Custom Peptides
Cayman Chemical 10-Pyren-PC 10mg
10-Pyrene-PC is a substrate for all PLA2s with the exception of cPLA2 and PAF-AH.{5681} Upon phospholipid hydrolysis, 10-pyrenyldecanoic acid is produced from 10-pyrene-PC. The monomeric 10-pyrenyldecanoic acid exhibits fluorescence (excitation 345 nm, emission 395 nm), allowing quantitation of phospholipase activity.{3839}
Cayman Chemical Tocotrienol 10mg
An isomer of Vitamin E that has less potent antioxidant properties than α-tocotrienol
Cayman Chemical ngelIs Salt 10mg
A classical nitroxyl (NO-) donor; dissociates in a pH-dependent, first order process with a half-life of 2.3 minutes at 37°C, pH 7.4, to liberate 0.54 moles for NO per mole of parent compound
Cayman Chemical R-nItro-BlebbIstatIn 10mg
A more stable form of (+)-blebbistatin, the inactive form of blebbistatin; has the same stereochemistry as the inactive (+)-blebbistatin enantiomer
Cayman Chemical StearIdonIc AcId 10mg
Stearidonic acid is an 18-carbon, ω-3 fatty acid which is a dietary precursor to EPA and DHA. Stearidonic acid is present in small amounts in seed oils, especially black currant seed oil.
Cayman Chemical ZLN005hydrochlorIde 10mg
A small molecule that stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM; 15 mg/kg/day administered to diabetic db/db mice improved glucose tolerance, pyruvate tolerance, and insulin sensitivity
Cayman Chemical ArachIdonyl-L-carnItInchl 10mg
An acylcarnitine formed from carnitine conjugated to arachidonic acid; may be useful as a marker of mitochondrial dysfunction
Cayman Chemical 7hydroycoumarInyl AracHDn 10mg
A fluorogenic substrate for cPLA2; hydrolysis results in the release of the fluorescent compound 7-hydroxycoumarin (ex 335 nm, em 450 nm)
Cayman Chemical N 8ZHeptadecen1ylO 3p 10mg
A synthetic macamide that irreversibly inhibits FAAH with an IC50 value of 0.153 µM
Cayman Chemical mthyl AracHDnyl Fluoropho 10mg
An inhibitor of MAGL and FAAH (IC50s = 26.3 and 0.33 nM, respectively); irreversible inhibitor of cPLA2, as well as iPLA2 (IC50 = 500 nM); inhibits A23187-induced arachidonic acid release from human platelets (IC50 = 600 nM)
Cayman Chemical 2Omethyl PAF C18hydrAT 10mg
A synthetic PAF analog which contains an ether-linked methyl group at the sn-2 position; decreases plasma membrane fluidity, inhibits tumor cell invasiveness, and causes the release of large quantities of NO by a pathway involving activation of NOS
Cayman Chemical SalvInolIc AcId B 10mg
An antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties
Cayman Chemical 2ImIno4methylpIperIdIna 10mg
2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC50 values of 0.1, 1.1, and 0.2 µM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 µM.{5579}
Cayman Chemical S-EIcosapentaenyl-2-Hy 10mg
A homolog of EPEA, characterized by the addition of an (S)-β-methyl group at the terminal ethanolamine carbon