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Filtered Search Results
Cayman Chemical C18 -2-hydroxy dIhydro 5mg
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A 2'-hydroxylated form of C18 dihydro ceramide
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ALADDIN SCIENTIFIC CORPORATION LY593093-5MG
NC3780263 LY593093-5MG
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Atmar Glass Company PTC-500 CELLS
NC3834054 PTC-500 CELLS
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AdipoGen BHHT
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Chemical. CAS 200862-69-7. Formula C30H16F14O4. MW 706.42. Synthetic. Chelating label for europium Eu3. Builds luminescent complexes that can be directly bound to proteins and detected.
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Medchemexpress LLC (R)-(-)-Gossypol acetic acid | 866541-93-7 | C32H34O10 | 5 MG
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(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) is the levorotatory isomer of the natural product Gossypol. It is a research chemical that binds to Bcl-2, Mcl-1, and Bcl-xL proteins, making it suitable for studies in apoptosis and autophagy pathways.
- Purity of 98.93%
- Molecular weight of 578.61
- Chemical formula C32H34O10
- Appears as a solid, light yellow to brown
- Targets Mcl-1 (170 nM Ki), Bcl-2 (260 nM Ki), and Bcl-xL (480 nM Ki)
- More potent than (+)-Gossypol in inhibiting cell growth and inducing apoptosis
- Shows potent activity against head and neck squamous cell carcinomas cell lines in vitro
- Induces apoptosis in HNSCC tumor cells with functional p53 and kills mutant p53 tumor cells by a different mechanism
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Cayman Chemical ANTIBODY PamapImod 5mg
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A potent, selective inhibitor of p38α MAPK (IC50 = 14 nM); blocks inflammatory signaling in cells, whole blood, and synovial explants; orally bioavailable, abrogating inflammation, bone, and pain in animal models
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Selleck Chemical LLC IACS-010759 S8731-1G
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IACS-010759 (IACS-10759) is a potent and selective oxidative phosphorylation inhibitor (IC50 10 nM) that blocks cellular respiration through inhibition of complex I
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Cayman Chemical PlntamajosIde 5mg
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A phenylethanoid with diverse biological activities; scavenges DPPH radicals in a cell-free assay (IC50 = 11.8 µM); inhibits 5- and 15-LO (IC50s = 0.375 and 96 µM, respectively); decreases viability of TE-1 ESCC cells at 20-320 UG/ml, as well as inhibits LPS-induced EMT in Eca-109 and TE-1 cells and decreases phosphorylated NF-κB levels in TE-1 cells; inhibits arachidonic acid-induced mouse EAr edema at 3 mg/ear
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Medchemexpress LLC (Rac)-Acolbifene | 151533-34-5 | 98.2% | 457.56 | 100 MG
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(Rac)-Acolbifene is the racemic form of EM652, an estrogen receptor antagonist. It exhibits both anti-estrogenic and estrogenic activities. This compound features a piperidine ring and has a good pharmacological profile, with a relative binding affinity (RBA) of 380.
- It is an estrogen receptor antagonist.
- It demonstrates anti-estrogenic and estrogenic activities.
- It contains a piperidine ring.
- It shows a good pharmacological profile.
- It has a relative binding affinity (RBA) of 380.
- It shows an inhibitory effect in T-47D cells with an IC50 value of 0.110 nM.
- In vivo administration shows significant antiuterotrophic inhibitions in ovariectomized mice.
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AdipoGen Sipholenol A (100 µg)
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Chemical. CAS: 78518-73-7. Formula: C30H52O4. MW: 476.7. Isolated from marine sponge Siphonochalina siphonella. Efficient inhibitor of P-glycoprotein (Pgp, MDR-1) function through direct interactions. By inhibiting MDR-1, active compounds remain in the cytoplasm longer and allowing them to be more effective within the cell. Reversing agent for the treatment of multidrug resistance (MDR) in Pgp-overexpressing tumors. Potentiates the cytotoxicity of established P-gp substrates such as colchicine, vinblastine and paclitaxel. Antiproliferative and cytotoxic compound. Potent antifouling compound.
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Fluidigm Corp STANDARD BIOTOOLS INC
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NC3986621 CONTROL LINE FLUID 150UL X4
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Perkin Elmer US LLC PERKIN ELMER US LLC
NC3988802 POLYETHYLENE TUBING
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![Medchemexpress LLC 2-[(2E)-2-(1-azabicyclo[2.2.2]oct-3-ylidene)-2-fluoroethoxy]-9H-carbazole HCl | 182959-33-7 | 99.4% | 372.86 g/mol | C21H22ClFN2O | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000214202.png-250.jpg)
Medchemexpress LLC 2-[(2E)-2-(1-azabicyclo[2.2.2]oct-3-ylidene)-2-fluoroethoxy]-9H-carbazole HCl | 182959-33-7 | 99.4% | 372.86 g/mol | C21H22ClFN2O | 1 ML
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YM-53601 is a squalene synthase inhibitor used in biochemical and cellular research to probe cholesterol biosynthesis and lipid metabolism. It is provided as a dry solid or as a ready-to-use 10 mM solution in DMSO (1 mL), and is characterized by molecular formula C21H22ClFN2O, molecular weight 372.86 g/mol, and CAS 182959-33-7.
- Squalene synthase inhibitor useful for cholesterol pathway studies.
- Available as solid or 10 mM solution in DMSO for immediate use.
- High purity suitable for biochemical and cell-based assays.
- Includes structural identifiers for compound confirmation.
- Storage recommendations provided to preserve stability.
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Medchemexpress LLC VAV1 degrader-2 | 3050683-29-6 | 98.2% | 393.87 | 5 MG
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VAV1 degrader-2 (Example 176) is a molecular glue degrader that targets VAV 1 with a DC50 of 4.41 nM. It can be used in the study of inflammatory and autoimmune diseases.
- Molecular glue degrader
- Targets VAV 1
- For research use only
- Appearance: Solid
- Color: White to off-white
- Useful in the study of inflammatory and autoimmune diseases
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AdipoGen DAR-4MT
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Chemical. CAS 339527-82-1. Formula C25H23N5O3. MW 441.49. Synthetic Reference compound for the fluorescent nitric oxide NO probe DAR-4M.
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