Protein Modification Reagents
![eMolecules 2566404-74-6 | 4-Azide-TFP-Amide-PEG4-acid | Broadpharm482.389 | C18H22F4N4O7 | 0.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)c1c(F)c(F)c(N=[N+]=[N-])c(F)c1F | 50mg | 563055131](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502476191.JPG-250.jpg)
eMolecules 2566404-74-6 | 4-Azide-TFP-Amide-PEG4-acid | Broadpharm482.389 | C18H22F4N4O7 | 0.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)c1c(F)c(F)c(N=[N+]=[N-])c(F)c1F | 50mg | 563055131
4-Azide-TFP-Amide-PEG4-acid | Broadpharm | 2566404-74-6482.389 | C18H22F4N4O7 | 0.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)c1c(F)c(F)c(N=[N+]=[N-])c(F)c1F | 50mg | 563055131
STA Pharmaceutical Fmoc-NH-PEG6-CH2COOH | 25 g | CAS 437655-96-4 | MDL MFCD26142983
Fmoc-NH-PEG6-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 437655-96-4
- MDL: MFCD26142983
- InChIKey: HANLHKUCDRJGKX-UHFFFAOYSA-N
- Molecular Weight: 561.628
- Molecular Formula: C29H39NO10
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azatetracosan-24-oic acid
- SMILES: O=C(NCCOCCOCCOCCOCCOCCOCC(O)=O)OCC1C2=C(C3=C1C=CC=C3)C=CC=C2
Medchemexpress LLC Bromoacetamido-PEG4-C2-Boc | 1807521-00-1 | 250 MG
Bromoacetamido-PEG4-C2-Boc is a laboratory chemical (CAS No. 1807521-00-1) primarily utilized in the manufacture of substances. This compound exhibits good stability when stored under recommended conditions and typically appears as a liquid. It possesses a molecular formula of C17H32BrNO7 and a molecular weight of 442.34.
- Suitable for laboratory research and substance manufacturing
- Stable under recommended storage conditions
- Appears as a liquid
- Molecular formula: C17H32BrNO7
- Molecular weight: 442.34
- Storage (pure form): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- Shipping at room temperature if less than 2 weeks
Medchemexpress LLC Dmg-peg-nhs | 95.0% | 2000 (Average) | 25 MG
This compound is composed of Myristic acid and PEG linked by an amide bond, with NHS as an active ester group attached to the end of the PEG chain. It is suitable for various applications including protein/biomolecule modification, gene delivery, and biosensor applications.
- Used for protein/biomolecule modification
- Suitable for gene delivery
- Applicable in biosensor applications
- For research use only
Cayman Chemical BIotIn-PEG3-azIde 50mg
A PEGylated version of biotin-azide that is more hydrophilic; can be used to label terminal alkynes via copper-catalyzed click reactions or copper-free click reactions with cyclooctynes; used to covalently tag proteins in combination with other tags
Medchemexpress LLC Aminooxy-PEG2-azide | 1043426-13-6 | ≥96.0% | 190.20 | 250 MG
Aminooxy-PEG2-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs and as a non-cleavable 2-unit PEG ADC linker for antibody-drug conjugates. It functions as a click chemistry reagent with an Azide group.
- Enables copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing alkyne groups.
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Utilized in the synthesis of PROTACs.
- Employed in the synthesis of antibody-drug conjugates (ADCs).
![eMolecules 2112731-96-9 | N-(Azido-PEG3)-N-Boc-PEG4-NHS ester | Broadpharm | MFCD30723220 | 663.722 | C28H49N5O13 | 98.000 | CC(C)(C)OC(=O)N(CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)CCOCCOCCOCCN=[N+]=[N-] | 500mg | 343283657](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203401.JPG-250.jpg)
eMolecules 2112731-96-9 | N-(Azido-PEG3)-N-Boc-PEG4-NHS ester | Broadpharm | MFCD30723220 | 663.722 | C28H49N5O13 | 98.000 | CC(C)(C)OC(=O)N(CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)CCOCCOCCOCCN=[N+]=[N-] | 500mg | 343283657
N-(Azido-PEG3)-N-Boc-PEG4-NHS ester | Broadpharm | 2112731-96-9 | MFCD30723220 | 663.722 | C28H49N5O13 | 98.000 | CC(C)(C)OC(=O)N(CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)CCOCCOCCOCCN=[N+]=[N-] | 500mg | 343283657
LAB ALLEY Lab Alley Polyethylene Glycol (PEG) 400 Food Grade (FCC) Halal
Polyethylene Glycol is synthesized by ring-opening polymerization of ethylene oxide. This synthesis process gives PEG a range of molecular weights and distributions from 300 grams per mole to 10000000 grams per mole. PEG 400 has a molecular weight of 400 and is a clear colorless viscous liquid. Polyethylene Glycol is colorless inert odorless and non-volatile. PEG is biocompatible (it will not damage tissues or cells) hydrophilic dissolves readily in water without changing the color odor or taste and is nontoxic. Due to the high purity of Polyethylene Glycol 400 it is certified by the United States Pharmacopeia (USP) grade and the Food Chemicals Codex (FCC) grade.
Medchemexpress LLC Ald-ph-amido-peg4-c2-acid | 1309460-27-2 | 99.1% | 397.42 | C19H27NO8 | 250 MG
Ald-Ph-amido-PEG4-C2-acid is a noncleavable polyethylene glycol (PEG4) linker intended for use in antibody-drug conjugate (ADC) research. It provides a stable, non-cleavable connection between an antibody and a payload, and is supplied at high purity to support reproducible bioconjugation.
- Noncleavable PEG4 linker suitable for ADC development.
- Terminal carboxylic acid enables amide coupling to payloads.
- Benzaldehyde moiety enables selective conjugation to hydrazide or aminooxy groups.
- High purity supports reproducible conjugation results.
- Molecular weight 397.42 g/mol and formula C19H27NO8.
Cayman Chemical CLS-MPEG 2000 5mg
A PEGylated form of cholesterol; has been used in the synthesis of liposomes for targeted drug delivery
Medchemexpress LLC NHPI-PEG4-C2-NHS ester | 1415328-95-8 | MFCD28155511 | 98.9% | 508.48 g/mol | C23H28N2O11 | 100 MG
NHPI-PEG4-C2-NHS ester is an activated N-hydroxyphthalimide (NHPI) N-hydroxysuccinimide (NHS) ester bearing a PEG4-C2 spacer, supplied as a research-grade ADC linker reagent for use in the synthesis of antibody-drug conjugates. The compound has CAS 1415328-95-8, molecular weight 508.48 g/mol, chemical formula C23H28N2O11, and a reported purity of 98.9%.
- Activated NHS ester for conjugation to amines.
- PEG4-C2 spacer provides hydrophilicity and distance between payload and antibody.
- High reported purity suitable for research applications.
- Available in multiple package sizes, including 100 mg.
- Supplied with product data sheet and safety data sheet for handling information.
Medchemexpress LLC m-PEG4-CH2COOH | 16024-66-1 | 99.9% | 250 MG
m-PEG4-CH2COOH is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs utilize two distinct ligands, connected by a linker, where one ligand binds to an E3 ubiquitin ligase and the other targets a specific protein. This mechanism exploits the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC DBCO-PEG4-Biotin | 1255942-07-4 | >99.4% | 1 ML
DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative that includes a biotin group and four PEG units. It functions as a versatile biotinylation reagent, enabling the introduction of a biotin moiety to azide-labeled biomolecules through copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reactions. The DBCO group within DBCO-PEG4-Biotin facilitates SPAAC with molecules containing azide groups.
- Versatile biotinylation reagent
- Introduces biotin moiety to azide-labeled biomolecules
- Utilizes copper-free strain-promoted alkyne-azide click chemistry (SPAAC)
- DBCO group facilitates SPAAC with azide groups
Medchemexpress LLC Biotin-PEG3-azide | 875770-34-6 | MFCD20134145 | ≥97.0% | 444.55 g/mol | C18H32N6O5S | 5 MG
Biotin-PEG3-azide is a PEGylated biotinylation reagent bearing a terminal azide group for copper-catalyzed click chemistry. It is employed as a linker in PROTAC synthesis and for affinity labeling and bioconjugation workflows requiring streptavidin capture.
- Provides a three-unit PEG spacer for increased solubility and reduced steric hindrance.
- Includes a terminal azide group compatible with click conjugation to alkynes.
- Delivers a biotin affinity tag for efficient capture by streptavidin.
- High purity suitable for research applications.
- Soluble in DMSO and water with sonication as needed.
- Stable as a powder when stored at low temperatures.
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(PEG2000) (ammonium salt) | 474922-26-4 | 99.96% | 2790.52 | (C2H4O)nC44H87N2O10P.NH3 | 5MG
DSPE-PEG(2000) Amine is an amine-terminated PEGylated phospholipid used to functionalize liposomes and lipid nanoparticles for surface conjugation and targeted delivery. The hydrophobic DSPE tail anchors the molecule in lipid bilayers, while the PEG2000 spacer provides steric stabilization and improved colloidal stability; the terminal primary amine enables covalent coupling to activated esters, dyes, linkers, or targeting ligands.
- Amine-terminated PEGylated phospholipid for surface functionalization.
- Hydrophobic tail anchors stably in lipid bilayers.
- Peg spacer provides steric stabilization and reduces aggregation.
- Terminal primary amine enables covalent coupling chemistries.
- Offered as an ammonium salt in powder and solution forms.
- High purity suitable for research use (supplier-stated ~99.96%).
- Store at -20°C; soluble in chloroform:methanol mixtures.