Bioactive Small Molecules
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Filtered Search Results
Medchemexpress LLC SMI-16a | 587852-28-6 | MFCD31382191 | 98.0% | 263.31 g·mol⁻¹ | C13H13NO3S | 1 ML
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SMI-16a is a small-molecule research reagent that selectively inhibits Pim family kinases and is used to probe Pim-mediated signaling and cellular responses in vitro and in vivo. It shows potent biochemical activity against Pim1 and Pim2 and demonstrable cellular activity in prostate cancer cells.
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Medchemexpress LLC β-nicotyrine | 487-19-4 | MFCD00468104 | 158.20 | C10H10N2 | 10 MG
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β-Nicotyrine is a minor tobacco alkaloid and a metabolite of nicotine supplied as an analytical standard for research and analytical applications. The compound is suitable for metabolic and analytical studies and is provided in small vial quantities for laboratory use.
- Used as an analytical standard and research reference material.
- CAS number 487-19-4.
- Molecular formula C10H10N2; molecular weight 158.20.
- Available in small vial pack sizes, for example 10 MG.
- Recommended storage: solid -20°C (stable for 3 years); in solvent -80°C (6 months) or -20°C (1 month).
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Apexbio Technology LLC Rizatriptan Benzoate 145202-66-0 50mg
Rizatriptan Benzoate (CAS 145202-66-0) is a synthetic small molecule structurally related to tryptamine that acts as a selective agonist at serotonin 5-HT1D receptors By targeting these G protein-coupled receptors Rizatriptan Benzoate modulates the release of vasoactive neuropeptides and inhibits neurogenic inflammation and vasodilation associated with cranial blood vessels This pharmacological profile has made it a valuable tool for investigating serotonergic signaling pathways receptor pharmacodynamics and migraine pathophysiology in preclinical research settings
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Cayman Chemical Verdiperstat, Purity: ≥98%, CAS: 890655-80-8, 5 mg
An irreversible inhibitor of MPO (IC50 = 630 nM); selective for MPO over a panel of 130 enzymes, transporters, and ion channels (IC50s = >50 µM for all); reduces MPO expression, prevents an increase in neuronal loss, and prevents decreases in motor score and stride length in a PLP-αSYN transgenic mouse model of multiple system atrophy at 180 µmol/kg, p.o.
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Selleck Chemical LLC BAR502 S0033-25MG
BAR502 (Compound 30) is a dual FXR and GPBAR1 agonist with IC50 values of 2 M and 0 4 M respectively
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Selleck Chemical LLC MOMIPP E2933-25MG
MOMIPP a macropinocytosis inducer is a PIKfyve inhibitor MOMIPP readily penetrates the blood-brain barrier and is moderately effective in suppressing progression of intracerebral glioblastoma xenografts
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Selleck Chemical LLC P7C3-A20 | 1235481-90-9 | 506.2 g/mol | 5MG
P7C3-A20 | 1235481-90-9 | 506.2 g/mol | 5MG
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Medchemexpress LLC SHP394 | 100MG
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SHP394 is an orally active selective and allosteric inhibitor of SHP2 with an IC50 of 23 nM[1]
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Medchemexpress LLC Trimetazidine dihydrochloride | 13171-25-0 | MFCD00243086 | 99.9% | 339.26 | C14H24Cl2N2O3 | 10 MG
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Trimetazidine dihydrochloride is the dihydrochloride salt of trimetazidine, used as an antianginal agent and as a reference standard in analytical and pharmacological research. Supplied in precisely weighed small pack sizes for assay and QC applications.
- Reference standard for analytical and pharmacological assays.
- Cas number 13171-25-0.
- Chemical formula C14H24Cl2N2O3.
- Molecular weight 339.26.
- Purity 99.94% (as listed).
- Available in small pack sizes such as 10 mg.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Cayman Chemical GRL-0496, Purity: ≥98%, CAS: 1087243-14-8, 1 mg
An inhibitor of SARS-CoV and SARS-CoV-2 Mpro (IC50s = 0.03 and 0.038 µM, respectively); reduces viral infectivity in SARS-CoV-infected Vero cells (EC50 = 6.9 µM)
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QA Bio Inc Ludger Glucose Ladder - Procainamide
The procainamide glucose homopolymer (GHP) ladder derived from digested wheat starch used as a standard for sizing of glycans. Amount supplied sufficient for 30 HPLC runs. • The GHP ladder is also available labeled with 2-AB (CAB-GHP-30), 2-AA(CAA-GHP-30) and procainamide(PROC-GHP-30 . • Sources: Derived from wheat starch • Form: Dry. Dried by centrifugal evaporation from an aqueous solution. • Amount: 100 picomoles • Purity: > 90% pure as assessed by a combination of HPLC
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Cayman Chemical Macitentan, Purity: ≥98%, CAS: 441798-33-0, 100 mg
A dual ETA/ETB receptor antagonist (IC50s = 0.5 and 391 nM in a radioligand binding assay using recombinant ETA and ETB, respectively); inhibits ET-1-induced intracellular Ca2+ increase in HPASMCs (IC50 = 0.9 nM) and contractions of isolated rat aortic rings (pA2 = 7.6 for ETA) and sarafotoxin S6c-induced contractions of isolated rat tracheal rings (pA2 = 5.9 for ETB); decreases mean arterial blood pressure in DOCA-salt hypertensive rats (ED50 = 1 mg/kg); prevents development of pulmonary hypertension and right ventricle hypertrophy in a rat model of hypertension; decreases the number of vascular and tubule-interstitial lesions and amount of glomerular damage in a rat model of diabetes
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Medchemexpress LLC ROSIPTOR 10 MM 1 ML IN DMSO
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Rosiptor (Synonyms: AQX-1125)Size: 10 mM * 1 mL in DMSO
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Cayman Chemical BEC (hydrochloride), Purity: ≥95%, CAS: 222638-67-7, 5 mg
An inhibitor of arginase types I and II; inhibits rat liver arginase I (Kis = 0.4 and 0.6 µM from kinetic analyses); inhibits human arginase II (Kis = 310 and 30 nM at pH 7.5 and 9.5, respectively); enhances nitric oxide-dependent relaxation of human penile corpus cavernosum smooth muscle in vitro at 0.1-1 mM
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Beckman Coulter LUCID DURACartridge 11A
LUCID DURACartridge 11A
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