Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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616
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630
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60,533
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617
R&D Systems™ VH 032, thiol
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Functionalized VHL ligand for PROTAC™; development
618
R&D Systems™ PRX 07034
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective 5-HT6 receptor antagonist (IC50 = 19 nM, Ki = 4 to 8 nM)
| CAS | 903580-39-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-(1-(5-Chloro-2,3-dimethoxyphenyl)ethyl)-2-(methylsulfonyl)-5-(piperazin-1-yl)aniline hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H28ClN3O4S.HCl |
| Formula Weight | 490.44 |
619
R&D Systems™ CBMR 0083
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent allosteric FFA1 (GPR40) and 4 (GPR120) agonist
| Target | Free Fatty Acid Receptor Agonists |
|---|---|
| CAS | 2839486-16-5 |
| Purity | 0.98 |
| Chemical Name or Material | 1-[3-[[4-Amino-6-[[2-(2,5-dichlorophenyl)ethyl]amino]-1,3,5-triazin-2-yl]methoxy]-5-methylphenyl]-2-pyrrolidinone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H24Cl2N6O2 |
620
R&D Systems™ A 410099.1 amide-PEG2-amine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. IAP ligand with PEG linker and terminal amine for onward chemistry
621
R&D Systems™ Obatoclax Mesylate
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Inhibitor of Bcl-2 family members (IC50 values are 1.11 - 7 μM); antiapoptotic
| CAS | 803712-79-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate |
| Recommended Storage | Store at -20°C |
| Synonym | GX15-070 |
| Molecular Formula | C20H19N3O.CH3SO3H |
| Formula Weight | 413.49 |
622
R&D Systems™ SPOP-i-6lc
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. SPOP E3 ubiquitin ligase inhibitor
623
R&D Systems™ RMR-Tre
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Far-red fluorogenic trehalose probe for live mycobacteria imaging
624
R&D Systems™ ARN 3236
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent inhibitor of salt-inducible kinases
| Target | SNF1LK2/SIK2 |
|---|---|
| CAS | 1613710-01-2 |
| Purity | 0.98 |
| Chemical Name or Material | 3-(2,4-Dimethoxyphenyl)-4-(3-thienyl)-1 H-pyrrolo[2,3-b]pyridine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H16N2O2S |
625
R&D Systems™ Z 944
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. CaV3.x blocker
| CAS | 1199236-64-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-[[(3-Chloro-5-fluorobenzoyl)amino)methyl]-N-(1,1-dimethylethyl)-1-piperidineacetamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C19H27ClFN3O2 |
| Formula Weight | 383.89 |
626
R&D Systems™ GSK'872
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective RIP3 kinase inhibitor
| CAS | 1346546-69-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-5-Benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H17N3O2S2 |
| Formula Weight | 383.49 |
627
R&D Systems™ T4
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3
| Target | DNA, RNA and Protein Synthesis Compounds |
|---|---|
| CAS | 785708-33-0 |
| Purity | 0.98 |
| Chemical Name or Material | 6,7-Dimethoxy-2-[((4-phenyl-3,6-dihydropyridin-1(2 H)-yl)methyl)]quinazolin-4(3 H)-one |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H23N3O3 |
628
R&D Systems™ 5-InoAz
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Metabolic probe for labeling mycobacterium cell envelope
| Target | Glycobiology Probes |
|---|---|
| CAS | 1218932-97-8 |
| Purity | 0.9 |
| Chemical Name or Material | 5-Azido-5-deoxy-myo-inositol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C6H11N3O5 |
629
R&D Systems™ GSK 2239633A
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent CCR4 antagonist
| CAS | 1240516-71-5 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[[3-[[3-[[(5-Chloro-2-thienyl)sulfonyl]amino]-4-methoxy-1H-indazol-1-yl]methyl]phenyl]methyl]-2-hydroxy-2-methylpropanamide |
| Molecular Formula | C24H25ClN4O5S2 |
