Custom Peptides
Cayman Chemical 7keto DehydroepIndrosTRon 10mg
An analytical reference standard categorized as a steroid metabolite of dehydroepiandrosterone; reduces ethanol consumption without the hormone-generating effects of dehydroepiandrosterone in rats; intended for research and forensic applications
ABclonal Technology Phospho-IRAK4-Thr345/Ser346 Rabbit pAb
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Cayman Chemical SynthetIc Curzeren 10mg
A sesquiterpene with diverse biological activities; scavenges DPPH radicals in a cell-free assay at 3.36 UG/L with a synergistic effect when used in combination with eucalyptol; active against F. graminearum at 0.5 mg/ml; inhibits the proliferation of SK-MEL-19 melanoma cells (IC50 = 5.17 UG/ml), as well as AGP-01 gastric and HCT116 colon cancer cells (IC50s = 8.04 and 9.18 UG/ml, respectively) and MRC-5 non-cancerous human fibroblasts (IC50 = 11.45 UG/ml); induces apoptosis in, and decreases migration of, SK-MEL-19 cells at 5 and 10 µM; reduces tumor weight in an SPC-A1 mouse xenograft model at 135 mg/kg
Cayman Chemical 1 2DIlInoleoylsnglycero3 10mg
A phospholipid containing the polyunsaturated long-chain (18:2) linoleic acid inserted at the sn-1 and sn-2 positions
Cayman Chemical SynthetIc CarubIcIn 10mg
An anthracycline with anticancer activity; cytotoxic to MCF-7 and K562 cells (IC50s = 90 and 60 nM, respectively), as well as P-glycoprotein-expressing MCF-7/DOX and K562i/S9 cells (IC50s = 90 and 60 nM, respectively)
Cayman Chemical GemIfloxacInmesylate 10mg
A fluoroquinolone antibiotic that is effective against C. pneumoniae and M. tuberculosis (MIC50s = 0.25 and 8 UG/ml, respectively); useful against respiratory tract infections
Cayman Chemical JWH 018 7hydroxyIndl meta 10mg
A minor urinary metabolite of JWH 018; intended for research and forensic applications
Cayman Chemical 2 4DImethylethcathInonhyd 10mg
A disubstituted analog of ethcathinone; intended for forensic and research purposes
Cayman Chemical CID-5951923 10mg
A KLF5 inhibitor (IC50 = 2.3 μM); decreases KLF5 expression in and reduces growth of DLD-1 colorectal adenocarcinoma cells in a concentration-dependent manner; selectively inhibits proliferation of cancer cell lines that highly express KLF5 in the NCI-60 panel of cancer cell lines
Cayman Chemical LIfItegrast 10mg
An inhibitor of the LFA-1/ICAM-1 interaction; binds to LFA-1 and blocks the adhesion of Jurkat T cells or HuT 78 cells to ICAM-1 (IC50s = 2.98 and 9 nM, respectively) and inhibits secretion of various cytokines from these cells; increases tear production in dogs with idiopathic keratoconjunctivitis sicca; topical application inhibits LFA-1-dependent neutrophil recruitment to the eye in mouse models of contact lens-associated corneal inflammation induced by corneal abrasion and tobramycin-killed bacteria
Cayman Chemical RBI 257maleate 10mg
A potent dopamine D4 receptor antagonist (Ki = 0.3 nM) that is selective over D2L, D3, D2-like, and D1 receptors by 1,721-, 439-, 1,336-, and 8,576-fold, respectively.{28464}
Cayman Chemical VulpInIc AcId 10mg
A lichen metabolite with diverse biological activities; active against various bacteria (MICs = 4-16 μg/ml); prevents UVB-induced apoptosis, cytotoxicity, and cytoskeletal modifications in HaCaT human keratinocytes from 25-800 μM; increases scratch wound healing of HaCaT cells; reduces hydrogen peroxide-induced production of ROS and cytotoxicity in HUVECs at 15 μM
Cayman Chemical SyrosngopIn 10mg
An inhibitor of MCT1 and MCT4 (IC50s = 2,500 and 40 nM, respectively); inhibits MCT-facilitated lactate export and decreases intracellular pH in HL-60 promyeloblast cells at 10 µM; decreases cell growth in HL-60 cells at 5 µM in combination with metformin; reduces heart norepinephrine levels, MAP, and pulse rate in normotensive dogs at 0.5 mg/kg, i.v.
Cayman Chemical UR-144 Degradnt 10mg
A common impurity observed during GC-MS analysis of samples containing UR-144, featuring an opened ring presumed to be produced during heating; gives rise to a prominent fragment ion that is 15 amu greater than the base peak of UR-144
Cayman Chemical PhenylpIperazInhydrochLRI 10mg
The base compound from which bioactive drugs, such as the entactogen mCPP, are derived; intended for forensic applications