Custom Peptides
Cayman Chemical AmInoethylsPropIonIc AcId 10mg
A flavanone glucoside active against H pylori at 0 5 mM scavenges DPPH radicals (IC50 2 04 mM) and inhibits the activity of intestinal maltase and HMG-CoA reductase (Kis 1800 and 9 8 UM respectively for the human enzymes) in cell-free assays prevents decreases in bone mineral density in the femur of ovariectomized rats at 2 5 and 5 g/kg diet
Cayman Chemical 3-DeoxyurIdIn 10mg
An aglcyone form of the antitumor antibiotic daunorubicin has been used as a starting material in the synthesis of anticancer agents
Cayman Chemical 4-Alylcatechol 10mg
An aglcyone form of the antitumor antibiotic daunorubicin has been used as a starting material in the synthesis of anticancer agents
Cayman Chemical RhamnopterIn 10mg
Immunogen BSA-conjugated N6-methyladenosine Host Rabbit Species Reactivity Species independent Cross Reactivity ( ) m6A-RNA m6A-DNA (-) Non-methylated adenosine Applications DB ELISA MeRIP
Cayman Chemical 6 7 4-TrIhydroxyIsoflavon 10mg
An inhibitor of a-glucosidases and glycoprotein processing inhibits sucrase and maltase (IC50s 0 068 and 0 46 Ug/ml respectively) and R niveus glucoamylase (IC50s 1 6 and 4 7 Ug/ml with starch or maltose as substrates respectively) selective for these enzymes overBglucosidase (IC50 363 Ug/ml) inhibits HPAI oligosaccharide processing in HPAI-infected chicken embryo cells inhibits postprandial increases in blood glucose levels in sucrose-loaded rats (ED50 5 8 mg/kg)
Cayman Chemical AlexamorelIntrIfluoROCTAt 10mg
An aminoglycoside antibiotic active against S aureus E coli P aeruginosa and P rettgeri(MICs 0 78-25 Ug/ml) binds to the ribosomal decoding A site to interfere with bacterial protein synthesis
Cayman Chemical 5methoxy TryptamInhydroch 10mg
A peptide FPR2 antagonist (IC50 60 nM) active against E coli P aeruginosa and S pneumoniae from 0 1-100 UM
Cayman Chemical Dexamethason PalmItate 10mg
Reporter Cells are transiently transfected and prepared as frozen stocks using INDIGOs proprietary CryoMite process This cryo-preservation method allows for the immediate dispensing of healthy division-competent reporter cells into assay plates There is no need for cumbersome intermediate treatment steps such as spin-and-rinse of cells viability determinations or cell titer adjustments prior to assay setup
Cayman Chemical Lnsoprazole sulfon NoxIde 10mg
A Met kinase inhibitor (IC50 14 nM) selective for Met over a panel of 62 additional kinases (IC50s 1 UM for all) inhibits proliferation of Met-amplified GTL-16 gastric MKN45 gastric and EBC-1 lung cancer cells (IC50s 66 32 and 82 nM respectively) inhibits Met autophosphorylation in GTL-16 cells and HGF-induced Met phosphorylation in A549 cells (IC50s 7 3 and 22 nM respectively)
Cayman Chemical 3 6-DIsInapoylsucrose 10mg
A disaccharide a degradation product of hemicellulose has been found in T reesei endoxylanase-treated birch kraft pulp
Cayman Chemical GlucosdePNdent Insulnotro 10mg
A bacterial secondary metabolite with antioxidant activity scavenges DPPH radicals in a cell-free assay (IC50 3.23 Ug/ml) has been used in the synthesis of compounds with antibacterial and antifungal activities
Cayman Chemical HIstatIn 8trIfluoroacetAT 10mg
A potential impurity in commercial preparations of (S)-( )-clopidogrel
Cayman Chemical nlumbo nucIfera Lotusn 10mg
A CK2a inhibitor (IC50s 4 2 and 2 3 for the catalytic subunits CK2a and CK2a respectively) selective for CK2a over DYRK2 Plk4 MEK5 and HIPK1 -2 and -3 (IC50s 440 10000 1000 3700 3400 and 8100 nM respectively) decreases phosphorylation of Akt in HCT116 cells from 0 1-10 UM
Cayman Chemical t232trIfluoroacetAT salt 10mg
A TLR7 agonist induces reporter gene activity in HEK293 cells expressing human TLR7 (EC50 7 9 nM) induces production of CXCL10 IL-12p70 IFN-Y and TNF-a in splenocytes isolated from Tlr7 wild-type mice reduces tumor volume and increases survival as well as potentiates the antitumor effects of ionizing radiation in a CT26 murine colon cancer model potentiates the antitumor effects of ionizing radiation and decreases the number of metastases in a KHT murine fibrosarcoma model
Cayman Chemical -Glu-PhetrIfluoroACTAte100mg
A product of 5-LO catalyzed oxidation of arachidonic acid