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Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1 – 15 of 2,748 results
1

(R)-2-Hydroxyglutaric acid disodium salt, Tocris Bioscience™
GREENER_CHOICE

KDM4A inhibitor; also NF-κB activator

2

Tocris Bioscience™ Filipin III
GREENER_CHOICE

Polyene antibiotic; inhibits formation of pathological isoform of prion protein

3

Tocris Bioscience™ A 83-01
GREENER_CHOICE

A 83-01 synthesized to Ancillary Material Grade

4

Tocris Bioscience™ Yoda 1
GREENER_CHOICE

Piezo1 channel activator

Target Other Calcium Channel Activators
CAS 448947-81-7
Purity >99%
Chemical Name or Material 2-[5-[[(2,6-Dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]pyrazine
Recommended Storage Store at 4°C
Molecular Formula C13H8Cl2N4S2
Formula Weight 355.27
5

Tocris Bioscience™ NTRC 824
GREENER_CHOICE

Potent and selective non-peptide NTS2 antagonist

Target Neurotensin Receptor Antagonists
CAS 1623002-61-8
Purity >98%
Chemical Name or Material N-[2-[5-[[(4-Methylphenyl)sulfonyl]amino]-3-(2,2,2-trifluoroacetyl)-1H-indol-1-yl]acetyl]-L-leucine
Recommended Storage Store at -20°C
Molecular Formula C25H26F3N3O6S
Formula Weight 553.55
6

Tocris Bioscience™ BIIE 0246 hydrochloride
GREENER_CHOICE

Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo

Target NPY Receptor Antagonists
CAS 2624332-04-1
Purity 0.98
Chemical Name or Material N-[(1 S)-4-[(Aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5 H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]-cyclopentaneacetamide hydrochloride
Recommended Storage Store at -20°C
Molecular Formula C49H57N11O6.HCl
7

Tocris Bioscience™ Blasticidin S HCl
GREENER_CHOICE

Antibiotic; selection reagent for bis, bsr and BSD transformed cells

8

Tocris Bioscience™ N-Acetylcysteine amide
GREENER_CHOICE

Glutathione (GSH) precursor; neuroprotective

Target Additional Antioxidant Compounds
CAS 38520-57-9
Chemical Name or Material (2R)-2-(Acetylamino)-3-mercaptopropanamide
Recommended Storage Store at -20°C
Molecular Formula C5H10N2O2S
Formula Weight 162.21
9

Tocris Bioscience™ Hydroxychloroquine sulfate
GSA_VA GREENER_CHOICE

Autophagy inhibitor; also TLR9 inhibitor

Target Autophagy-related Compounds
CAS 747-36-4
Purity >99%
Chemical Name or Material 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate
Recommended Storage Store at 4°C
Molecular Formula C18H28ClN3O5S
Formula Weight 433.95
10

Tocris Bioscience™ Polyamine Supplement x1000 (lyophilized)
GREENER_CHOICE

Media supplement to boost cell growth; used as component of CEPT cocktail to enhance stem cell viability

11

Tocris Bioscience™ Leukotriene B4
GREENER_CHOICE

CAS: 71160-24-2 Molecular Formula: C20H32O4

CAS 71160-24-2
Molecular Formula C20H32O4
12

Tocris Bioscience™ CI 988
GREENER_CHOICE

CAS: 130332-27-3 Molecular Formula: C35H42N4O6

CAS 130332-27-3
Molecular Formula C35H42N4O6
13

Tocris Bioscience™ Paroxetine maleate
GREENER_CHOICE

Highly potent and selective 5-HT uptake inhibitor

Inhibitors Paroxetine maleate
Product Type Paroxetine maleate
Molecular Weight (g/mol) 445.44
Purity >99%
14

Tocris Bioscience™ BIX 01294
GREENER_CHOICE

CAS: 1392399-03-9 Molecular Formula: C28H41Cl3N6O2

CAS 1392399-03-9
Molecular Formula C28H41Cl3N6O2
15

Tocris Bioscience™ SSR 180711 hydrochloride
GREENER_CHOICE

Partial agonist at α7 nAChR

Target Nicotinic (a7) Receptor Agonists
CAS 446031-79-4
Purity >98%
Chemical Name or Material 4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate hydrochloride
Recommended Storage Store at -20°C
Molecular Formula C14H17BrN2O2.HCl
Formula Weight 361.66