Protein Analysis Reagents
Protein Analysis Reagents
Tocris Bioscience™ A23187, free acid
CAS: 52665-69-7 Molecular Formula: C29H37N3O6
Cayman Chemical chartreusIs A23187 5mg
Antigen phosphopeptide corresponding to amino acid residues surrounding phospho-Ser31 of rat TH Host rabbit Cross Reactivity ( ) mouse and rat TH Applications WB IF (frozen sections) and IHC (frozen sections)
Cayman Chemical 4-bromo A23187 5mg
The first described limonoid a group of compounds known to impart bitter flavor in citrus fruits reported to demonstrate anti-proliferative and proapoptotic activity on several cancer cell lines as well as pesticidal anti-malarial anti-microbial and anti-HIV activity
Lkt Laboratories 4-bromo-A23187, ≥98%, 1MG
Non-fluorescent halogenated A23187 analog, Ca2+ ionophore. CAS: 76455-48-6. Additional sizes available upon request. Ships from Saint Paul, MN.
Cayman Chemical alcIs4 7 10 13 16Docosape 5mg
An oxidized phospholipid formed in A23187-activated monocytes by direct oxidation of endogenous PE
Cayman Chemical Gap 26trIfluoroacetAT salt 5mg
A natriuretic peptide increases ex vivo A23187-induced vasorelaxation in porcine hearts isolated from a model of acute coronary occlusion at 2 Ug/kg bolus dose followed by 0 01 Ug/kg per minute infusion
Cayman Chemical STng PROTAC SP23 1mg
A prenylated coumarin with anti-inflammatory and neuroprotective activities inhibits TPA- and A23187-induced histamine release from HMC-1 cells at 10 UM protects against glutamate-induced cytotoxicity in primary rat cortical cells at 0.1-10 UM
Cayman Chemical AlexamorelIntrIfluoroACTAt 5mg
A natriuretic peptide increases ex vivo A23187-induced vasorelaxation in porcine hearts isolated from a model of acute coronary occlusion at 2 Ug/kg bolus dose followed by 0 01 Ug/kg per minute infusion
Cayman Chemical 4-O-MethylhonkIol 5mg
CAY10502 s a potent nhbtor of cPLA2a wth an C50 value of 4 3 nM for the purfed enzyme from human platelets 14126 t nhbts arachdonc acd moblzaton from A23187-stmulated or TPA-stmulated human platelets wth C50 values of 570 and 0 9 nM respectvely 14126
Cayman Chemical TrnsfRrIn RECPTR ProteIn 100uL
A major active metabolite of metamizole inhibits A23187-induced PGE2 production in isolated mouse peritoneal macrophages at 0.1 mM increases the paw withdrawal threshold in a rat model of carrageenan-induced hyperalgesia at 160 Ug/paw reduces LPS-induced pyrexia in rats at 60 90 and 120 mg/kg a potential impurity found in commercial preparations of metamizole
Cayman Chemical 7-epI-10-Deacetyltaxol 5mg
A coumarin with diverse biological activities reduces A23187-induced release of PGE2 and LTC4 in isolated mouse peritoneal macrophages active against S. aureus S. epidermidis B. subtilis S. lutea and V. cholera (MICs 0.5 0.75 0.75 0.75 and 0.5 mg/ml respectively) reduces formalin-induced paw licking and biting responses in mice at 3 and 7.5 mg/kg
CPC Scientific Z-Val-Phe-CHO 1MG
Potent and cell permeable calpain I and II inhibitor that reduces capsaicin-mediated cell death in cultured dorsal root ganglionand. This peptide is additionally a gamma-secretase-inhibitor that reduces occurrence of apoptosis in H2O2 and A23187 treated PC12 cells.ONE-LETTER SEQUENCE: Z-VF-CHOMOLECULAR FORMULA: C22H26N2O4MOLECULAR WEIGHT:382.5STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [88191-84-8], RESEARCH AREA: Apoptosis
CPC Scientific Z-Val-Phe-CHO 0.5MG
Potent and cell permeable calpain I and II inhibitor that reduces capsaicin-mediated cell death in cultured dorsal root ganglionand. This peptide is additionally a gamma-secretase-inhibitor that reduces occurrence of apoptosis in H2O2 and A23187 treated PC12 cells.ONE-LETTER SEQUENCE: Z-VF-CHOMOLECULAR FORMULA: C22H26N2O4MOLECULAR WEIGHT:382.5STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [88191-84-8], RESEARCH AREA: Apoptosis
Cayman Chemical ANTIBODYS-NIFE 5mg
An inhibitor of IKCa1/KCa3.1 channels (IC50 9.4 nM) inhibits A23187-induced hyperpolarization of human mouse and rat erythrocytes (IC50s 14 15 and 9 nM respectively) selective over Nav and most Kv channels as well as 65 receptors and channels in a panel inhibits T-lymphocyte activation and cytokine release in vitro (IC50 ~50 nM) decreases colon inflammation and improves weight gain in a rat model of DNBS-induced IBD
Cayman Chemical -Talnolol 5mg
A 5-LO inhibitor (IC50 15 nM) selective for 5-LO over 12-LO and 15-LO (IC50s 500 and 300 nM respectively) inhibits A23187-induced 5-LO product formation in isolated human PMNs monocytes and whole blood (IC50s 0.5 0.45 and 1.5 UM respectively) increases survival in a mouse model of PAF-induced lethal shock at 3.5 mg/kg reduces pleural levels of LTB4 in a rat model of carrageenan-induced pleurisy
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