Protein Modification Reagents
Medchemexpress LLC Aminooxy-PEG1-azide | 2100306-70-3 | MFCD30723212 | 98.0% | 146.15 g/mol | C4H10N4O2 | 5 MG
Aminooxy-PEG1-azide is a short bifunctional polyethylene glycol (PEG) linker bearing an aminooxy group and an azide group. It is designed for chemical biology and bioconjugation applications where orthogonal conjugation is required, enabling oxime ligation at one terminus and click chemistry at the other. Intended for research use only.
- Enables oxime ligation with aldehydes and ketones.
- Participates in copper-catalyzed and strain-promoted azide-alkyne cycloadditions.
- Provides a short PEG spacer to improve aqueous solubility and reduce steric hindrance.
- Suitable for linker construction in proteolysis targeting chimeric molecule (PROTAC) and bioconjugation workflows.
- Reported purity approximately 98%, compatible with research applications.
eMolecules Broadpharm / t-BuO2C-PEG4-SS-PEG4-CO2tBu / 250mg / 282987761 / BP-22787 / 98.000 / / MFCD28950761 / 674.900 / C30H58O12S2
Broadpharm / t-BuO2C-PEG4-SS-PEG4-CO2tBu / 250mg / 282987761 / BP-22787 / 98.000 / / MFCD28950761 / 674.900 / C30H58O12S2
Medchemexpress LLC DSPE-biotin | 133695-76-8 | MFCD34561787 | 97.5% | 974.36 | C51H96N3O10PS | 10 MG
DSPE-Biotin is a biotinylated phospholipid used to introduce biotin functionality into liposomes, lipid bilayers, and other lipid-based formulations for biochemical research and bioconjugation. It facilitates specific capture, labeling, and immobilization through high-affinity streptavidin/avidin interactions.
- Provides biotin functionality for liposomes and lipid bilayers.
- Enables high-affinity binding to streptavidin and avidin.
- Suitable for liposome formulation and surface immobilization applications.
- Soluble in DMSO; ultrasonic warming improves solubility.
- High purity for research use; handle and store protected from light.
- Stable when stored at -20°C for long-term storage.
eMolecules FMOC-NH-PEG12-CH2CH2COOH | 756526-01-9 | MFCD08064302 | 1g
AstaTech | FMOC-NH-PEG12-CH2CH2COOH | 1g | 516650164 | S10746 | 95.000 | 756526-01-9 | MFCD08064302 | 839.973 | C42H65NO16
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Medchemexpress LLC DSPE-PEG-SH | 1462982-18-8 | 99.4% | 2000 Da (average) | C44H86NO10PS | 50 MG
DSPE-PEG-SH is a thiol-terminated pegylated phospholipid (average MW 2000) designed for incorporation into lipid bilayers and lipid nanoparticle formulations. The terminal -SH group enables covalent surface functionalization and bioconjugation for targeted delivery or conjugate assembly.
- Thiol-terminated PEG2000 conjugated to distearoyl phosphoethanolamine.
- Amphipathic lipid integrates into lipid bilayers and nanoparticles.
- Reactive thiol group for covalent conjugation with maleimide.
- Average molecular weight 2000 Da.
- High purity (≈99.4%).
- White to off-white solid with defined solubility in water and DMSO when warmed.
- Powder stable at -20°C; in solution store at -80°C for long-term stability.
Medchemexpress LLC Endo-BCN-PEG2-NH2 | 1263166-93-3 | 97.0% | 324.42 | C17H28N2O4 | 5 MG
endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that contains a bicyclo[6.1.0]non-4-yne (BCN) moiety, enabling strain-promoted alkyne-azide cycloaddition (SPAAC) for copper-free click conjugation. It is intended for use in targeted protein degradation research and bioconjugation workflows.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) for copper-free click conjugation.
- Contains a PEG2 spacer to improve solubility and provide flexibility.
- Primary amine functional group allows straightforward coupling chemistry.
- Suitable for small-scale synthesis and bioconjugation applications.
- Available in low-milligram quantities for research use.
Cayman Chemical CLS-MPEG 2000 10mg
A PEGylated form of cholesterol; has been used in the synthesis of liposomes for targeted drug delivery
Medchemexpress LLC CPTH2-alkyne | 1613116-16-7 | 99.0% | 5 MG
CPTH2-alkyne is an alkyne-tagged analog of CPTH2 that inhibits N-acetyltransferase 10 (NAT10). It accumulates in nucleoli, localizes to the nuclear periphery and cytoplasm, and is supplied as a high-purity research compound for studies of nuclear architecture and laminopathy.
- Alkyne-tagged analog suitable for bioorthogonal click chemistry.
- Inhibits N-acetyltransferase 10 (NAT10) for epigenetic studies.
- Accumulates in nucleoli and localizes to nuclear periphery and cytoplasm.
- High purity (99.0%) for research applications.
- Stable as a powder at -20°C for up to 3 years.
Medchemexpress LLC Dspe-peg-fitc | 95.0% | 600 Da (average) | 10 MG
Fluorescein-labeled PEGylated phospholipid supplied as a powder with an average molecular weight of approximately 600 Da. This reagent-grade fluorescent lipid conjugate is designed for incorporation into liposomes and lipid nanoparticles to enable fluorescent labeling, tracking, and imaging in laboratory research. It is supplied for research use only and can form micelles in aqueous solution.
- Fluorescent pegylated phospholipid for liposome and nanoparticle labeling.
- Average molecular weight 600 Da (average).
- Reagent grade powder suitable for research use.
- Forms micelles in aqueous solution.
- Purity 95.0% per certificate of analysis.
- Store protected from light at 4°C; in solvent store at -80°C for up to 6 months.
Medchemexpress LLC Bis-sulfone-PEG3-azide | 1802908-01-5 | MFCD29052187 | 97.8% | 700.82 g/mol | C33H40N4O9S2 | 5 MG
Bis-sulfone-PEG3-azide is a PEG-based, cleavable linker bearing an azide functional group used for bioconjugation and ADC/PROTAC linker synthesis. It enables click chemistry conjugation (CuAAC and SPAAC) between azide and alkyne functional groups, and is supplied as a small-molecule reagent for research use.
- Cleavable ADC and PROTAC linker for bioconjugation.
- Contains an azide group for CuAAC and strain-promoted cycloaddition (SPAAC) reactions.
- Molecular weight approximately 700.82 g/mol; molecular formula C33H40N4O9S2.
- CAS number 1802908-01-5 for unambiguous chemical identification.
- Available in a 5 mg pack; larger sizes available by quote.
- Storage: dry, -20°C (stable ~3 years); in solvent, -80°C (6 months) or -20°C (1 month).
eMolecules Ambeed / Fmoc-21-amino-4710131619-hexaoxaheneicosanoic acid / 100mg / 525195261 / A356631 / / 882847-34-9 / MFCD06656474 / 575.655 / C30H41NO10
Ambeed / Fmoc-21-amino-4710131619-hexaoxaheneicosanoic acid / 100mg / 525195261 / A356631 / / 882847-34-9 / MFCD06656474 / 575.655 / C30H41NO10
Medchemexpress LLC Dopamine-PEG-N3 MW 25mg
Dopamine-PEG-N3 (MW 2000) (Dopamine-PEG-Azide (MW 2000)) is a compound composed of dopamine PEG segments and an azide group (-N3) Dopamine-PEG-N3 (MW 2000) can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials Dopamine-PEG-N3 (MW 2000) is a click chemistry reagent It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group
Cayman Chemical dPE-PEG 2000-CoH 10mg
A PEGylated derivative of DSPE; has been used to link transferrin receptors to the surface of liposomes encapsulating doxorubicin for targeted delivery of doxorubicin in vitro and in vivo; nanomicelles containing DSPE-PEG(2000)-COOH linked to borneol and encapsulating doxorubicin reduce tumor growth and metastasis in an in situ C6 murine model of glioblastoma
eMolecules Broadpharm / m-PEG3-S-PEG1-t-butyl ester / 250mg / 303671220 / BP-23152 / 98.000 / 2365419-97-0 / MFCD29764331 / 352.490 / C16H32O6S
Broadpharm / m-PEG3-S-PEG1-t-butyl ester / 250mg / 303671220 / BP-23152 / 98.000 / 2365419-97-0 / MFCD29764331 / 352.490 / C16H32O6S