Bioactive Small Molecules
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Filtered Search Results
Medchemexpress LLC Coumarin 6H | 58336-35-9 | 99.6% | 100MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Coumarin 6H | 58336-35-9 | 99.6% | 100MG
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Cayman Chemical A-740003, Purity: ≥98%, CAS: 861393-28-4, 25 mg
A selective P2X7 antagonist (IC50s = 40 and 18 nM for human and rat receptors, respectively); blocks agonist-induced IL-1β release and pore formation in differentiated THP-1 cells (IC50s = 156 and 92 nM, respectively); effective in vivo when administered intraperitoneally
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Medchemexpress LLC Morin | 480-16-0 | MFCD22573212 | 302.24 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Morin | 480-16-0 | MFCD22573212 | 302.24 | 25 MG
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Cayman Chemical Chartreusin, Purity: ≥98%, CAS: 6377-18-0, 5 mg
An antibiotic with diverse biological activites; inhibits growth of S. aureus, B. subtilis, M. luteus, M. flavus, B. fragilis, C. difficile, C. perfringens, and P. acnes (MICs = 0.4-12.5 μg/ml); inhibits strand-passing activity of topoisomerase II in a P4 unknotting assay; inhibits protein synthesis in CEFs and 3T6 cells (IC50s = 7 and 70 μM, respectively); cytotoxic to human lung carcinoma A549 cells in vitro (IC50 = 95 nM); increases median survival in P388 leukemia and B16 melanoma mouse tumor models (10 mg/kg per day)
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Medchemexpress LLC HY-N0837 5mg Medchemexpress, Veratramine CAS:60-70-8 Purity:>98%
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Medchemexpress, HY-N0837 5mg Veratramine CAS:60-70-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC Z-LEHD-FMK TFA 2mg 524746-03-0 Caspase-9 Inhibitor
Z-LEHD-FMK TFA (Caspase-9 Inhibitor) is a cell-permeable, competitive and irreversible inhibitor of enzyme caspase-9, which helps in cell survival. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC Selumetinib sulfate E6024-50MG
Selumetinib sulfate (AZD6244 sulfate ARRY-142886 sulfate) is an oral non-ATP-competitive inhibitor of MEK1/2 with an IC50 of 14 nmol/L against purified MEK1 It exhibits an anti-tumor effect in the HT-29 xenograft model and is used to treat cancer and inflammation
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Selleck Chemical LLC Ifenprodil E4881-1G
Ifenprodil(Dilvax RC 61-91) is a potent antagonist of N-methyl-D-aspartate (NMDA) receptor that selectively inhibits receptors containing the NR2B subunit It exhibits potential for its use in the treatment of various neurological diseases
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Cayman Chemical EHop-016, Purity: ≥98%, CAS: 1380432-32-5, 10 mg
A Rac1 and Rac3 inhibitor; inhibits Rac1 activity (IC50 = 1.1 μM); inhibits Rac3 activity (58% at 1 μM); inhibits Cdc42 activity (28% at ≥ 5 μM); increases RhoA activity (1.3-fold at ≥2 μM); increases Rac-regulated lamellipodia formation and PAK1-mediated cell migration in MDA-MB-435 cells (2-4 μM); lowers mammary fat pad tumor growth, metastasis, and angiogenesis in a nude mouse model of breast cancer (25 mg/kg); inhibits mutant KIT-induced growth in systemic mastocytosis and AML cells (≥2.5 μM)
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Selleck Chemical LLC TD-139 5mg
TD-139 (GB0-139) is a potent and selective inhibitor ofgalectin-3 with Kd of 0.036 ¿¿ over galectin-1 and galectin-7 with Kd of 2.2 ¿¿ and 32 ¿¿, respectively. TD-139 is used potentially for the treatment of idiopathic pulmonary fibrosis (IP *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Medchemexpress LLC HY-50904 100mg , Nintedanib CAS:656247-17-5 Purity:>98%
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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HY-50904 100mg Nintedanib CAS: 656247-17-5 Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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TARGETMOL CHEMICALS INC DIHYDROSANGUINARINE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Dihydrosanguinarine is a natural compound isolated from the leaves of Macleaya microcarpaand has antifungal and anticancer activity. purity: 99%
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Cayman Chemical Dianemycin, Purity: ≥95%, CAS: 35865-33-9, 25 mg
A polyether ionophore antibiotic; has insecticidal and antibacterial properties; blocks ZIKV entry into U2OS, human microvascular endothelial cells, and placental Jeg3 cells (IC50s = 100, 400, and 970 nM, respectively); blocks ZIKV entry into certain primary cells; effective against West Nile, dengue, Sindbis, and chikungunya viruses in U2OS cells
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Selleck Chemical LLC FN-1501 E2658-5MG
FN-1501 is a potent inhibitor of Fms-like receptor tyrosine kinase 3 (FLT3) and cyclin-dependent kinase (CDK) with IC50s of 2 47 0 85 1 96 and 0 28 nM for CDK2/cyclin A CDK4/cyclin D1 CDK6/cyclin D1 and FLT3 respectively
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Selleck Chemical LLC Mitoguazone E7797-5MG
Mitoguazone is a polyamine analog that disrupts polyamine biosynthesis by inhibiting S-adenosylmethionine decarboxylase (SAMDC) It induces apoptosis and triggers p53-independent programmed cell death in the MCF7 cell line It also inhibits the integration of HIV DNA into cellular DNA in both monocytes and macrophages
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