Protein Modification Reagents
eMolecules 308805-39-2 | DSG-PEG, MW 2,000 | Broadpharm727.165 | C44H86O7 | 98.000 | CCCCCCCCCCCCCCCCCC(=O)OCC(COCCOCCOC)OC(=O)CCCCCCCCCCCCCCCCC | 250mg | 761705486
DSG-PEG, MW 2,000 | Broadpharm | 308805-39-2727.165 | C44H86O7 | 98.000 | CCCCCCCCCCCCCCCCCC(=O)OCC(COCCOCCOC)OC(=O)CCCCCCCCCCCCCCCCC | 250mg | 761705486
Medchemexpress LLC endo-BCN-PEG2-alcohol | 1807501-85-4 | 98.0% | 325.40 | 25 MG
endo-BCN-PEG2-alcohol is a PEG-based PROTAC linker employed in the synthesis of PROTACs. This compound functions as a click chemistry reagent, featuring a BCN group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Functions as a click chemistry reagent.
- Contains a BCN group for strain-promoted alkyne-azide cycloaddition (SPAAC).
![eMolecules N-(Azido-PEG1)-N-bis(PEG2-Methyltetrazine-propylamine) | Broadpharm |905.031 | C42H60N14O9 | 95.000 | Cc1nnc(nn1)-c1ccc(OCCCNC(=O)CCOCCOCCN(CCOCCOCCC(=O)NCCCOc2ccc(cc2)-c2nnc(C)nn2)CCOCCN=[N+]=[N-])cc1 | 10mg | 724438921](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502474400.JPG-250.jpg)
eMolecules N-(Azido-PEG1)-N-bis(PEG2-Methyltetrazine-propylamine) | Broadpharm |905.031 | C42H60N14O9 | 95.000 | Cc1nnc(nn1)-c1ccc(OCCCNC(=O)CCOCCOCCN(CCOCCOCCC(=O)NCCCOc2ccc(cc2)-c2nnc(C)nn2)CCOCCN=[N+]=[N-])cc1 | 10mg | 724438921
N-(Azido-PEG1)-N-bis(PEG2-Methyltetrazine-propylamine) | Broadpharm |905.031 | C42H60N14O9 | 95.000 | Cc1nnc(nn1)-c1ccc(OCCCNC(=O)CCOCCOCCN(CCOCCOCCC(=O)NCCCOc2ccc(cc2)-c2nnc(C)nn2)CCOCCN=[N+]=[N-])cc1 | 10mg | 724438921
![Alkali Scientific PEG 8000 [Polyethylene Glycol 8000], 15 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661609.jpg-250.jpg)
Alkali Scientific PEG 8000 [Polyethylene Glycol 8000], 15 Kg
Polyethylene Glycol 8000 (PEG 8000) is a polymer used in laboratory applications to simulate molecular crowding environments. Its high molecular weight makes it useful for a variety of applications, such as enzyme stabilization, protein precipitation, and improving the solubility of macromolecules. PEG 8000 is also utilized in DNA extraction procedures and the preparation of high-concentration protein solutions. This reagent plays a key role in mimicking cellular environments, aiding in protein-protein interactions, and enhancing the efficiency of biochemical reactions. Available in a 15 kg package, it provides ample material for large-scale or extended research projects requiring high molecular weight PEG.
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG5-CH2COOH | 100 g | CAS 635287-26-2 | InChIKey LNIFRTLAPAPKAG-UHFFFAOYSA-N
Fmoc-NH-PEG5-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 635287-26-2
- MDL: No data
- InChIKey: LNIFRTLAPAPKAG-UHFFFAOYSA-N
- Molecular Weight: 517.575
- Molecular Formula: C27H35NO9
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azahenicosan-21-oic acid
- SMILES: O=C(COCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Medchemexpress LLC Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane | 1421933-29-0 | 97.0% | C36H66N4O14 | 100 MG
Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group. This enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Alkyne-containing molecules and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds containing DBCO or BCN groups. PROTACs leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Features an Azide group
- Enables CuAAc and SPAAC reactions
- Supports PROTACs in degrading target proteins
Medchemexpress LLC Biotin-PEG5-NHS ester | Not provided | Not provided | 98.0% | 632.72 g/mol | C27H44N4O11S | 10 MG
Biotin-PEG5-NHS ester is a biotinylation reagent composed of a biotin moiety connected through a five-unit polyethylene glycol spacer to an N-hydroxysuccinimide (NHS) ester. The NHS ester reacts with primary amines to form stable amide bonds, enabling efficient and selective labeling of proteins, peptides, and surfaces for downstream capture or detection workflows.
- Enables covalent coupling to primary amines via NHS ester chemistry.
- Five-unit PEG spacer reduces steric hindrance and improves solubility.
- Biotin tag enables high-affinity binding to streptavidin or neutravidin.
- High purity (98.0%) suitable for labeling and analytical workflows.
- Soluble in DMSO for convenient stock solution preparation.
- Stable when stored dry at -20°C; store solutions frozen for longer-term stability.
Medchemexpress LLC Amino-PEG5-CH2COOH | 141282-35-1 | ≥97.0% | 100 MG
Amino-PEG5-CH2COOH is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It leverages the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- Peg-based protac linker
- Utilized in the synthesis of protacs
- Consists of two distinct ligands connected by a linker
- Targets E3 ubiquitin ligase and protein of interest
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC m-PEG4-CH2COOH | 16024-66-1 | 99.9% | 5 G
m-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Molecular weight: 266.29
- Formula: C11H22O7
- Appearance: Liquid (density: 1.125 g/cm³)
- Color: Colorless to light yellow
- Shipping at room temperature (in continental US)
- Storage (pure form): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- In vitro solubility: DMSO: 100 mg/mL
- In vivo solubility: ≥ 2.5 mg/mL in various protocols
Medchemexpress LLC Azido-PEG4-azide | 182760-73-2 | ≥97.0% | 288.30 | 500 MG
Azido-PEG4-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent containing an azide group. This allows it to undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Medchemexpress LLC DSPE-PEG-Folate | 1236288-25-7 | MFCD07107414 | 95.7% | 5000 | 5 MG
DSPE-PEG-Folate (MW 5000) is a PEGylated phospholipid in which DSPE is linked to a polyethylene glycol chain terminated with folic acid. It is designed to incorporate into liposomes or nanoparticle surfaces to present folate ligands for receptor-mediated targeting and uptake, and is used in targeted drug delivery, imaging, and nanoparticle functionalization in research settings.
- Facilitates folate-receptor mediated targeting.
- Integrates into lipid bilayers and can form micelles.
- Average molecular weight of 5000 for extended circulation properties.
- High purity (≈95.7%) suitable for research applications.
- Stable as a powder when stored at -20°C for long-term storage.
Medchemexpress LLC 3,6,9,15,18,21-Hexaoxa-12-azatricosane-1,23-diol | 63721-14-2 | 98.0% | C16H35NO8 | 500 MG
NH-bis-PEG4 is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These compounds employ the intracellular ubiquitin-proteasome system to specifically degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Leverages the ubiquitin-proteasome system
- Specifically degrades target proteins
Medchemexpress LLC TAMRA-PEG4-acid | 1909223-02-4 | 95.3% | C36H43N3O10 | 50 MG
TAMRA-PEG4-acid is a dye derivative of TAMRA containing 3 PEG units. This fluorescent dye is intended for research use only, suitable for laboratory chemicals and the manufacture of substances.
- Target: Fluorescent dye
- Molecular weight: 677.80
- Solubility in DMSO: 100 mg/mL (147.54 mM)
- Appearance: Liquid, brown to reddish brown
Medchemexpress LLC Biotin-PEG-azide | 956494-20-5 | 98.7% | 2000.00 | 100 MG
Biotin-PEG-azide (MW 2000) is a biotinylated polyethylene glycol derivative with a terminal azide functional group. Supplied as a powder with an average molecular weight of 2000, it is designed for use in bioconjugation workflows such as copper-catalyzed azide-alkyne cycloaddition and for affinity labeling or capture of biomolecules. Manufacturer datasheets provide purity, storage, and handling details.
Medchemexpress LLC Mal-amido-PEG6-acid | 1334177-79-5 | 99.3% | 50 MG
Mal-amido-PEG6-acid is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These molecules are designed to exploit the intracellular ubiquitin-proteasome system, selectively degrading target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein.
- PEG-based PROTAC linker
- Used for PROTAC synthesis
- Enables targeted protein degradation
- Facilitates connection of E3 ubiquitin ligase and target protein ligands