Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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616
Tocris Bioscience™ FC 11
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Highly potent focal adhesion kinase (FAK) Degrader (PROTAC™)
618
Tocris Bioscience™ MS 143
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and Specialty Supplier Partner
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AKT kinase Degrader (PROTAC™)
619
620
Tocris Bioscience™ CST 626
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent pan IAP Degrader (PROTAC™)
621
Tocris Bioscience™ 142D6
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Potent Lys-covalent pan-IAP inhibitor
622
Tocris Bioscience™ IRDye™ 680RD, NHS ester
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Near-infared dye (reactive group NHS ester)
623
Tocris Bioscience™ RMR-Tre
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Small and Specialty Supplier Partner
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Far-red fluorogenic trehalose probe for live mycobacteria imaging
624
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Thermo Scientific Chemicals Telaprevir
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Thermo Scientific Chemicals Telaprevir
CAS: 402957-28-2 Molecular Formula: C36H53N7O6
| CAS | 402957-28-2 |
|---|---|
| Molecular Formula | C36H53N7O6 |
625
Tocris Bioscience™ Autophinib
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent VPS34 inhibitor
626
Tocris Bioscience™ CBMR 0083
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Potent allosteric FFA1 (GPR40) and 4 (GPR120) agonist
| Target | Free Fatty Acid Receptor Agonists |
|---|---|
| CAS | 2839486-16-5 |
| Purity | 0.98 |
| Chemical Name or Material | 1-[3-[[4-Amino-6-[[2-(2,5-dichlorophenyl)ethyl]amino]-1,3,5-triazin-2-yl]methoxy]-5-methylphenyl]-2-pyrrolidinone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H24Cl2N6O2 |
627
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Thermo Scientific Chemicals Darunavir ethanolate
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Thermo Scientific Chemicals Darunavir ethanolate
CAS: 635728-49-3 Molecular Formula: C29H43N3O8S Molecular Weight (g/mol): 593.74 InChI Key: QWSHKNICRJHQCY-VBTXLZOXSA-N IUPAC Name: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-1-phenylbutan-2-yl]carbamate; ethanol SMILES: CCO.CC(C)CN(C[C@@H](O)[C@H](CC1=CC=CC=C1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)C1=CC=C(N)C=C1
| CAS | 635728-49-3 |
|---|---|
| Molecular Weight (g/mol) | 593.74 |
| SMILES | CCO.CC(C)CN(C[C@@H](O)[C@H](CC1=CC=CC=C1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)C1=CC=C(N)C=C1 |
| IUPAC Name | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-1-phenylbutan-2-yl]carbamate; ethanol |
| InChI Key | QWSHKNICRJHQCY-VBTXLZOXSA-N |
| Molecular Formula | C29H43N3O8S |
628
Tocris Bioscience™ CX08005
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Competitive PTP1B inhibitor
| CAS | 1256341-22-6 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-[[[2-(Tetradecyl)phenyl]amino]carbonyl]benzoic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C28H39N04 |
629
Atpenin A5, MP Biomedicals™
CAS: 119509-24-9 Molecular Formula: C15H21Cl2NO5 Molecular Weight (g/mol): 366.24 InChI Key: OVULNOOPECCZRG-CIUDSAMLSA-N Synonym: FO 125A5, atpenin A5, Antibiotic FO 125A5, Atpenin A5 (Synthetic), (2 S,4 S,5 R)-5,6-Dichloro-1-(2,4-dihydroxy-5,6-dimethoxypyridin-3-yl)-2,4-dimethyl-1-hexanone, (2 S,4 S,5 R)-1-(2,4-Dihydroxy-5,6-dimethoxy-3-pyridinyl)-2,4-dimethyl-5,6-dichloro-1-hexanone, 3-[(2 S,4 S,5 R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1 H)-pyridinone IUPAC Name: 3-[(2S,4S,5R)-5,6-dichloro-2,4-dimethylhexanoyl]-2-hydroxy-5,6-dimethoxy-1,4-dihydropyridin-4-one SMILES: COC1=C(OC)C(=O)C(C(=O)[C@@H](C)C[C@H](C)[C@@H](Cl)CCl)=C(O)N1
| CAS | 119509-24-9 |
|---|---|
| Molecular Weight (g/mol) | 366.24 |
| SMILES | COC1=C(OC)C(=O)C(C(=O)[C@@H](C)C[C@H](C)[C@@H](Cl)CCl)=C(O)N1 |
| Synonym | FO 125A5, atpenin A5, Antibiotic FO 125A5, Atpenin A5 (Synthetic), (2 S,4 S,5 R)-5,6-Dichloro-1-(2,4-dihydroxy-5,6-dimethoxypyridin-3-yl)-2,4-dimethyl-1-hexanone, (2 S,4 S,5 R)-1-(2,4-Dihydroxy-5,6-dimethoxy-3-pyridinyl)-2,4-dimethyl-5,6-dichloro-1-hexanone, 3-[(2 S,4 S,5 R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1 H)-pyridinone |
| IUPAC Name | 3-[(2S,4S,5R)-5,6-dichloro-2,4-dimethylhexanoyl]-2-hydroxy-5,6-dimethoxy-1,4-dihydropyridin-4-one |
| InChI Key | OVULNOOPECCZRG-CIUDSAMLSA-N |
| Molecular Formula | C15H21Cl2NO5 |
630
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Thermo Scientific Chemicals Tazarotene
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Thermo Scientific Chemicals Tazarotene
CAS: 118292-40-3 Molecular Formula: C21H21NO2S
| CAS | 118292-40-3 |
|---|---|
| Molecular Formula | C21H21NO2S |