Protein Modification Reagents
eMolecules 2353410-14-5 | t-Boc-Aminooxy-PEG8-alcohol | Broadpharm485.571 | C21H43NO11 | 98.000 | CC(C)(C)OC(=O)NOCCOCCOCCOCCOCCOCCOCCOCCO | 500mg | 550804524
t-Boc-Aminooxy-PEG8-alcohol | Broadpharm | 2353410-14-5485.571 | C21H43NO11 | 98.000 | CC(C)(C)OC(=O)NOCCOCCOCCOCCOCCOCCOCCOCCO | 500mg | 550804524
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-PEG-thiol | >95.0% | 25 MG
DSPE-PEG-SH (average MW 1,000 Da) is a thiol-terminated PEGylated phospholipid combining a DSPE lipid anchor with a polyethylene glycol spacer that ends in a reactive sulfhydryl. Supplied as a solid, it is used to introduce surface-accessible thiol groups into liposomes, lipid nanoparticles, and other lipid assemblies for bioconjugation and targeted delivery applications.
- Provides a lipid anchor for stable incorporation into bilayers.
- Contains a terminal thiol (-SH) for conjugation to thiol-reactive reagents.
- Average molecular weight ~1,000 Da for the PEG spacer.
- Facilitates surface functionalization of nanoparticles and liposomes.
- Typically supplied as a powder with high purity (≥95%).
- Useful for preparing targeted delivery systems and bioconjugates.
Cayman Chemical Aceclofenac methyl ester 100mg
A potential impurity in commercial preparations of aceclofenac; has been used as a precursor in the synthesis of aceclofenac
Chemscene ChemScene | Biotin-PEG4-hydrazide | 100MG | CS-0114565 | 0.97 | 756525-97-0| MFCD09952658 | 505.63
ChemScene | Biotin-PEG4-hydrazide | 100MG | CS-0114565 | 0.97 | 756525-97-0| MFCD09952658 | 505.63
Chemscene ChemScene | Mal-PEG6-NHS ester | 250MG | CS-0104984 | 0.98 | 1599472-25-9| MFCD20926374 | 530.52
ChemScene | Mal-PEG6-NHS ester | 250MG | CS-0104984 | 0.98 | 1599472-25-9| MFCD20926374 | 530.52
Chemscene ChemScene | Biotin-PEG1-NH2 | 250MG | CS-0147801 | 0.97 | 811442-85-0| MFCD28397128 | 330.45
ChemScene | Biotin-PEG1-NH2 | 250MG | CS-0147801 | 0.97 | 811442-85-0| MFCD28397128 | 330.45
Medchemexpress LLC 4,7,10,13,16,19-Hexaoxa-22-azapentacosanoic acid, 25-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-2 3-oxo-, 2,5-dioxo-1-pyrrolidinyl ester | 1137109-21-7 | 98.8% | 601.60 | 250 MG
Mal-amido-PEG6-NHS ester is a PROTAC linker, based on PEG, that is utilized in the synthesis of PROTACs. PROTACs themselves are composed of two distinct ligands connected by a linker, where one ligand binds to an E3 ubiquitin ligase and the other to a target protein. These molecules function by leveraging the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins.
- Peg-based PROTAC linker.
- Used in the synthesis of PROTACs.
- PROTACs utilize the ubiquitin-proteasome system for selective protein degradation.
Medchemexpress LLC Dspe-peg-maleimide, MW 5000 | 99.8% | 100 MG
Dspe-peg-maleimide, MW 5000, is a linker lipid containing DSPE phospholipid and Maleimide. This compound is used in the synthesis of various liposomes and as a linker in immunoliposome synthesis for laboratory applications.
- Contains DSPE phospholipid and Maleimide.
- Utilized in liposome synthesis (HELDC, sterically stabilized, and immunoliposomes).
- Can be coupled with thiol-p5314-29 peptide for immunoliposome synthesis.
- Sterically stabilized liposomes can be coupled with thiolated monoclonal antibody OX26 (OX26-SH).
- HELDC liposomes with 3% DSPE-PEG-maleimide maintain particle size stability over two weeks (avg. 120 nm diameter).
- Molecular weight: 5000 (average).
- Appears as a white to off-white solid.
- For research use only.
Medchemexpress LLC NH2-PEG4-DOTA | 2090232-34-9 | 97.0% | 622.71 g/mol | C26H50N6O11 | 10mg
NH2-PEG4-DOTA is a bifunctional DOTA-type metal chelator NH2-PEG4-DOTA can be conjugated with Dextran for quantitative analysis in the presence of a highly luminescent complex NH2-PEG4-DOTA can also bind to radionuclides to prepare radionuclide drug conjugates (RDCs) RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy
Medchemexpress LLC Bis-PEG4-TFP ester | 1446282-42-3 | 98.0% | 590.41 | C24H22F8O8 | 100 MG
Bis-PEG4-TFP ester is a PEG-based bifunctional linker with two tetrafluorophenyl (TFP) ester reactive termini separated by a PEG4 spacer. It is intended for conjugation in the synthesis of proteolysis-targeting chimeras (PROTACs) and other bifunctional molecules.
- Provides two TFP ester reactive termini for efficient conjugation
- PEG4 spacer improves solubility and molecular flexibility
- High purity suitable for research synthesis (98.0%)
- Molecular weight 590.41 and CAS 1446282-42-3 for precise identification
- Available in multiple pack sizes, including 100 mg
- Store at -20°C, protect from light, under inert atmosphere
- Suitable for use in PROTAC assembly and linker optimization
eMolecules DBCO-PEG6-Maleimide | Broadpharm |762.857 | C40H50N4O11 | 0.000 | O=C(CCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 25mg | 686678577
DBCO-PEG6-Maleimide | Broadpharm |762.857 | C40H50N4O11 | 0.000 | O=C(CCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 25mg | 686678577
Medchemexpress LLC DM1-PEG4-DBCO | 1198.79 g·mol⁻¹ | C63H80ClN5O16 | 10 MG
DM1-PEG4-DBCO is an agent-linker conjugate that combines the potent microtubule inhibitor DM1 with a DBCO-PEG4-Ahx linker to enable antibody-drug conjugate (ADC) synthesis via strain-promoted alkyne-azide cycloaddition (SPAAC). It is supplied as a solid reagent for research use only.
- Agent-linker conjugate combining DM1 with a DBCO-PEG4-Ahx linker.
- Designed for antibody-drug conjugate synthesis and bioconjugation.
- Contains DBCO for strain-promoted alkyne-azide cycloaddition (SPAAC).
- Enables conjugation to azide-containing biomolecules.
- Supplied as a solid reagent; store protected from light at -20°C.
Medchemexpress LLC 2,5-pyrrolidinedione derivative (PEG1 NHS ester) | 173414-89-6 | 97.0% | 627.55 g/mol | C26H33N3O15 | 100 MG
m-C-tri(CH2-PEG1-NHS ester) is a non-cleavable, single-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker bearing an N-hydroxysuccinimide (NHS) ester for amine coupling. Supplied as a solid for research use, it provides a stable, non-cleavable spacer that improves solubility and facilitates conjugation.
- Non-cleavable single-unit PEG linker for stable spacing
- NHS ester functionality for efficient amine conjugation
- Improves payload solubility
- Supplied as a solid with ~97.0% purity (NMR)
- Available in multiple sample sizes for research (50 mg-1 g)
eMolecules 2100306-71-4 | Bromo-PEG3-CH2CO2tBu | Broadpharm | MFCD30723231 | 327.215 | C12H23BrO5 | 98.000 | CC(C)(C)OC(=O)COCCOCCOCCBr | 500mg | 343283690
Bromo-PEG3-CH2CO2tBu | Broadpharm | 2100306-71-4 | MFCD30723231 | 327.215 | C12H23BrO5 | 98.000 | CC(C)(C)OC(=O)COCCOCCOCCBr | 500mg | 343283690
(=O)OCCNC(=O)OCCOC)OC(=O)CCCCCCCCCCCCC | 5mg | 718091915](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502486701.JPG-250.jpg)
eMolecules 474922-82-2 | 14:0 PEG PE, MW 550 | Broadpharm737.953 | C37H72NO11P | 95.000 | CCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCNC(=O)OCCOC)OC(=O)CCCCCCCCCCCCC | 5mg | 718091915
14:0 PEG PE, MW 550 | Broadpharm | 474922-82-2737.953 | C37H72NO11P | 95.000 | CCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCNC(=O)OCCOC)OC(=O)CCCCCCCCCCCCC | 5mg | 718091915