Custom Peptides
Cayman Chemical 4AmInomethyl4 5 8trImeth 10mg
A bifunctional photoreactive agent for crosslinking nucleic acids; intercalates into double-stranded regions in DNA or RNA and, upon UV irradiation, forms covalent adducts with pyrimidine bases; used to study different types of RNA from diverse organisms, including viruses
Cayman Chemical 1 3DIpalmItoyl2lnoloyl G 10mg
A triacylglycerol; has been found in the palm stearin fraction of palm oil and as a minor component of soybean germ oil
Cayman Chemical GInkgolIde J 10mg
A terpene trilactone with diverse biological activities; inhibits PAF-induced platelet in rabbit and human platelet-rich plasma (IC50s = 27 and 43.5 μg/ml, respectively); inhibits Aβ42-induced cell death in primary rat hippocampal neurons and Aβ42-induced impairment of LTP in the mouse CA1 region at 1 μM
Cayman Chemical LM11A-31hydrochlorIde 10mg
A p75NTR ligand; inhibits NGF binding to p75NTR-Fc (A2 = 1,192 nM); inhibits DNA damage in and promotes survival of hippocampal neuronal cultures in a p75NTR- and concentration-dependent manner; prevents neurodegeneration in various mouse models of injury and neurodegenerative disease
Cayman Chemical SucIleGlu pIpGlyArgpN 10mg
A colorimetric Factor Xa substrate; cleavage of the IE(γ-pip)GR peptide sequence releases pNA, which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity
Cayman Chemical Boldenon CypIonate 10mg
An ester of boldenone, an anabolic androgenic steroid; intended for forensic and research purposes only
Cayman Chemical Seco RapamycInsodIum salt 10mg
A nonenzyme-dependent degradation product of rapamycin resulting from ester hydration followed by dehydration; secreted from cells by P-glycoprotein; poorly activates mTOR but, like rapamycin, inhibits the proteasome
Cayman Chemical Phellandrene 10mg
A cyclic monoterpene with apoptotic activity; cytotoxic to RAW 264.7 cells at 50-200 UG/ml; induces apoptosis in RAW 264.7 cells
Cayman Chemical SynthetIc AvIcularIn 10mg
A flavonoid glycoside with diverse biological activities; inhibits FASN and aldose reductase (IC50s = 6.15 and 19.05 µM for the chicken liver and human enzymes, respectively); scavenges DPPH and superoxide radicals, as well as inhibits copper-induced oxidation of LDL in cell-free assays (IC50s = 64.3, 6, and 3.8 µM, respectively); inhibits LPS-induced increases in NO and PGE2 production in RAW 264.7 macrophages at 30-300 µM; inhibits the proliferation, migration, and invasion of, as well as induces apoptosis and cell cycle arrest at the G0/G1 phase in, Huh7 cells at 100 UG/ml
Cayman Chemical 7-APBhydrochlorIde 10mg
An analytical reference standard categorized as a benzofuran; a potential metabolite of 7-MAPB based on the published metabolism of 5-MAPB; intended for research and forensic applications
Cayman Chemical LoureIrIn B 10mg
A flavonoid with diverse biological activities; inhibits Kv1.3-mediated currents, induces membrane depolarization, and reduces calcium influx in Jurkat T cells; inhibits phytohemagglutinin-induced IL-2 release in Jurkat T cells; reduces type I collagen and fibronectin protein levels in TGF-β1-stimulated fibroblasts as well as contraction of TGF-β1-stimulated fibroblasts in a gel contraction assay at 25 μg/ml; reduces type I collagen and fibronectin protein levels and inhibits phosphorylation of ERK and JNK in isolated human hypertrophic scar tissue; increases glucose absorption and intracellular ATP levels in Ins-1 cells
Cayman Chemical RCS4 N 5carboxypentyl met 10mg
An expected metabolite of RCS-4, which should be detectable in the urine
Cayman Chemical EpothIlon B 10mg
A macrolide that causes the formation of bundles of intracellular microtubules in non-mitotic cells, induces the formation of hyperstable tubulin polymers, and arrests cell cycling in mitosis; induces mitotic arrest at nanomolar IC50 values in cell lines from ovarian, breast, lung, colon, prostate, and squamous cancer
Cayman Chemical AcebIlustat 10mg
An inhibitor of LTA4 hydrolase; reduces the transmigration of PMNs from an epithelial monolayer to airway supernatant isolated from patients with cystic fibrosis at 1 µM