Enzymes and Inhibitors
Medchemexpress LLC Boc-Gly-Lys-Arg-AMC | 109358-48-7 | 616.71 | 10 MG
Boc-Gly-Lys-Arg-AMC is a polypeptide used in peptide screening, a research tool that identifies active peptides primarily through immunoassay. This product is suitable for protein interaction studies, functional analysis, and epitope screening, particularly in agent research and development. It is intended for research use only.
- Polypeptide for peptide screening
- Used in protein interaction studies
- Suitable for functional analysis
- Ideal for epitope screening
- Research use only
- Chemical formula: C29H44N8O7
- Sequence: {Boc-Gly}-Lys-{Arg-AMC}
- Molecular weight: 616.71
Medchemexpress LLC MBP MAPK Substrate | 138028-00-9 | 99.6% | 967.09 | 10 MG
MBP MAPK Substrate is utilized as an exogenous substrate for MAPK.
- Sequence: Ala-Pro-Arg-Thr-Pro-Gly-Gly-Arg-Arg
- Solubility: H2O
- Powder storage: -80°C for 2 years, -20°C for 1 year (sealed storage, away from moisture)
- Solvent storage: -80°C for 6 months, -20°C for 1 month (sealed storage, away from moisture)
Cayman Chemical Ac-DEVD-AMC 1mg
A fluorogenic substrate that can be cleaved specifically by caspase-3
Medchemexpress LLC Boc-Gly-Lys-Arg-AMC | 109358-48-7 | 616.71 | 5 MG
Boc-Gly-Lys-Arg-AMC is a polypeptide identified through peptide screening. This research tool primarily uses immunoassay to pool active peptides. It can be utilized for protein interaction, functional analysis, and epitope screening, especially in agent research and development. This product is for research use only.
- Identified through peptide screening
- Primarily uses immunoassay to pool active peptides
- Utilized for protein interaction
- Suitable for functional analysis
- Can be used for epitope screening
- Aids in agent research and development
- For research use only
Surmodics Inc TMB Super Sensitive One Component HRP Microwell Substrate, 100mL
The BioFX™ one component 3,3’,5,5’-tetramethylbenzidine (TMB) substrate is supplied in a ready-to-use solution. Peroxidase reacts with the TMB substrate solution to produce a soluble blue reaction product that can be read at 370 nm or 620-650 nm for ELISA applications. Stop solutions can be added to prevent further color development and reading the absorbance values at the desired wavelengths.
Abcam 2-Chloro-4-nitrophenyl-ß-D-cellobioside, 25MG
MW 497.8 Da, Purity >95%. Chromogenic substrate for cellulase activity. Suitable for kinetic characterisation of cellulases. Useful for biofuels research to measure cellulase activity for optimum ethanol production.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC HER2/CD340 Human S 5ug | 5ug
The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics Upon activation it triggers the MEMO1-RHOA-DIAPH1 pathway inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization HER2/CD340 Protein Human (S310Y HEK293 His) is the recombinant human-derived HER2/CD340 protein expressed by HEK293 with C-10 His labeled tag and S310Y mutation
![Alkali Scientific D Luciferin Potassium Salt [4,5 Dihydro 2 (6 hydroxy 2 benzothiazolyl) 4 thiazolecarboxylic acid, potassium salt], 3 Grams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660940.jpg-250.jpg)
Alkali Scientific D Luciferin Potassium Salt [4,5 Dihydro 2 (6 hydroxy 2 benzothiazolyl) 4 thiazolecarboxylic acid, potassium salt], 3 Grams
Luciferin potassium salt is a luminescent substrate used in bioluminescence assays. The substrate is oxidized by luciferase enzymes to produce light, making it ideal for cell assays, enzyme activity detection, and ATP measurements. This 3g quantity is highly concentrated and suitable for a variety of applications, including gene expression studies, cellular viability assays, and metabolic activity analysis. The bioluminescent reaction is highly sensitive and provides rapid results, allowing researchers to quantify enzyme activity and monitor cellular processes in real time. Luciferin is commonly used in biological research and diagnostic assays, offering a powerful tool for detecting low levels of biological activity.
Medchemexpress LLC N-α-CBZ-L-arginine 7-amido-4-methylcoumarin hydrochloride | 70375-22-3 | MFCD00039019 | 99.2% | 501.96 g/mol | C24H28ClN5O5 | 5 MG
Z-Arg-AMC hydrochloride (CAS 70375-22-3) is a fluorogenic peptide substrate that releases 7-amino-4-methylcoumarin (AMC) upon enzymatic cleavage, enabling fluorescence-based assays to measure protease activity such as trypsin and papain. The compound is supplied as a white to off-white solid with high purity and is typically stored frozen to preserve stability.
- Suitable for measuring trypsin and papain activity in fluorescence assays (Ex/Em 390/480 nm; alternative 355/460 nm).
- High purity (99.2%) for reliable assay results.
- Releases AMC fluorophore for sensitive detection of proteolytic activity.
- White to off-white solid, convenient for weighing and formulation.
- Stable under sealed storage at -20 °C; protect from moisture and light.
Medchemexpress LLC EGFR/HER2-IN-9 | 1637253-79-2 | C25H25ClFN5O4 | 5 MG
EGFR/HER2-IN-9 (Compound 1) is an EGFR and HER2 inhibitor for research use only.
- Inhibits EGFR with an IC50 of 3.2 nM
- Inhibits EGFR T790M with an IC50 of 8.3 nM
- Inhibits HER2 with an IC50 of 14 nM
![AdipoGen Ac-Ala-Asn-Trp-AMC [Ac-ANW-AMC], 2 mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501490625.PNG-250.jpg)
AdipoGen Ac-Ala-Asn-Trp-AMC [Ac-ANW-AMC], 2 mg
Ac-Ala-Asn-Trp-AMC [Ac-ANW-AMC] (2 mg), AdipoGen Life Sciences. Chemical. Formula: C30H32N6O7. MW: 588.6. Synthetic. Ac-ANW-AMC is a fluorogenic peptide substrate for measuring chymotrypsin-like activity of the immunoproteasome. Hydrolysis of this substrate by the beta5i-subunit of the immunoproteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This substrate is specific to the immunoproteasome and is not hydrolyzed efficiently by the constitutive proteasome.
Cayman Chemical G6PDH Substrate 1ea
A PARP1 and PARP2 inhibitor (IC50s 50s 1-14.1 nM) inhibits the proliferation of Capan-1 cells (IC50 0.1 nM) as well as talazoparib- or olaparib-resistant Capan-1 cells (IC50s 1.13 and 0.89 nM respectively) inhibits the proliferation of BRCA1 mutant HCC1937 breast cancer cells (IC50 4.54 nM) reduces tumor growth in an olaparib-resistant MDA-MB-436 breast cancer mouse xenograft model at 12.5 and 25 mg/kg
Sino Biological Peptide Substrates: Chktide
The Chktide peptide sequence (KKKVSRSGLYRSPSMPENLNRPR) is based on the human CDC25C protein isoform A (amino acid 205-225).