Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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6,466 – 6,480 of 60,541 results

6,466

Medchemexpress LLC Sodium thiocyanate, GR | 540-72-7 | 99.1% | 81.07 | 50 G

Sodium thiocyanate reduces plasma levels of the pro-inflammatory cytokine IL-6 and increases the anti-inflammatory cytokine IL-10 levels. It also significantly reduces ROS formation.

Reduces pro-inflammatory cytokine IL-6
Increases anti-inflammatory cytokine IL-10
Significantly reduces ROS formation

Pricing & Availability

6,467

Medchemexpress LLC Hydrogenated soya phosphatidylcholine | 97281-48-6 | 99.3% | 790.16 | 100 MG

Hydrogenated soya phosphatidylcholine is a natural product that can extend drug release concerning drug loading and solubility for oral drug delivery of water-soluble drugs.

Can achieve 80% encapsulation rate of Oxymatrine (HY-N0158) in vitro.
Can significantly prolong the half-life of Oxymatrine, improve its bioavailability, enhance liver targeting, reduce liver damage, and promote liver recovery in vivo.

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6,468

Medchemexpress LLC APP-018 (D-4F) | 452782-06-8 | 99.8% | 2310.60 | 5 MG

APP-018 (D-4F) | 452782-06-8 | 99.8% | 2310.60 | 5 MG

Pricing & Availability

6,469

Medchemexpress LLC Olitigaltin | 1450824-22-2 | 99.7% | 648.64 | 1 ML

Olitigaltin (TD139) is a synthetic galectin-3 inhibitor with a high affinity for galectin-3, galectin-1, and galectin-7. It is intended for research use only. This product is provided as a 10 mM solution in DMSO, ready for reconstitution or direct use.

High affinity galectin-3 inhibitor
Targets galectin-1 and galectin-7
Provided as a 10 mM solution
Suitable for research use

Pricing & Availability

6,470

Medchemexpress LLC BMS-345541 hydrochloride | 547757-23-3 | 99.9% | 291.78 g·mol⁻¹ | C14H18ClN5 | 10 MM 1 ML

BMS-345541 hydrochloride is a selective small-molecule inhibitor of the catalytic subunits of IκB kinase (IKK). It binds at an allosteric site and preferentially inhibits IKK-2 (IC50 0.3 μM) over IKK-1 (IC50 4 μM). The compound is supplied for research use and is available as a solid or as a 10 mM solution in DMSO.

Selective inhibition of IκB kinase catalytic subunits.
Allosteric binding mechanism provides distinct mode of action.
Potent IKK-2 inhibition (IC50 0.3 μM).
High reported purity (≈99.9%).
Available as solution in DMSO and multiple solid sizes for experimental flexibility.
Intended for research use only.

Pricing & Availability

6,471

Medchemexpress LLC GSK8612 | 2361659-62-1 | 99.6% | 520.33 | 1 MG

GSK8612 is a highly selective and potent Tank-binding Kinase-1 (TBK1) inhibitor, with a pIC50 of 6.8 for recombinant TBK1. It inhibits toll-like receptor (TLR)3-induced IRF3 phosphorylation in Ramos cells and type I IFN secretion in primary human mononuclear cells. In THP1 cells, GSK8612 inhibits secretion of IFNβ in response to dsDNA and cGAMP, the natural ligand for STING.

Highly selective and potent TBK1 inhibitor
Inhibits TLR3-induced IRF3 phosphorylation
Inhibits type I IFN secretion in primary human mononuclear cells
Inhibits secretion of IFNβ in response to dsDNA and cGAMP in THP1 cells

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6,472

Selleck Chemical LLC Vismodegib (GDC-0449) 5mg 879085-55-9

Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 ?M in a cell-free assay. *For Research & Development use only. Product is not intended for drug, household, or human consumption.

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6,473

Medchemexpress LLC HY-10518 50mg Medchemexpress, BMS-345541 BMS-345541 hydrochloride CAS:547757-23-3 Purity:98%

Medchemexpress,HY-10518 50mg BMS-345541 BMS-345541 hydrochloride CAS:547757-23-3 Formula:C14H18ClN5 BMS-345541 is a selective inhibitor of the catalytic subunits of IKK (IKK-2 IC50=0.3 μM, IKK-1 IC50=4 μM). BMS-345541 binds at an allosteric site of IKK. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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6,474

AdipoGen 4-Fluoro-2 1 3-benzoxadiazol

Chemical. CAS 29270-55-1. Formula C6H3FN2O. MW 138.1. Synthetic. 4-Fluoro-2,1,3-benzoxadiazole is a fluorescent benzofurazan derivative.

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6,475

AdipoGen -Potassium citramalate H2O

Chemical. CAS 1030365-02-6. Formula C5H6O5 . 2K . H2O. MW 146.1 . 78.2 . 18.0. Synthetic Building block for synthesis.

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6,476

AdipoGen ZnAF-1F DA

Chemical. Formula C38H30F2N4O7. MW 692.66. Synthetic. For application to living cells, the diacetyl derivative of ZnAF-1F, ZnAF-1F DA, was synthesized. ZnAF-1F DA can permeate through the cell membrane, and is hydrolyzed by esterase in the cytosol to yield ZnAF-1F, which is retained in the cells. ZnAF-1F DA has been used to measure the changes of intracellular Zn2 in cultured cells and hippocampal slices. Spectral data lambdaex 492nm lambdaem 514nm in PBS.

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6,477

AdipoGen Pyrenetetrasulfonic acid 4Na

Chemical. CAS 59572-10-0. Formula C16H6Na4O12S4 . xH2O. MW 610.43 anhydrous basis. Synthetic Fluorescent probe and pH indicator. It fluoresces blue in acidic solutions and in acidic organelles but fluoresces green in more basic organelles. This compound is potentially useful as a coloring agent, biological stain or optical detecting reagent. It is used in water-in-oil-in-water emulsions and as a substrate for lipase activity. Spectral data lambdaex 375nm, lambdaem 404nm in water.

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6,478

MSC AbilityOne Wet Mop Head, Looped-End, Anti-Microbial, 20 oz, White, 12/Bx

These premium mop heads feature new and improved antimicrobial yarns with FOSSHIELD™, a naturally safe, silver and copper ion infused fiber protected with AgION™ technology. This technology prevents the growth of bacteria, mold, and mildew while reducing odors.

Looped-end, 4-ply construction of rayon, acrylic, and recycled PET polyester fibers
Features a 5-1/2 in nylon mesh headband with six main sews and pre-shrunk tailbands
Offers superior wear, absorbency, and performance
Washable
Comes 12 per box

Pricing & Availability

6,479

Medchemexpress LLC 2,5-Dihydroxybenzoic acid | 490-79-9 | MFCD00002476 | 154.12 | 1 G

2,5-Dihydroxybenzoic acid, also known as Gentisic acid, is a benzoic acid derivative and a potent inhibitor of fibroblast growth factors. It is recognized as a minor metabolite of aspirin and a constituent in various traditional liquors and herbal remedies. This compound serves as a critical lead in the discovery of new chemical classes of fibroblast growth factor inhibitors.

Derivative of benzoic acid
Potent inhibitor of fibroblast growth factors
Minor product of aspirin's metabolic breakdown
Component of traditional liquors and herbal remedies
Used as a lead to identify new fibroblast growth factor inhibitors
May interfere with assembly of signaling complexes for fibroblast growth factor-driven mitogenesis
Potential interest for treating cancer and angiogenesis-dependent diseases

Pricing & Availability

6,480

Medchemexpress LLC 4-Chloroindole-3-acetic acid (4-Cl-IAA) | 2519-61-1 | 209.63 | 500 MG

4-Chloroindole-3-acetic acid (4-Cl-IAA) | 2519-61-1 | 209.63 | 500 MG

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Bioactive Small Molecules

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Medchemexpress LLC Sodium thiocyanate, GR | 540-72-7 | 99.1% | 81.07 | 50 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Hydrogenated soya phosphatidylcholine | 97281-48-6 | 99.3% | 790.16 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC APP-018 (D-4F) | 452782-06-8 | 99.8% | 2310.60 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Olitigaltin | 1450824-22-2 | 99.7% | 648.64 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BMS-345541 hydrochloride | 547757-23-3 | 99.9% | 291.78 g·mol⁻¹ | C14H18ClN5 | 10 MM 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC GSK8612 | 2361659-62-1 | 99.6% | 520.33 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-10518 50mg Medchemexpress, BMS-345541 BMS-345541 hydrochloride CAS:547757-23-3 Purity:98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2,5-Dihydroxybenzoic acid | 490-79-9 | MFCD00002476 | 154.12 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 4-Chloroindole-3-acetic acid (4-Cl-IAA) | 2519-61-1 | 209.63 | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More