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Reagents containing reactive end groups that respond to the presence of specific functional groups by forming bonds between polymer chains. Ideal for various applications including conjugation reactions, biomolecule labeling, and molecular purification.
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(2-Pyridyldithio)-PEG4-propargyl is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting an E3 ubiquitin ligase ligand with a target protein ligand.
For research use only
PROTAC linker
Suitable for click chemistry applications involving alkynes
High purity of 98.5%
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BS3 Crosslinker is a water-soluble, non-cleavable, amine-reactive homobifunctional crosslinker (sulfo-NHS ester) designed for bioconjugation and protein crosslinking in aqueous systems. It selectively reacts with primary amines to form stable amide bonds and is commonly used for protein structural studies, surface crosslinking, and as a linker in antibody-drug conjugate research.
Water-soluble sulfo-NHS ester for use in aqueous buffers.
Reacts with primary amines to form stable amide bonds.
Non-cleavable linker for stable, long-lived conjugates.
Membrane-impermeable, suitable for surface and extracellular crosslinking.
Useful for bioconjugation, protein structural analysis, and linker development.
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Also available in 1 mL, 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. BS3 Crosslinker disodium, a non-cleavable ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs). Purity 97.94%
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BS3 Crosslinker disodium is a water-soluble, non-cleavable, homobifunctional amine-reactive crosslinker used to form stable amide bonds between primary amines. It is commonly used for antibody-drug conjugate synthesis, protein crosslinking, and bioconjugation workflows. CAS 127634-19-9; molecular weight 572.43; typical purity 98%.
Water-soluble homobifunctional crosslinker for amine-to-amine coupling.
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A homobifunctional crosslinking agent that contains amine-reactive NHS ester groups at EAch end; can be combined with formaldehyde fixation to improve the detection of specific protein-DNA complexes
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A selective κ1-opioid receptor partial agonist (Ki = 32.6); inhibits forskolin-stimulated cAMP production (EC50 = 4.7 nM); antinociceptive effects in mice at 13 UG, i.c.v.
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A synthetic glucocorticoid; inhibits dermatitis induced by ultraviolet light in guinea pigs (ED50 = 1.45 UG/animal) and by oxazolone in mice (ED50 = 0.8 UG/animal); has anti-inflammatory effects on croton oil-induced EAr edema in rats (ED50s = 10 UG/ml and 0.5 UG/ear) and mice (ED50s = 1.2 and <0.32 UG/ear after 6 and 24 hours of treatment, respectively)
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Formula: C23H18N2O5, Purity: 97%, MW: 402.4, DBCO-NHS Ester is an amine-reactive compound and can be used to modify an amine-containing molecule in organic solvents (limited solubility in aqueous media). It reacts with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. The low mass weight will add minimal spacer to modified molecules.
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