Bioactive Small Molecules
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (16)
- (2)
- (2)
- (2)
- (27)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (153)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (5)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (5)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (96)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (52)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (25)
- (9)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (63)
- (1)
- (2)
- (5)
- (271)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (7)
- (6)
- (1)
- (2)
- (2)
- (1)
- (3)
- (1)
- (91)
- (16)
- (8)
- (2)
- (9)
- (4)
- (2)
- (1)
- (3)
- (4)
- (2)
- (15)
- (2)
- (1)
- (7)
- (2)
- (4)
- (2)
- (2)
- (1)
- (2)
- (6)
- (1)
- (7)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
Filtered Search Results
Cayman Chemical Diphyllin, Purity: ≥98%, CAS: 22055-22-7, 5 mg
A lignan with diverse biological activities; reduces viral titers in SARS-CoV-2-infected Vero cells (EC50 = 1.92 µM); inhibits bovine chromaffin granule V-ATPase (IC50 = 17 nM) and lysosomal acidification in primary human osteoclasts; induces apoptosis in and inhibits the growth of SGC-7901 cells at 1, 5, and 10 µM; reduces intratumoral expression of V-ATPase and tumor volume in an SGC-7901 mouse xenograft model at 20 mg/kg
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC GSK1016790A 942206-85-1 25mg
GSK1016790A (CAS 942206-85-1) is a potent small molecule agonist of the transient receptor potential vanilloid 4 (TRPV4) channel a Ca2 -permeable nonselective cation channel involved in diverse physiological processes including osmoregulation vascular tone skin integrity airway function and nociception GSK1016790A induces Ca2 influx in TRPV4-expressing mouse and human embryonic kidney (HEK) cells with EC50 values of 18 nM and 2 1 nM respectively and elicits dose-dependent activation of TRPV4 whole-cell currents In ex vivo mouse bladder models it triggers contractions and bladder overactivity through TRPV4 activation GSK1016790A is widely used to probe TRPV4-mediated signaling in cellular and physiological studies
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
![eMolecules 175865-59-5 | 2-[(2-Amino-6-oxo-6,9-dihydro-1H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-amino-3-methylbutanoate hydrochloride | Combi-Blocks, Inc. | MFCD08460118 | 390.830 | C14H23ClN6O5 | 98.000 | Cl.CC(C)[C@H](N)C(=O)OCC(CO)OCn1cnc2c1nc(N)[nH]c2=O | 1g | 586077664](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502186846.JPG-250.jpg)
eMolecules 175865-59-5 | 2-[(2-Amino-6-oxo-6,9-dihydro-1H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-amino-3-methylbutanoate hydrochloride | Combi-Blocks, Inc. | MFCD08460118 | 390.830 | C14H23ClN6O5 | 98.000 | Cl.CC(C)[C@H](N)C(=O)OCC(CO)OCn1cnc2c1nc(N)[nH]c2=O | 1g | 586077664
2-[(2-Amino-6-oxo-6,9-dihydro-1H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-amino-3-methylbutanoate hydrochloride | Combi-Blocks, Inc. | 175865-59-5 | MFCD08460118 | 390.830 | C14H23ClN6O5 | 98.000 | Cl.CC(C)[C@H](N)C(=O)OCC(CO)OCn1cnc2c1nc(N)[nH]c2=O | 1g | 586077664
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Cayman Chemical Carbidopa-d3 (hydrate), Purity: ≥99% deuterated forms (d1-d3), CAS: 1276197-58-0, 5 mg
An internal standard for the quantification of carbidopa by GC- or LC-MS
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
TARGETMOL CHEMICALS INC NECROX-5 5MG
502694186 NECROX-5 5MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
TARGETMOL CHEMICALS INC SGN-2FF 5MG
502694178 SGN-2FF 5MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Cayman Chemical Agonodepside B, Purity: ≥95%, CAS: 445298-41-9, 5 mg
A fungal metabolite.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Diethyl phosphate | 598-02-7 | MFCD00039889 | 98.1% | 154.10 g/mol | C4H11O4P | 10 G
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Diethyl phosphate is an organophosphorus reagent (diethyl phosphoric acid) used as a laboratory reagent and analytical standard. It is used in metabolite analysis, chemical synthesis, and as a reference standard for analytical methods. Consult the safety data sheet for hazard classifications, protective measures, and recommended storage conditions.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC BMS-192364 50mg | 202822-21-7 | 355.70 g·mol⁻¹ | C15H9ClF3N3O2 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
BMS-192364 is a small-molecule research compound described as an RGS (regulator of G-protein signaling) agonist. It modulates Gα-RGS interactions and alters calcium flux, and has been used in studies of urinary bladder contraction and G-protein-coupled signaling pathways. Supplied as a high-purity 50 mg vial for research applications.
- Targets Gα-RGS interaction as an RGS agonist.
- Modulates calcium signaling and reduces bladder contraction in models.
- Molecular formula C15H9ClF3N3O2.
- Molecular weight 355.70 g·mol⁻¹.
- Supplied purity 99.01% and packaged as 50 mg.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Histamine dihydrochloride (Standard) | 56-92-8 | 99.96% | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Histamine dihydrochloride (Standard) | 56-92-8 | 99.96% | 100 MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC XAV-939 (GMP) | 284028-89-3 | C14H11F3N2OS | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
XAV-939 (GMP) is a tankyrase inhibitor produced using GMP guidelines. It functions as an auxiliary reagent for cell therapy manufacture and induces human pluripotent stem cells (hPSCs) to differentiate into post-mitotic cortical neurons, promoting anterior CNS identity.
- Functions as an auxiliary reagent for cell therapy manufacture
- Induces human pluripotent stem cells (hPSCs) to post-mitotic cortical neurons differentiation
- Promotes anterior CNS identity
- Tankyrase inhibitor
- Produced using GMP guidelines
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC HDAC6-IN-13 | 2837128-41-1 | C23H22N4O | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
HDAC6-IN-13 (Compound 35m) is a potent, highly selective, orally active HDAC6 inhibitor with an IC50 of 0.019 μM. It also inhibits HDAC1, HDAC2, and HDAC3 with IC50s of 1.53, 2.06, and 1.03 μM, respectively. This compound demonstrates significant BBB permeability and anti-inflammatory activity.
- Potent and highly selective HDAC6 inhibitor.
- Exhibits significant blood-brain barrier permeability.
- Demonstrates anti-inflammatory activity.
- Slow-on and slow-off tight-binding HDAC6 inhibitor.
- High oral bioavailability (F% = 93.4%) in mice.
- Inhibits LPS-induced inflammation in mice.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC ACT-660602 | 1646267-59-5 | C20H20F6N8OS | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
ACT-660602 is an orally active antagonist of chemokine receptor (CXCR3) with an IC50 value of 204 nM. It inhibits T-cell migration and shows efficacy in an acute lung injury model, making it suitable for autoimmune disease research.
- Inhibits T-cell migration
- Shows efficacy in an acute lung injury model
- Selective for CXCR3 over hERG (IC50 of 18 μM for hERG)
- Enhances metabolic stability
- Displays non-competitive binding mode to CXCL10 and CXCL11
- Exhibits anti-inflammatory activity
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Cayman Chemical GDC-1971, Purity: ≥98%, CAS: 2377352-49-1, 5 mg
An SHP-2 inhibitor (IC50 = E76K (IC50 = 0.17 µM); reduces the levels of phosphorylated ERK in a reporter assay using KYSE-520 cancer cells (IC90 = 0.012 µM) and inhibits proliferation of the same cells (IC50 = 0.32 µM); reduces tumor volume in KYSE-520 and NCI H358 mouse xenograft models at 30 or 100 mg/kg two times per day
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Reparixin | 266359-83-5 | C14H21NO3S | 2 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation. It effectively inhibits CXCL8-induced biological activities on human PMNs, showing significant selectivity for CXCR1. This compound has been demonstrated to mitigate inflammatory responses across various injury models.
- Non-competitive allosteric inhibitor of chemokine receptors CXCR1 and CXCR2
- Potent functional inhibitor of CXCL8-induced biological activities
- Attenuates inflammatory responses in various injury models
- Decreases systolic blood pressure and increases blood flow in spontaneously hypertensive rats
- Reduces IL-1β levels in the brain after middle cerebral artery occlusion/reperfusion in mice
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More