Bioactive Small Molecules
Revvity Health Sciences Inc HTRF Human Total CHK-2 Detection Kit, 50,000 Assay Points
HTRF Human Total CHK-2 Detection Kit, 50,000 Assay Points
Medchemexpress LLC HY-13631AS 10mg , Exatecan-d5 (mesylate) CAS: Purity:>98%
HY-13631AS 10mg Exatecan-d5 (mesylate) CAS: Exatecan-d5 mesylate (DX8951f-d5) is deuterium labeled Exatecan mesylate. Exatecan mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 0.975 μg/mL. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-B0069 10mg , Fludarabine CAS:21679-14-1 Purity:>98%
HY-B0069 10mg Fludarabine CAS: 21679-14-1 Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes[4]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-15921 10g , IPTG CAS:367-93-1 Purity:>98%
HY-15921 10g IPTG CAS: 367-93-1 IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Suc-Ala-Glu-Pro-Phe-pNA | 128802-76-6 | 99.5% | 682.68 | 5 MG
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidyl-prolyl isomerase Pin1. It is utilized to assess the inhibitory effect of target compounds on Pin1, the catalytic activity of Pin1, and other related assays.
- Functions as a substrate for recombinant human Pin1 in cell-free protease-coupled PPIase assays.
- Enables measurement of Pin1 isomerase activity via pNA release.
- Specifically elutes phage bound to the Pin1 PPIase domain active site.
- Acts as a substrate for GST-tagged Pin1 PPIase activity.
- Serves as a substrate for recombinant human Pin1's PPIase activity, which is inhibited by PKA phosphorylation.
Medchemexpress LLC HY-128952 1mg , Tesirine CAS:1595275-62-9 Purity:>98%
HY-128952 1mg Tesirine CAS: 1595275-62-9 Tesirine (SG3249) is an antibody-drug conjugate (ADC) pyrrolobenzodiazepine (PBD) dimer payload. Tesirine combines potent antitumor activity with desirable physicochemical properties such as favorable hydrophobicity and improved conjugation characteristics. SG3199 (HY-101161) is the released warhead component of the ADC payload Tesirine. SG3199 retains picomolar activity in a panel of cancer cell lines. PBD dimers are highly efficient DNA minor groove cross-linking agents with potent cytotoxicity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-109566 10mg , AZD1390 CAS:2089288-03-7 Purity:>98%
HY-109566 10mg AZD1390 CAS: 2089288-03-7 AZD1390 is a potent, highly selective, orally bioavailable, brain-penetrant ATM inhibitor with an IC50 of 0.78 nM in cell. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-13912 5mg , IWP-2 CAS:686770-61-6 Purity:>98%
HY-13912 5mg IWP-2 CAS: 686770-61-6 IWP-2 is an inhibitor of Wnt processing and secretion with an IC50 of 27 nM. IWP-2 targets the membrane-bound O-acyltransferase porcupine (Porcn) and thus preventing a crucial Wnt ligand palmitoylation. IWP-2 is also an ATP-competitive CK1δ inhibitor with an IC50 of 40 nM for the gatekeeper mutant M82FCK1δ. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-A0070A 100mg , Liothyronine CAS:6893-02-3 Purity:>98%
HY-A0070A 100mg Liothyronine CAS: 6893-02-3 Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-A0281 500mg , 4-Phenylbutyric acid CAS:1821-12-1 Purity:>98%
HY-A0281 500mg 4-Phenylbutyric acid CAS: 1821-12-1 4-Phenylbutyric acid (4-PBA) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-50879 50mg , Elacridar CAS:143664-11-3 Purity:>98%
HY-50879 50mg Elacridar CAS: 143664-11-3 Elacridar is an orally active P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) inhibitor. Elacridar can be used to examine the influence of efflux transporters on drug distribution to brain and the research of cancer. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-B0256 500mg , Azathioprine CAS:446-86-6 Purity:>98%
HY-B0256 500mg Azathioprine CAS: 446-86-6 Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-13750 100mg , Ebselen CAS:60940-34-3 Purity:>98%
HY-13750 100mg Ebselen CAS: 60940-34-3 Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker. Ebselen potently inhibits Mpro (IC50=0.67 μM) and COVID-19 virus (EC50=4.67 μM).Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity[4][5]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-10569 10mg , Ponesimod CAS:854107-55-4 Purity:>98%
HY-10569 10mg Ponesimod CAS: 854107-55-4 Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-121320 5mg , Raptinal CAS:1176-09-6 Purity:>98%
HY-121320 5mg Raptinal CAS: 1176-09-6 Raptinal, a agent that directly activates caspase-3, initiates intrinsic pathway caspase-dependent apoptosis. Raptinal is able to rapidly induce cancer cell death by directly activating the effector caspase-3, bypassing the activation of initiator caspase-8 and caspase-9. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.