. Fluorescent lipase substrate. Releases highly fluorescent 4-trifluoromethylumbelliferone upon hydrolysis. 4-trifluoromethylumbelliferone is insensitive to pH making it suitable for use in food analysis.
The product is subject to the following: Abcam Restricted Use Statement
Seracare Life Sciences Inc 4CN 2-C MEMB HRP SUBSTRATE
An ideal alternative to other, more sensitive substrates where background is a problem. 4 CN (4-chloro-1-napthol) produces a precipitate at the reaction site in the presence of peroxidase-labeled conjugates. It is optimized for use in membrane assays and dot blots. 2-component format, simply mix and use.
Medchemexpress LLC HER2/CD340 Mouse H 10ug
The HER2/CD340 protein is a multifunctional tyrosine kinase that is a component of the neuregulin receptor complex and regulates microtubule dynamics Activated HER2/CD340 triggers the MEMO1-RHOA-DIAPH1 pathway inhibits GSK3B on the cell membrane and promotes the binding of APC and CLASP2 which is critical for microtubule stability HER2/CD340 Protein Mouse (HEK293 N-His) is the recombinant mouse-derived HER2/CD340 protein expressed by HEK293 with N-His labeled tag
Sigma Aldrich Fine Chemicals Biosciences Cytidine 2′:3′-cyclic monophosphate monosodium salt | 15718-51-1 | MFCD00135656 | 250 mg
Cytidine 2′:3′-cyclic monophosphate monosodium salt | Purity: ≥95% | Mol Wt: 327.16 | 15718-51-1 | MFCD00135656 | 250 mg
Cayman Chemical Abl Substrate Peptide triflu
A peptide substrate for Abl; selectively phosphorylated by Abl over c-Src kinase at 20 µM; has been used to quantify Abl kinase activity in vitro
STA PHARMACEUTICAL US LLC Fmoc-D-2-Nitrophe | 25 g | CAS 478183-70-9 | MDL MFCD01317714
Fmoc-D-2-Nitrophe is a Amino Acid reagent (Subcategory: Phe) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 478183-70-9
- MDL: MFCD01317714
- InChIKey: KVLRWXBYPKSBFY-OAQYLSRUSA-N
- Molecular Weight: 432.432
- Molecular Formula: C24H20N2O6
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-nitrophenyl)propanoic acid
- SMILES: O=C([C@@H](CC1=CC=CC=C1[N+]([O-])=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)O
CPC Scientific DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS (trifluoroacetate salt) 0.5MG
TACE FRET substrate I that is derived from the cleavage sequence of pro-TNFa recognized by the TNFa-cleaving enzyme (TACE). TNFa is presumably shed from cell membranes by TNFa-cleaving enzyme (TACE). Incubation of the TACE substrate with recombinant human TACE gives a specific cleavage to restore the quenched fluorescence. The substrate is widely used to screen inhibitors of TNF-convertase.ONE-LETTER SEQUENCE: Dabcyl-LAQAVRSSSR-EDANSMOLECULAR FORMULA: C70H104N22O18S1MOLECULAR WEIGHT:1573.80STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [396716-14-6], SYNONYMS: DABCYL-TNF--EDANS (-4 to +6) (human)RESEARCH AREA: ApoptosisREFERENCES: A.J. H.Gearing et al., Nature , 370, 555 (1994); K.M. Mohler et al., Nature , 370, 218 (1994); Becker BF, et al.Biol Chem 383, 1821-6 (2002); Mohler KM, et al., Nature 370, 218-20. (1994);
Research Products International Corp 4-NITROPHENYL-A-D-MANNOPYRANOSIDE 500MG
Spectrophotometric substrate for detection of α-Mannosidase.
Free PNP: <200ppm
Abcam Magenta-Gal, Chromogenic beta-galactosidase substrate, 500MG
MW 408.63 g/mol. Chromogenic substrate for β-galactosidase producing a red or magenta insoluble product. Used to determine the presence or absence of a cloned DNA insert in bacteria growing on agar plates. Designed to replace X-Gal in blue-white selection of recombinant bacterial colonies with the lac+ phenotype. Lac+ colonies grown in the presence of Magenta-Gal turn an intense red color, allowing for easy differentiation between lac+ and lac- colonies.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Her2/CD340 protein, rat (HEK293, His) | >95.0% | 5 UG
Recombinant rat HER2/CD340 protein expressed in HEK293 cells with a C-terminal His tag. Supplied as a purified ectodomain suitable for biochemical assays, antibody development, receptor binding studies, and structural or biophysical analysis. Molecular weight is approximately 91 kDa and purity is greater than 95% by reducing SDS-PAGE.
- Recombinant rat HER2 protein produced in HEK293 expression system.
- C-terminal His tag for efficient purification.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Approximate molecular weight 91 kDa.
- Suitable for biochemical assays, antibody generation, and binding studies.
- Available in small research quantities (for example, 5 μg).
Vector Laboratories VECTOR Blue Alkaline Phosphatase (AP) Substrate Kit 200 ml
VECTOR Blue Alkaline Phosphatase (AP) Substrate Kit produces a blue, heat-stable reaction product. This chromogen can be used singly or in combination with other alkaline phosphatase or peroxidase substrates for multiple label applications. Sections stained with the VECTOR Blue substrate can be dehydrated, cleared, and permanently mounted; however, non-xylene clearing agents and non-xylene based mounting media (such as VectaMount) must be used because the reaction product is soluble in xylene. VECTOR Blue can also be used on blots in applications such as ELISPOT, singly or in combination with a peroxidase substrate such as AEC. The stock solutions in this kit are provided in convenient dropper bottles, with sufficient volume for 200 ml working solution.
Enzo Life Sciences NEDD8-AMC (25 µg)
NEDD8-AMC is a fluorogenic substrate for deNEDDylating enzymes, including NEDP1 and UCH-L3. It is a particularly useful reagent for the study of deNEDDylating activity where detection sensitivity or continuous monitoring of activity is essential. NEDD8-AMC is a fluorogenic substrate for deNEDDylating enzymes, including NEDP1 and UCH-L3. It is a particularly useful reagent for the study of deNEDDylating activity where detection sensitivity or continuous monitoring of activity is essential. Concentration: 1 mg/ml. Purity: ≥95% (HPLC). Formulation: Solution in DMSO. Source: Produced in E. coli. Long Term Storage: -80°C.
Enzo Life Sciences AEC peroxidase substrate kit (300ml)
The AEC Peroxidase Substrate Kit contains reagents for visualization of peroxidase reactions using Aminoethylcarbazole (AEC). In the presence of H2O2, peroxidases catalyze the oxidation of AEC into a brick red precipitate. The supplied reagents are sufficient for preparation of 300 ml of ready-to-use color reaction mixture. Applications: Colorimetric detection .