Bioactive Small Molecules
American Research Products Inc Anti KLK2 Ab JNJ 69086420
Anti-Human KLK2 Antibody (JNJ-69086420) Research Grade
Medchemexpress LLC Etoposide | 33419-42-0 | MFCD00869325 | 99.6% | 588.56 g/mol | C29H32O13 | 5 MG
Etoposide (Standard) is an analytical reference material of the chemotherapeutic compound etoposide provided as a high-purity material for research and analytical applications. It is intended for method development, calibration, and qualitative or quantitative assays in laboratories.
Medchemexpress LLC Agatolimod (ODN 2006) | 525625-52-9 | 96.7% | 7699.00 g/mol | C238H314N75O127P23S23 | 5 MG
Agatolimod (ODN 2006) is a class B oligodeoxynucleotide TLR9 agonist containing an optimized CpG motif. It is used as a research reagent to stimulate innate immune responses, induce cytokine production, and support preclinical immuno-oncology studies.
- Sequence: 5'-tcgtcgttttgtcgttttgtcgtt-3'.
- Molecular weight: 7,699 g/mol (manufacturer value).
- Purity: 96.73% (product-level listing).
- Solubility: water ≥125 mg/mL.
- Storage: sealed, away from moisture; short-term 4°C; in solvent -80°C for long term.
- Applications: TLR9 activation, cytokine induction, preclinical immuno-oncology research.
Medchemexpress LLC Dtagv-1-neg | 2451573-87-6 | 99.7% | 1247.54 g/mol | C68H90N6O14S | 5 MG
dTAGV-1-NEG is a diastereomeric heterobifunctional negative control compound used in targeted protein degradation studies of FKBP12(F36V). It is supplied as a high-purity research reagent for biochemical and cellular assays.
Medchemexpress LLC Malonyl coenzyme A lithium | 108347-84-8 | MFCD00057769 | 98.0% | 860.6 g/mol | C24H38LiN7O19P3S | 5 MG
Malonyl CoA lithium is the lithium salt form of malonyl coenzyme A used as a biochemical reagent to modulate mitochondrial fatty acid metabolism. It functions as an inhibitor of carnitine palmitoyl transferase 1 (CPT1) and is intended for research use in studies of lipid metabolism and energy homeostasis.
- Inhibitor of carnitine palmitoyl transferase 1 (CPT1).
- Modulates fatty acid oxidation in cellular and biochemical assays.
- Provided as the lithium salt to aid solubility in aqueous systems.
- Useful for studies of mitochondrial metabolism and lipid regulation.
- Accompanied by datasheet, certificate of analysis, and safety data sheet.
![Medchemexpress LLC Spiro[2H-1-benzothiopyran-3(4H),1'-cyclopropan]-4-one, 2'-(4-methoxyphenyl)-, (1'R,2'R)-rel- | 1799392-31-6 | 99.8% | 296.38 g/mol | C18H16O2S | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000222792.png-250.jpg)
Medchemexpress LLC Spiro[2H-1-benzothiopyran-3(4H),1'-cyclopropan]-4-one, 2'-(4-methoxyphenyl)-, (1'R,2'R)-rel- | 1799392-31-6 | 99.8% | 296.38 g/mol | C18H16O2S | 5 MG
CYT296 is a small-molecule chromatin de-condensation compound for research use. It promotes an open chromatin state and can improve induction of induced pluripotent stem cells (iPSCs) when used with defined transcription factors.
- Promotes chromatin de-condensation and open chromatin state.
- Enhances efficiency of iPSC induction when combined with defined factors.
- Provided as a high-purity research chemical (99.8%).
- Available in small vial pack sizes suitable for laboratory experiments.
- Stable under recommended storage conditions for long-term use.
Medchemexpress LLC Nx-1607 | 2573775-59-2 | 99.9% | 537.62 | C30H34F3N5O | 5 MG
NX-1607 is a first-in-class, orally bioavailable small-molecule inhibitor of the E3 ubiquitin ligase Cbl-b. It exhibits sub-nanomolar potency (IC50 < 1 nM) and is used in preclinical and clinical immuno-oncology research to enhance T-cell activation, reduce exhaustion, and increase antigen recall and cytokine production. Supplied for laboratory research use only.
- Potent sub-nanomolar inhibitory activity against Cbl-b.
- Enhances T-cell activation and antigen recall.
- Reduces T-cell exhaustion and increases cytokine production.
- Orally bioavailable small molecule suitable for in vivo studies.
- High purity solid with white to off-white appearance.
- Stable when stored sealed; follow recommended storage conditions.
- Supplied in small-scale packaging for research applications.
Medchemexpress LLC RBP4 inhibitor 1 | 1198180-03-8 | 99.7% | 357.25 | C14H13F6NO3 | 5 MG
RBP4 inhibitor 1 is a potent, orally active retinol-binding protein 4 (RBP4) inhibitor reported to reduce blood RBP4 levels in vivo. It exhibits low-nanomolar activity against human RBP4 and is supplied as a high-purity research compound.
- Potent RBP4 inhibition: IC50 28 nM (human), 110 nM (mouse).
- High purity: 99.74%.
- Appearance: white to off-white solid.
- Molecular weight: 357.25 g/mol.
- Chemical formula: C14H13F6NO3.
- SMILES string provided for structural reference.
- Storage: powder at -20°C (stable for 3 years); in solvent -80°C for 6 months, -20°C for 1 month.
- Available in small research pack sizes and DMSO solutions for screening.
Medchemexpress LLC Biotin-PEG8-NHS ester | 2143968-03-8 | 99.9% | 764.88 | C33H56N4O14S | 5 MG
Biotin-PEG8-NHS ester is a biotinylation reagent composed of a biotin group linked via an 8-unit polyethylene glycol spacer to an N-hydroxysuccinimide (NHS) ester. The NHS ester reacts selectively with primary amines to form stable amide bonds, making this compound suitable for conjugation to peptides, proteins, and other amine-containing molecules for labeling, affinity capture, and linker applications in degraders research.
- High purity (99.9%).
- PEG8 spacer improves solubility and reduces steric hindrance.
- Reactive NHS ester enables efficient amine coupling.
- Suitable for protein labeling and affinity purification.
- Available in small research-scale pack sizes for convenience.
Medchemexpress LLC Uridine, 5-ethynyl- | 69075-42-9 | MFCD00876719 | 99.2% | 268.22 | C11H12N2O6 | 5 MG
5-Ethynyluridine is a cell-permeable uridine analog used to label newly synthesized RNA in cell and in vivo models. It contains an alkyne functional group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAC), allowing click-chemistry conjugation for isolation, sequencing, and visualization of nascent RNA.
- Cell-permeable uridine analog for nascent RNA labeling.
- Enables click-chemistry conjugation via alkyne (CuAAC).
- Suitable for RNA isolation, sequencing, and imaging workflows.
- Available as solid or ready-to-use DMSO solution formats.
- High purity suitable for molecular biology applications.
- Applicable in neuronal and in vivo transcription studies.
Medchemexpress LLC Picaridin 500mg | 119515-38-7 | 500 MG
Picaridin (Icaridin) is a research-grade insect repellent and analytical reference compound used in olfactory, repellency, and antimicrobial studies. It is supplied in solid and solution forms for laboratory use and intended for research and analytical applications only (not for human use).
- CAS number 119515-38-7.
- Chemical formula C12H23NO3.
- Molecular weight 229.32 g/mol.
- Purity reported around 99% (see lot-specific COA for exact value).
- Available in 500 mg and larger gram-scale quantities, and as prepared solutions (for example, 10 mM in DMSO).
- Suitable as an analytical standard and for repellency and olfactory testing.
Medchemexpress LLC Camptothecin-20S-O-p 5mg | 194414-69-2 | 404.42 g/mol | C23H20N2O5 | 5 MG
Camptothecin-20(S)-O-propionate (CZ48) is the C20-propionate ester prodrug of camptothecin. It is described as a potent anticancer agent that acts by stabilizing topoisomerase I-DNA covalent complexes, impairing DNA religation and leading to cell death. Supplied for laboratory research in solid and solution forms for in vitro and in vivo studies.
- Prodrug of camptothecin with the C20 propionate modification.
- Topoisomerase I inhibitor mechanism of action.
- High reported purity suitable for research applications.
- Available as small solid quantities and as a DMSO solution for dosing or assay preparation.
- Intended for research use only; not for human therapeutic use.
Medchemexpress LLC Octyl-a-ketoglutarat 1mg | 876150-14-0 | 1 MG
Octyl-α-ketoglutarate is a cell-permeable ester derivative of α-ketoglutarate used in biochemical and cell biology research to increase intracellular α-ketoglutarate and modulate α-ketoglutarate-dependent enzymes such as prolyl hydroxylases. Molecular formula C13H22O5; molecular weight 258.31 g/mol. Supplied as a solid powder; follow the supplier datasheet for storage and handling.
- Cell-permeable α-ketoglutarate ester.
- Increases intracellular α-ketoglutarate levels.
- Used to study HIF regulation and prolyl hydroxylase activity.
- Supplied as a solid; follow the datasheet for storage and handling.
Medchemexpress LLC Sotorasib racemate | 5MG
Sotorasib racemate (Compound A) is an orally active racemate of Sotorasib (HY-114277) a covalent inhibitor of KRAS G12C mutant which induces adaptive feedback activation of MAPK pathway Sotorasib racemate also exerts inhibitor activity against KRAS G12C induced cancer and can be applied to cancer research[1]