Custom Peptides
Cayman Chemical Atenolol 10mg
An enantiomer of (±)-atenolol; inhibits radioligand binding to β-ARs on sarcolemma-enriched membranes (Ki = 8.61 µM); has no effect on blood pressure in spontaneously hypertensive rats
Cayman Chemical BazedoxIfenacetate 10mg
An indole-based SERM that binds to both ERα (IC50 = 26 nM) and ERβ (IC50 = 99 nM); antagonizes 17β-estradiol-dependent and hormone-independent growth of breast cancer cell proliferation (80% reduction with 10 nM) in a manner related to cell cycle arrest and downregulation of cyclin D1 and ERα
Cayman Chemical Amodaqun 10mg
A prodrug form of N-desethyl amodiaquine; active against several strains of P. falciparum in vitro (EC50s = 0.23-0.52 nM) and exhibits a synergistic effect when used in combination with N-desethyl amodiaquine; dose-dependently inhibits development of parasitemia in a mouse model of P. berghei infection
Cayman Chemical 3BromotyrosIntrIfluoroace 10mg
A product of protein oxidation; a marker of eosinophil peroxidase-induced protein oxidation in vitro and in vivo
Cayman Chemical 10 E-PentadecenoIc AcId 10mg
A 15-carbon monounsaturated fatty acid; inhibits IFN-γ-induced production of kynurenine in THP-1 cells by 14%; has been used in studies of alternative β-oxidation pathways
Cayman Chemical LeukadherIn 1 10mg
An allosteric activator of CD11b/CD18; increases K562 cell adhesion to fibrinogen (EC50 = 4 µM); reduces rolling velocity of leukocytes, decreasing the number of leukocytes recruited to injured tissue; anti-inflammatory in a zebrafish tailfin injury model and a mouse model of nephritis; competitively inhibits YopH (Ki = 1.94 µM) and anthrax lethal factor metalloproteinase (IC50 = 6 µM)
Cayman Chemical 5 NethylNIsopropylAmIlo 10mg
A potent inhibitor of several NHE isoforms, inhibiting NHE1, NHE2, NHE3, and NHE5 with Ki values of 0.02, 0.5, 2.4, and 0.42 μM, respectively; less effectively inhibits NHE4 (IC50 ≥10 μM)
Cayman Chemical BEChydrochlorIde 10mg
An inhibitor of arginase types I and II; inhibits rat liver arginase I (Kis = 0.4 and 0.6 µM from kinetic analyses); inhibits human arginase II (Kis = 310 and 30 nM at pH 7.5 and 9.5, respectively); enhances nitric oxide-dependent relaxation of human penile corpus cavernosum smooth muscle in vitro at 0.1-1 mM
Cayman Chemical 3-deoxy Glucoson 10mg
A highly reactive 2-oxoaldehyde intermediate of the Maillard reaction produced during oxidative stress in response to excess sugar consumption and in association with diabetes; glycates and crosslinks proteins leading to the formation of advanced glycation endproducts
Cayman Chemical 3 4MethylendIoxy PV9hydro 10mg
A cathinone whose physiological and toxicological properties are not known
Cayman Chemical 4methoxy PV9hydrochLRIde 10mg
Differs from PV9 by having a methoxy group at the four, or para, position of the phenyl group
Cayman Chemical Fmoc-Glu OtBu-OSu 500mg
An amino acid-containing building block; used in the synthesis of bis- and tris-branched carboxyl group-terminal PEGylating reagents; has been used in the synthesis of N3S chelators
Cayman Chemical TFB-TBOAhydrate 10mg
An inhibitor of EAAT1 and EAAT2 (IC50s = 22 and 17 nM for EAAT1 and EAAT2, respectively); selective for EAAT1 and EAAT2 over EAAT3 (IC50 = 300 nM), as well as a variety of neurotransmitter transporters and receptors at 10 µM; inhibits L-glutamate- and L-aspartate-induced currents in X. laevis oocytes at 10 µM; induces convulsions in mice at 0.2 UG/animal
Cayman Chemical 5-trns Fluprostenol 10mg
A potential impurity in commercial preparations of fluprostenol
Cayman Chemical AcIETDAFCtrIfluoroACTAte 10mg
A fluorogenic substrate that can be cleaved specifically by caspase-8, caspase-3 processing enzyme, caspase-10, and granzyme B