Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

Search Within Results

6,256 – 6,270 of 60,541 results

6,256

Cayman Chemical A2AR AgonIst-1 500ug

An agonist of the adenosine A2A receptor and an inhibitor of ENT1 (Kis = 4.39 and 3.47 µM, for the human receptor and guinea pig transporter, respectively); decreases adenosine uptake by 80% in PC12 cells at 61 µM and increases brain levels of adenosine in a transgenic mouse model of Huntington’s disease at 20 mg/kg; rescues motor performance and increases survival in a transgenic mouse model of Huntington’s disease at 0.11 mg/kg

Pricing & Availability

6,257

Medchemexpress LLC 14-3-3 epsilon protein, mouse | 98.0% | 10 UG

Recombinant mouse 14-3-3 epsilon protein with an N-terminal 6xHis tag, expressed in Escherichia coli and supplied as a purified protein in a 10 μg vial. The protein has an expected molecular weight of ~31 kDa and is provided with QC documentation for research use in protein-protein interaction studies, antibody development, and assay setup.

Purity ≥98% as determined by reducing SDS-PAGE.
N-terminal 6xHis tag for affinity purification and detection.
Expressed in Escherichia coli to provide recombinant protein material.
Approximate molecular weight ~31 kDa for gel and mass confirmation.
Supplied as a low-quantity vial suitable for assay optimization and pilot studies.
Provided with COA/SDS documentation for traceability and handling.

Pricing & Availability

6,258

eMolecules 218600-44-3 | Bardoxolone | Advanced ChemBlocks - In Stock | MFCD07772296 | 491.672 | C31H41NO4 | 98.000 | CC1(C)CC[C@@]2(CC[C@]3(C)[C@@H]([C@@H]2C1)C(=O)C=C1[C@@]2(C)C=C(C#N)C(=O)C(C)(C)[C@@H]2CC[C@@]31C)C(O)=O | 100mg | 448693666

Bardoxolone | Advanced ChemBlocks - In Stock | 218600-44-3 | MFCD07772296 | 491.672 | C31H41NO4 | 98.000 | CC1(C)CC[C@@]2(CC[C@]3(C)[C@@H]([C@@H]2C1)C(=O)C=C1[C@@]2(C)C=C(C#N)C(=O)C(C)(C)[C@@H]2CC[C@@]31C)C(O)=O | 100mg | 448693666

Pricing & Availability

6,259

Cayman Chemical DOTATATE (acetate), Purity: ≥98%, CAS: 177943-89-4, 5 mg

A synthetic peptide; has been conjugated to various radioligands for use in scintigraphy and PET/CT imaging of SST-positive human tumor slices

Pricing & Availability

6,260

AdipoGen Cardamonin (25 mg)

Chemical. CAS: 19309-14-9. Formula: C16 H14 O4. MW: 270.28. Cardamonin is a calchone from Aplinia species (zingiberaceous plant species) with anti-cancer and anti-inflammatory, anti-nociceptive activity. Cardamonin suppresses NF-kappa nuclear translocation and Ik-Ba phosphorylation. It has been shown to suppress nitric oxide and prostaglandin E2 synthesis, to suppress cyclooxygenase-2 expression, and to inhibit NF-kappa signaling. It induces apoptosis in cancer cells, suppresses melanogenesis by inhibition of Wnt/beta-catenin signaling and ameliorates insulin resistance. It has been shown to induce autophagy and an antiproliferative effect through JNK activation. It is an hTRPA1 antagonist and shows also anti-parasitic activity. Also shown inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway.

Pricing & Availability

6,261

eMolecules 70-00-8 | Trifluridine | ChemScene | MFCD00006534 | 296.202 | C10H11F3N2O5 | 98.000 | OC[C@H]1O[C@H](C[C@@H]1O)n1cc(c(=O)[nH]c1=O)C(F)(F)F | 100mg | 536815489

Trifluridine | ChemScene | 70-00-8 | MFCD00006534 | 296.202 | C10H11F3N2O5 | 98.000 | OC[C@H]1O[C@H](C[C@@H]1O)n1cc(c(=O)[nH]c1=O)C(F)(F)F | 100mg | 536815489

Pricing & Availability

6,262

Medchemexpress LLC Clenbuterol hydrochloride | 21898-19-1 | 99.9% | 10 MM 1 ML

Clenbuterol hydrochloride is a selective β2-adrenergic agonist that enhances skeletal muscle strength and hypertrophy. It induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage.

Enhances skeletal muscle strength and hypertrophy.
Induces growth factor mRNA.
Activates astrocytes.
Protects rat brain tissue against ischemic damage.

Pricing & Availability

6,263

Medchemexpress LLC Thiacetazone (Thioacetazone; Amithiozone) | 104-06-3 | 99.7% | 1 ML

Thiacetazone (Thioacetazone) is a thiourea-containing antitubercular agent and an orally active antibiotic. It exhibits antibacterial action, inhibiting the growth of Mycobacterium tuberculosis H37Rv with a MIC value of 0.1 μg/mL. This product is a solution that is ready for reconstitution.

Antitubercular agent
Orally active antibiotic
Exhibits antibacterial action
Inhibits growth of Mycobacterium tuberculosis H37Rv
Ready for reconstitution solution

Pricing & Availability

6,264

Medchemexpress LLC 2-Hydroxy-4-(octyloxy)benzophenone | 1843-05-6 | 99.9% | 500 G

2-Hydroxy-4-(octyloxy)benzophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is intended for research use only and not for sale to patients.

Biochemical reagent for life science related research.
Available in solid form (white to yellow color).
Good purity of 99.91%.

Pricing & Availability

6,265

Cayman Chemical Parishin C, Purity: ≥95%, CAS: 174972-80-6, 10 mg

A phenolic glycoside; prevents Aβ42-induced inhibition of NMDAR currents in rat hippocampal neurons at 2 μM; prevents Aβ42-induced inhibition of LTP in rats at 20 mg/kg; a 5-HT1A receptor agonist (Ki = 1.54 nM; EC50 = 34 nM for [35S]GTPγS binding); reverses phencyclidine-induced increases in immobility time in the forced swim test, phencyclidine-induced decreases in interaction time in the social interaction test, and reverses phencyclidine-induced impairments in visual recognition of a novel object in mice

Pricing & Availability

6,266

Cayman Chemical 4-Methylumbelliferyl 2-Acetamido-2-deoxy-α-D-galactopyranoside, Purity: ≥98%, CAS: 124223-99-0, 5 mg

A fluorogenic substrate for α- and β-galactopyranosaminidase; is cleaved by α- and β-galactopyranosaminidase to release the fluorescent moiety 4-MU

Pricing & Availability

6,267

Cayman Chemical FIN56, Purity: ≥98%, CAS: 1083162-61-1, 5 mg

An inducer of ferroptosis; induces ferroptosis in BJ cells overexpressing oncogenic HRASG12V via acetyl-CoA carboxylase-dependent reduction in expression of GPX4 protein; binds to and activates squalene synthase in a GPX4 degradation-independent manner

Pricing & Availability

6,268

Cayman Chemical Ac-Nle-Pro-Nle-Asp-AMC (trifluoroacetate salt), Purity: ≥98%, 5 mg

A substrate for proteasomes (specific activities of 113 and 6.6 nmol/min/mg by the 26S (rabbit muscle) and 20S (yeast) proteasomes, respectively); cleaved by PGPH; allosterically inhibits the chymotrypsin-like activity of the proteasome

Pricing & Availability

6,269

Medchemexpress LLC Dutasteride methyl ester | 103335-41-7 | MFCD00876749 | 5mg

Dutasteride Impurity 1 is an impurity of Dutasteride (HY-13613)

Pricing & Availability

6,270

Medchemexpress LLC 9-acetyl-3,4-dihydro-2H-carbazol-1-one | 352553-42-5 | 99.8% | 227.26 g/mol | C14H13NO2 | 10 MG

MS7972 is a small-molecule inhibitor that disrupts the interaction between human p53 and CREB binding protein (CBP). It has been reported to nearly completely block this bromodomain (BRD) interaction at 50 μM and is supplied as a purified research compound for biochemical and cellular studies.

Blocks p53-CREB binding nearly completely at 50 μM.
Suitable for biochemical and cell-based assays.
High purity (99.81%) and characterized by NMR and HPLC.
Well-defined small-molecule structure: C14H13NO2, MW 227.26 g/mol.
Available in small-scale quantities for research use, including 10 MG packages.

Pricing & Availability

Bioactive Small Molecules

Filtered Search Results

Narrow Results

Medchemexpress LLC 14-3-3 epsilon protein, mouse | 98.0% | 10 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Clenbuterol hydrochloride | 21898-19-1 | 99.9% | 10 MM 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Thiacetazone (Thioacetazone; Amithiozone) | 104-06-3 | 99.7% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-Hydroxy-4-(octyloxy)benzophenone | 1843-05-6 | 99.9% | 500 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dutasteride methyl ester | 103335-41-7 | MFCD00876749 | 5mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 9-acetyl-3,4-dihydro-2H-carbazol-1-one | 352553-42-5 | 99.8% | 227.26 g/mol | C14H13NO2 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More