Protein Modification Reagents
Medchemexpress LLC Azido-PEG4-Amido-Tris | 1398044-55-7 | 96.4% | C15H30N4O8 | 25 MG
Azido-PEG4-Amido-Tris is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs themselves consist of two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for a target protein, and they degrade target proteins by utilizing the intracellular ubiquitin-proteasome system.
- Functions as a PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Acts as a click chemistry reagent
- Contains an Azide group for CuAAc reactions
- Participates in SPAAC reactions with DBCO or BCN groups
Medchemexpress LLC DSPE-PEG carboxylic acid (sodium) | 1403744-37-5 | 98.0% | (C2H4O)nC45H86NO12P.Na | 25 MG
DSPE-PEG Carboxylic acid (sodium), MW 2000 is a PEG-lipid that can be used in the preparation of drug delivery nanoparticles. It is capable of extending the blood circulation time and stability of liposomes, while also improving the targeting ability and cellular uptake efficiency of nanoparticles.
- Used in the preparation of drug delivery nanoparticles
- Prolongs the blood circulation time and stability of liposomes
- Enhances the targeting ability of nanoparticles
- Improves cellular uptake efficiency of nanoparticles
Medchemexpress LLC DBCO-PEG4-Desthiobiotin | 2032788-37-5 | 96.4% | C39H53N5O8 | 25 MG
DBCO-PEG4-Desthiobiotin is a PEG-based PROTAC linker used in the synthesis of PROTACs. It also functions as a click chemistry reagent, featuring a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups. This product is intended for research use only.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
- Reacts with azide groups
- For research use only
Medchemexpress LLC 5,8,11,14-tetraoxa-2-azahexadecanedioic acid, 1-(1,1-dimethylethyl) ester | 876345-13-0 | MFCD30528568 | 97.0% | 351.39 | C15H29NO8 | 500 MG
Boc-NH-PEG4-CH2COOH is a Boc-protected PEG4 linker with a terminal carboxylic acid, intended for use as a cleavable linker in antibody-drug conjugate (ADC) synthesis and as a PEG-based PROTAC linker in medicinal chemistry and bioconjugation research.
- Boc-protected amino group for orthogonal protection
- Four-unit polyethylene glycol spacer for improved solubility and flexibility
- Terminal carboxylic acid for amide coupling or conjugation
- High purity suitable for research applications
- Stable under recommended storage conditions
eMolecules N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester) | 2093153-97-8 | MFCD30723262 | 500mg
Broadpharm | N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester) | 500mg | 340376923 | BP-23525 | 98.000 | 2093153-97-8 | MFCD30723262 | 845.078 | C40H80N2O16
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