Bioactive Small Molecules
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Filtered Search Results
Medchemexpress LLC 2,5-Dihydroxybenzoic acid | 490-79-9 | 154.12 | 500 MG
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2,5-Dihydroxybenzoic acid, also known as Gentisic acid, is a benzoic acid derivative and a potent inhibitor of fibroblast growth factors. This compound is also a byproduct of aspirin metabolism and found in traditional remedies. It serves as a valuable lead for developing new fibroblast growth factor inhibitors, which may be useful in treating cancer and angiogenesis-dependent diseases.
- Derivative of benzoic acid
- Potent inhibitor of fibroblast growth factors
- Metabolic breakdown product of aspirin
- Component of traditional liquors and herbal remedies
- Used as a lead for new fibroblast growth factor inhibitors
- May be of interest to treat cancer and angiogenesis-dependent diseases
- Solid appearance
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Cayman Chemical Aspulvinone O, Purity: ≥85%, CAS: 914071-54-8, 5 mg
A fungal metabolite; scavenges DPPH radicals in a cell-free assay (IC50 = 11.6 µM); inhibits GOT1 (Kd = 3.32 µM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (IC50s = 20.54-26.8 µM); reduces the OCR and induces apoptosis in SW1990 cells; reduces tumor growth in an SW1990 mouse xenograft model at 2.5 and 5 mg/kg
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Selleck Chemical LLC Cediranib S1017-5MG
Cediranib (AZD2171 NSC-732208) is a highly potent VEGFR(KDR) inhibitor with IC50 of 1 nM also inhibits Flt1/4 with IC50 of 5 nM/ 3 nM similar activity against c-Kit and PDGFR 36- 110-fold and 1000-fold selective more for VEGFR than PDGFR- CSF-1R and Flt3 in HUVEC cells Cediranib (AZD2171) induces autophagic vacuole accumulation Phase 3
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Apexbio Technology LLC Hydroxyurea, 5g. Cas: 127-07-1 MFCD: MFCD00007943. DNA synthesis inhibitor
Hydroxyurea 10mg. 83602-39-5. MFCD04039488 Hydroxyurea There are other sizes available. Please inqury us for quote.
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Apexbio Technology LLC Propylthiouracil, 500mg Cas# 51-52-5
Propylthiouracil 10mg. 1316215-12-9. MFCD28023593 Propylthiouracil There are other sizes available. Please inqury us for quote.
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Cayman Chemical Clomazone, Purity: ≥95%, CAS: 81777-89-1, 50 mg
An herbicide that reduces chlorophyll and carotenoid levels in plants; used to control grasses and broad-leaved weeds; toxic to certain aquatic wildlife (LC50 = 7.32 mg/L for silver catfish); decreases AChE activity in brain and muscle tissue of the silver catfish (83 and 89% inhibition, respectively) when used at concentrations of 5, 10, and 20 mg/L; increases AChE activity in teleost fish muscle
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Cayman Chemical 1,3-Dinervonoyl Glycerol, Purity: ≥98%, CAS: 960594-30-3, 5 mg
A diacylglycerol that contains nervonic acid at the sn-1 and sn-3 positions
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Cayman Chemical HhAntag, Purity: ≥95%, CAS: 496794-70-8, 1 mg
A hedgehog pathway inhibitor (EC50 = 0.4 μM for Shh signaling in a reporter assay); inhibits proliferation of GNP cells from 0.1 nM to 25 μM; suppresses Gli1 mRNA levels and increases tumor cell death in a mouse model of Ptc1+/-p53-/- medulloblastoma at 20 and 100 mg/kg; blocks basal and bone morphogenic protein 2-induced chondrogenesis in micromass cultures of mouse limb mesenchymal cells
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Cayman Chemical LysoFP-NO2, Purity: ≥98%, CAS: 69408-75-9, 5 mg
A turn-on lysosome-targeted fluorescent probe for CO; transformed into the highly fluorescent derivative lysoFP-NH2 in the presence of lysosomal CO; selective for CO over reactive nitrogen, oxygen, and sulfur species; ex/em = 440/528 nm, respectively; not cytotoxic to HepG2 cells for up to five hours at 30 µM
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![Medchemexpress LLC 9-(8-azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic acid diethylamide | 825649-28-3 | 98.1% | 388.50 g/mol | C25H28N2O2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000263604.png-250.jpg)
Medchemexpress LLC 9-(8-azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic acid diethylamide | 825649-28-3 | 98.1% | 388.50 g/mol | C25H28N2O2 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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JNJ-20788560 is a small-molecule research compound that acts as a selective and orally active delta opioid receptor (DOR) agonist, used in preclinical pharmacology studies of analgesia and inflammatory hyperalgesia.
- Selective delta opioid receptor agonist with high affinity (≈2.0 nM).
- Suitable for preclinical analgesia and inflammatory hyperalgesia research.
- High purity solid (≈98.1%).
- Molecular formula C25H28N2O2; molecular weight 388.50 g/mol.
- Powder stable at -20°C for long-term storage; limited stability in solution.
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Medchemexpress LLC Ethanone, 1-(2,5-dihydroxyphenyl)- | 490-78-8 | 152.15 | 1 G
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2,5-Dihydroxyacetophenone is isolated from Rehmannia glutinosa and functions by inhibiting the production of inflammatory mediators in activated macrophages. It primarily achieves this by blocking the ERK1/2 and NF-κB signaling pathways. This compound is intended for research use only and is not suitable for patient applications.
- Inhibits NO production through suppression of iNOS expression
- Decreases levels of pro-inflammatory cytokines such as TNF-α and IL-6
- Blocks ERK1/2 and NF-κB signaling pathways
- Potently inhibits the phosphorylation of extracellular signal-related kinase (ERK) 1/2
- Potently inhibits the nuclear translocation of nuclear factor-κB (NF-κB) p65
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Cayman Chemical Azelastine (hydrochloride), Purity: ≥98%, CAS: 79307-93-0, 5 mg
A histamine H1 receptor antagonist (Ki = 1.26 nM); selective for histamine H1 over histamine H3 receptors (Ki = 158.49 nM), as well as α1A- and α1B-adrenergic receptors (Ki = 50.12 nM for both); reduces nose rubbing, sneezing, and nasal mucosa expression of IL-4 in a dust mite-induced mouse model of allergic rhinitis at 0.14 µg/animal; reduces infection by a lentivirus pseudotyped with SARS-CoV-2 spike glycoprotein in HEK293 cells expressing ACE2 at 7 µg/ml
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Medchemexpress LLC 3-Chlorogentisyl alcohol | 32744-80-2 | C7H7ClO3 | 5 MG
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3-Chlorogentisyl alcohol is a potent E. coli β-glucuronidase inhibitor. It exhibits antiproliferative activity and holds potential for research in anti-cancer and anti-inflammatory therapies.
- Potent β-glucuronidase inhibitor
- Exhibits antiproliferative activity
- Potential for anti-cancer research
- Potential for anti-inflammatory research
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Medchemexpress LLC Pimelic acid | 111-16-0 | MFCD00004425 | ≥98.0% | 160.17 g/mol | C7H12O4 | 5g
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Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine Pimelic acid can be used in keratoconus research[1]
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STEMCELL Technologies plus-MK-801 Hydrogen Maleate
NMDA antagonist - 10 Mg
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