Enzymes and Inhibitors
New England Biolabs, Inc. MspI – 5000 units
A restriction endonuclease that recognizes the sequence C^CG_G.
Cayman Chemical Oleoyl EthnolamIde 50mg
An acid-sensitive fluorescent probe upon protonation it displays a shift in emission maxima from 410 nm to 510 nm upon excitation at 157 nm has been commonly used in photolithography
Supply Solutions Sigma Aldrich - L-LDH, (rabbit muscle), 25 mg * Third Party Item
Sigma Aldrich - L-LDH, (rabbit muscle), 25 mg * Third Party Item
New England Biolabs, Inc. HphI – 5000 units
A restriction endonuclease that recognizes the sequence GGTGANNNNNNN_N^.
New England Biolabs, Inc. HpyAV – 500 units
A restriction endonuclease that recognizes the sequence CCTTCNNNNN_N^.
Cayman Chemical COX1 ovne 5kU
An analytical reference standard categorized as a precursor in the synthesis of cathinones intended for research and forensic applications
New England Biolabs, Inc. AvaII – 10000 units
A restriction endonuclease that recognizes the sequence G^GWC_C.
New England Biolabs, Inc. PNGase A – 750 units
PNGase A cleaves between the innermost GlcNAc and asparagine residues of high mannose, hybrid, and short complex oligosaccharides such as those found in plant and insect cells from N-linked glycoproteins and glycopeptides. PNGase A differs from PNGase F in that it cleaves N-linked glycans with or without (1,3)-linked core fucose residues.
New England Biolabs, Inc. BstEII – 2000 units
A restriction endonuclease that recognizes the sequence G^GTNAC_C.
New England Biolabs, Inc. SalI – 10000 units
A restriction endonuclease that recognizes the sequence G^TCGA_C.
Cayman Chemical SPHK Substrate 1ea
A PD-1/PD-L1 interaction inhibitor (IC50 6.3 nM) increases T cell proliferation in a PD-L1-overexpressing CT26 colon cancer cell and T cell co-culture at 20 nM promotes T cell infiltration into an in vitro PD-L1-overexpressing murine Lewis lung carcinoma tumor matrix at 20 and 80 nM reduces tumor growth and promotes CD8 and CD4 T cell tumor infiltration in a PD-L1-overexpressing murine Lewis lung carcinoma model at 20 mg/kg
Cayman Chemical MPO ChlorInatIon Substrate 1ea
A Clk1 Clk2 and Clk4 inhibitor (IC50s 8 20 and 12 nM respectively) selective for these kinases over Clk3 (IC50 >3000 nM) as well as DYRK1A DYRK1B DYRK2 HIPK1 and HIPK3 (IC50s 213 956 1309 187 and 159 nM respectively) but does inhibit HIPK2 (IC50 23 nM)
New England Biolabs, Inc. NcoI – 5000 units
A restriction endonuclease that recognizes the sequence C^CATG_G.
New England Biolabs, Inc. NciI – 10000 units
A restriction endonuclease that recognizes the sequence CC^S_GG.