Custom Peptides
Cayman Chemical 1 3DIpalmItol2ElaIdol Gl 10mg
A triacylglycerol; has been synthesized as a partially hydrogenated confectionery fat; when used as 10% of the fat component in cocoa butter, it promotes the conversion of low-melting polymorphic forms of cocoa butter-PEP mixtures to high-melting polymorphic forms
Cayman Chemical TelocInobufagIn 10mg
A cardiotonic steroid with diverse biological activities; inhibits human kidney Na+/K+-ATPase (IC50 = 44.2 nM); increases contraction force in isolated frog ventricle strips by 30.2% at 9.9 μg/ml; cytotoxic to HL-60, HCT8, SF295, MDA-MB-435 cancer cells, and human peripheral blood lymphocytes (IC50s = 0.06, 0.06, 0.03, 0.11, and 0.05 μM, respectively); active against E. coli and S. aureus (MICs = 64 and 128 μg/ml, respectively)
Cayman Chemical Fludarabn 10mg
An intermediate active metabolite of fludarabine phosphate; inhibits the proliferation of RPMI-8226, MM.1S, and MM.1R multiple myeloma cells (IC50s = 1.54, 13.48, and 33.79 µM, respectively); increases Bax levels and decreases Bid, XIAP, and survivin levels, in RPMI-8226 cells at 2 UG/ml; an inhibitor of SARS-CoV-2 RdRp (EC50 = 1.06 µM); completely inhibits DNA synthesis in an SA-NH murine sarcoma model at 200 mg/kg; reduces tumor growth in an RPMI-8226 mouse xenograft model at 40 mg/kg; reduces tumor growth in an L1210 murine leukemia model
Cayman Chemical 6-MAPBhydrochlorIde 10mg
An analytical reference standard categorized as a benzofuran; intended for research and forensic applications
Cayman Chemical EpIoxytetracyclIn 10mg
A degradation product of oxytetracycline; has been found in swine manure compost and wastewater; considered a pollutant
Cayman Chemical TrImetazIdInd8hydrochLRI 10mg
An internal standard for the quantification of trimetazidine by GC- or LC-MS
Cayman Chemical CH 275acetate 10mg
A cyclic peptide agonist of SST1 (IC50 = 30.9 nM for the human receptor); selective for SST1 over SST2, SST3, SST4, and SST5 (IC50s = >10,000, 345, >1,000, and >10,000 nM, respectively, for the human receptors); inhibits basal growth hormone secretion from primary mouse pituitary cells at 500 nM; inhibits glucose-induced increases in electrical activity without inducing membrane hyperpolarization in a whole-cell patch-clamp assay using MIN6 pancreatic β-cells at 100 nM
Cayman Chemical 3-ChlorogentIsyl Alcohol 10mg
A phenol and microbial metabolite with diverse biological activities; scavenges DPPH radicals in a cell-free assay (IC50 = 1 µM); acitve against MRSA (MIC = 50 UG/ml); active against 13 Gram-positive and Gram-negative bacteria at 50 UG/disc; has concentration-dependent antifouling activity against barnacle cyprids in the conventional submerged assay using polystyrene plates in a concentration-dependent manner; induces apoptosis and cell cycle arrest at the S phase in HeLa cancer cells at 50 µM; induces ssDNA breaks in a comet assay using HeLa cells at 35 µM
Cayman Chemical Solamargn 10mg
A glycoalkaloid with anticancer activity; decreases viability of H1650, H1975, PC-9, A549, and H1299 NSCLC cells at 6 µM; reduces tumor growth in an A549 mouse xenograft model at 8 mg/kg per day
Cayman Chemical CNDAChydrochlorIde 10mg
A nucleoside derivative and an active metabolite of sapacitabine; induces chromosomal aberrations in UV41 cells lacking XPF at 1 µM; cytotoxic to BRCA1-/- UWB1.289 and BRCA2-/- PEO1 cells (IC50s = 9.9 and 10.2 nM, respectively)
Cayman Chemical PAR21-6mouserat 10mg
A peptide agonist of PAR2; induces relaxation in precontracted rat arteries; inhibits keratinocyte growth in the presence and absence of growth factors; inhibits LPS-induced pulmonary neutrophil influx and increases in MMP-2 activity in mice
Cayman Chemical 1 2DIstearoyl3PalmItoylra 10mg
A triacylglycerol; has been found in cocoa butter, lard, and cod liver oil