Custom Peptides
Cayman Chemical 6-bromo-MDMAhydrochlorIde 10mg
Differs structurally from 3,4-MDMA in that it has a bromine group added at the two position of the phenyl ring
Cayman Chemical BusRelInNHNH2trIfluoROC 10mg
A synthetic GnRH agonist; at least 20 times more potent than GNRH; decreases the level of circulating gonadotropins and sex hormones after an initial increase; reduces tumor growth in a DMBA-induced rat model of mammary cancer when used at a dose of 20 UG/kg; induces enteric neurodegeneration, decreasing the number of luteinizing hormone receptor-positive neurons in the rat gastrointestinal tract when administered at a dose of 1 mg/kg for 5 days
Cayman Chemical SureLIghtPE-695 10mg
An atypical antipsychotic an agonist of 5-HT1A receptors (EC50 36.31 nM for inhibition of forskolin-induced adenylate cyclase activity in HeLa cells expressing human receptors) as well as an inverse agonist of 5-HT1D receptors (IC50 2.69 nM) and a partial agonist of 5-HT1B receptors (EC50 6.17 nM) in [35S]GTPYS binding assays an antagonist at 5-HT2A and dopamine D2 receptors (Kis 1.15 and 1.29 nM respectively) in cell-based assays inhibits d-amphetamine-induced hyperactivity and apomorphine-induced stereotypy in rats (ID50s 1.53 and 2.43 mg/kg respectively)
Cayman Chemical A20FMDV2trIfluoROCTAte sa 10mg
A peptide; inhibits αVβ6 integrin-dependent cell adhesion in H357 cells expressing human αVβ6 (IC50 = 1.2 µM); When coupled with 111indium-DTPA, A20FMDV2 binds to αVβ6 integrin endogenously expressed for radiation imaging analysis in a MCF10CA1a breast cancer mouse xenograft model at 20 MBq
Cayman Chemical GlucosdePNdent Insulnotro 10mg
An inducer of insulin secretion; enhances glucose-induced insulin release in primary rat pancreatic β-cells at 100 nM to a greater extent than glucose and GIP (1-42)
Cc1ccc(O)cc1 | 100g | 205389994](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3863424.jpg-250.jpg)
eMolecules 16874-12-7 | H-Tyr-OtBu | Combi-Blocks | MFCD00042644 | 237.299 | C13H19NO3 | 97.000 | CC(C)(C)OC(=O)[C@@H](N)Cc1ccc(O)cc1 | 100g | 205389994
H-Tyr-OtBu | Combi-Blocks | 16874-12-7 | MFCD00042644 | 237.299 | C13H19NO3 | 97.000 | CC(C)(C)OC(=O)[C@@H](N)Cc1ccc(O)cc1 | 100g | 205389994
Cayman Chemical TatCBD3A6KtrIfluoroACTAte 10mg
A peptide; prevents decreases in the paw withdrawal threshold in a rat model of stavudine-induced antiretroviral neuropathic pain at 10 mg/kg and decreases the number of action potentials from DRG neurons isolated from the same rats; dural administration decreases capsaicin-induced meningeal blood flow in rats
Cayman Chemical CarboxyamIdotrIazole 10mg
An orally bioavailable, non-selective calcium channel blocker; blocks L- and T-type calcium channels in GH3 rat pituitary cancer cells (IC50s = 0.5 and 1.5 μg/ml, respectively); blocks carbachol- and A23187-stimulated calcium influx in CHO cells expressing human recombinant M5 receptors (IC50s = 935 and 359 nM, respectively); inhibits the growth of T. gondii in non-cancerous human fibroblasts and HeLa human cervical cancer cells (IC50 = 0.06 μg/ml for both); inhibits the growth of human FaDu and EVSCC17M squamous cell carcinoma cells (IC50s = 13 and 15 μM, respectively) and of HUVECs (IC50 = 1 μM); inhibits angiogenesis in a chicken chorioallantoic membrane assay in vivo at 20 μM
Cayman Chemical nuropeptIde EIratrIflu 10mg
An endogenous peptide fragment of rat prepro-MCH; expressed in both the central and peripheral nervous systems, localizes to the cytoplasm, and colocalizes with MCH in the CNS; reduces TRH release in mediobasal hypothalamus explants at 1 µM; increases serum levels of LH in male rats and in chronically ovariectomized female rats that received estradiol benzoate and progesterone in addition to NEI; induces excessive grooming behavior and increases locomotor activity in rats at 1 UG/animal; increases the amount of time spent in REM sleep in rats when injected intracerebroventricularly or into the vlPAG
Cayman Chemical BrequInarsodIum salt 10mg
A DHODH inhibitor (IC50 = ~20 nM); selective for DHODH over a panel of greater than 400 kinases at 100 nM; induces differentiation of ER-HoxA9, U937, and THP-1 cells in vitro (EC50s = ~1 µM); induces differentiation of tumor cells and reduces tumor growth in a THP-1 mouse xenograft model at 15 mg/kg three times daily or 5 mg/kg per day; induces differentiation of bone marrow leukemic cells and increases survival In a retroviral transduction mouse model of HoxA9 + Meis1 AML
Cayman Chemical 5bromo4chLRo3Indolyl 10mg
A chromogenic substrate for β-glucuronidase; upon cleavage by β-glucuronidase, an indigo pigment is released that can be used as a marker of β-glucuronidase activity
Cayman Chemical IsobutyrylCoenzyme AsodIM 10mg
A short-chain branched acyl CoA; a substrate for IBDH
Cayman Chemical 10Chloroestra1 4dIen3 17 10mg
A sterone ERα agonist; increases reporter gene expression in S. cerevisiae (EC50 = 0.36 nM for the human receptor); an aromatase inhibitor (IC50 = 2.4 µM)
Cayman Chemical 1Naphthyl 3 5DNItrobenzAT 10mg
A dual 5-LO and mPGES-1 inhibitor (IC50s = 1 and 3.6 µM, respectively)