Custom Peptides
Cayman Chemical MagaInIn 1trIfluoroacetAT 10mg
An antimicrobial cationic peptide; reduces germination percentage and mean tube elongation in kiwi fruit pollen (EC50s = 14 and 15.8 µM, respectively); decreases viral replication in Vero cells infected with HSV-1 or HSV-2 (EC50s = 36.59 and 33.2 µM, respectively) without affecting cell viability (CC50 = >100 µM); induces apoptosis in HL-60 cells at 10 and 50 µM and hemolysis in isolated human erythrocytes at 50 µM; induces DNA fragmentation in HL-60 cells in a reporter assay at 10 and 50 µM
Cayman Chemical TCMCB07trIfluoROCTAte sal 10mg
A peptide antagonist of MC1R, MC3R, MC4R, and MC5R (IC50s = 19.5, 0.59, 13.58, and 8.07 nM, respectively, for the human receptors); an antagonist of dog MC1R, MC3R, MC4R, and MC5R receptors (IC50s = 53.64, 1.46, 7.14, and 11.22 nM, respectively); increases food intake and body weight in a rat model of LPS-induced cachexia at 10 mg/kg; increases body weight, muscle mass, blood urea nitrogen levels, and the mean heart rate in dogs with cachexia at 0.75 mg/kg per day
Cayman Chemical Palovaroten 10mg
An orally bioavailable RARγ agonist; increases RARE activity and decreases IL-1β-induced NF-κB activity in primary mouse stromal cells at 60 nM; inhibits activin A-induced chondrogenic and osteogenic differentiation of mouse FAPs expressing ACVR1R206H at 10 nM; inhibits heterotopic ossification and preserves limb movement and growth in a ACVR1R206H FOP mouse model; decreases heterotopic ossification by 50 to 60% in a rat model of traumatic blast injury at 1 mg/kg per day for 14 days
Cayman Chemical Methylcarbamyl PAF C-16 10mg
Methylcarbamoyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH.{613,4944} It is nearly equipotent with PAF C-16 in its ability to induce platelet aggregation both in isolated platelets and in PRP.{613} In NRK-49 cells overexpressing the PAF receptor, both PAF C-16 and methylcarbamoyl PAF C-16 cause the induction of c-myc and c-fos and the activation of MAPK.{4944} Methylcarbamoyl PAF C-16 induces G1 phase cell cycle arrest, suggesting a potential role for PAF in the inhibition of oncogenic transformation.{4944}
Cayman Chemical PIperoxnhydrochlorIde 10mg
An α2-AR antagonist (Kis = 5.4, 2, and 1.3 nM for α2A-, α2B-, and α2C-ARs, respectively); reverses decreases in systolic blood pressure induced by clonidine in spontaneously hypertensive rats at 10 mg/kg
Cayman Chemical 17phenl trInor ProstglndI 10mg
An F-series PG analog in which the C-1 carboxyl group has been modified to an N-diethyl amide; dialkyl amides such as a 17-p-PGF2α-NEt2 are inert to corneal amidase activity, and are not converted in any detectable amount to the corresponding free acids
Cayman Chemical GSK369796hydrochlorIde 10mg
An antimalarial agent; active against the chloroquine-sensitive P. falciparum strains 3D7 and HB3 (IC50s = 11.2 and 12.6 nM, respectively) and the chloroquine-resistant strain K1 (IC50 = 13.2 nM); reduces parasitemia in mice infected with P. berghei (ED50 = 2.8 mg/kg)
Carbosynth LLC. Poly-L-Lysine Hydrobromide, 0.1g, CAS# 25988-63-0
This item has a minimum order quantity of 3 per supplier requirements
Purity: , M.W. > 12,000 cut off by dialysis, NCA polymerized product, Storage Temperature: -20C
Cayman Chemical RalmItaront 10mg
A TAAR1 agonist; induces cAMP accumulation in HEK293T cells expressing human TAAR1 (EC50 = 17.78 nM)
Cayman Chemical SynthetIc DIctamnIn 10mg
An alkaloid with diverse biological activities; inhibits arachidonic acid-, collagen-, thrombin-, or PAF-induced platelet aggregation in washed isolated rabbit platelets at 100 UG/ml; cytotoxic to human KB oral, HeLa cervical, and DLD-1 colon cancer cells (EC50s = 20.55, 2.5, and 6.4 UG/ml, respectively) and induces apoptosis in A549, PC-9, and EBC-1 human lung cancer cells from 50-200 µM; increases serum ALT and ALP activities and induces hepatocyte necrosis in mice at 150 or 200 mg/kg
Cayman Chemical 5bromo4chLRo3Indolyl 10mg
A chromogenic substrate for β-glucuronidase; upon cleavage by β-glucuronidase, an indigo pigment is released that can be used as a marker of β-glucuronidase activity
Cayman Chemical Cheldonn 10mg
A benzophenanthridine alkaloid; induces Bcl-2- and caspase-dependent apoptosis in HepG2 human liver carcinoma cells (LD50 = 12 µM) and in Jurkat human T cells at 1 µM; downregulates hTERT expression, reduces telomerase activity, and induces cell senescence in HepG2 cells