General Cell Based Assays
Revvity Health Sciences Inc HTRF mAb Anti-GST Eu-Conjugate, 20,000 Assay Points
HTRF mAb Anti-GST Eu-Conjugate, 20,000 Assay Points
Revvity Health Sciences Inc HTRF cAMP Gs HiRange Detection Kit Standard
HTRF cAMP Gs HiRange Detection Kit Standard
Eurofins Discoverx PathHunter eXpress mCXCR4 U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0481E3MCP5L)
The PathHunter mCXCR4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CXCL12/SDF-1α) based activation of mCXCR4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCXCR4 and EA-tagged β-Arrestin-2. Activation of mCXCR4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human IL-9 (IL9R/IL2RG) Dimerization Cell-Based Assay Kit (HEK 293)
The PathHunter Human IL-9 (IL9R/IL2RG) Stable Cell Line Dimerization Assay (HEK 293) measures ligand-induced dimerization of IL9R/IL2RG. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human RXRα Nuclear Receptor Protein Interaction Cell-Based Assay Kit (U2OS)
The PathHunter Human RXRα Nuclear Receptor Stable Cell Line Protein Interaction Assay (U2OS) contains a stable clonal cell line used to measure activated RXRα nuclear hormone receptor interaction with SRCPs. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cayman Chemical RXR RetInoId X receptr100uL
An inhibitor of PI3K and PI3KY (IC50s 24.5 and 33.2 nM respectively) greater than 300- and 120-fold selective for PI3K and PI3KY respectively over PI3Ka and PI3KB induces cell death in L-540 KM-H2 and L-428 cells at 10 UM induces cell cycle arrest at the G0/G1 phase in the same cells reduces tumor growth and vasculature induces tumor necrosis and induces the M1 phenotype in TAMs in an L-540 mouse xenograft model
Meso Scale Discovery RPLEX HUM Cathepsin L2 ASYQP
The R-PLEX Human Cathepsin L2 Assay is a multiplex immunoassay kit from Meso Scale Diagnostics that allows for the quantitative measurement of human Cathepsin L2 in serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample volume requirements This assay kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an ECL tag calibrators and diluents needed to perform the assay It can detect Cathepsin L2 concentrations as low as 3 2 pg/mL with an upper limit of 100 000 pg/mL
Meso Scale Discovery R-PLEX Human GFAP ASY
The R-PLEX Human GFAP Assay Kit from Meso Scale Discovery measures glial fibrillary acidic protein (GFAP) in human samples using electrochemiluminescence (ECL) technology It offers high sensitivity a wide dynamic range and low sample volume requirements The kit includes a 96-well plate with capture and detection antibodies Read Buffer Sample Diluent and calibrators for standard curve generation It quantifies GFAP a biomarker in astrocytes linked to CNS disorders with a 2 5-hour protocol for high-throughput profiling
Eurofins Discoverx PathHunter Human FGR Kinase Activity Cell-Based Assay Kit (U2OS)
The PathHunter Human FGR Stable Cell Line Kinase Activity Assay (U2OS) measures FGR CTK activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Miltenyi Biotec, Inc. RNAsky™ Support Kit
Contains support reagents and mixing vials required for running the RNAsky assay with the MACSima System.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
Innovative Research Inc Hmn uPA Rcmb LMW 1mg
Human Urokinase (uPA) Recombinant Low Molecular Weight 1mg - Human Urokinase (uPA) Recombinant Low Molecular Weight from Innovative Research has been recombinantly produced in insect cells and purified using a combination of conventional and affinity chromatography. This is a frozen liquid buffered in 0.05M Sodium Acetate; 0.1M NaCl; 1mM EDTA; pH 5.0 and a purity of 95%. It is useful as a positive control for ELISA and western blot and and other applications including cell differentiation, cell signaling, clotting assays, fibrinolysis, plasminogen activation, protein-protein interactions, receptor binding, thromboelastography, and thrombolysis. Purified from auto-catalytic digestion of recombinant human urokinase produced in insect cells. Active two-chain low molecular weight human urokinase contains the proteinase domain and is separated from the amino terminal fragment by cleavage at the Lys135-Lys136 bond.
Eurofins Discoverx PathHunter eXpress MC4R U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0211E3CP0M)
The PathHunter MC4R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. α-MSH) based activation of MC4R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MC4R and EA-tagged β-Arrestin-2. Activation of MC4R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ABclonal Technology β-Actin Rabbit pAb
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome.
Eurofins Discoverx PathHunter eXpress TACR2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0238E2CP0M)
The PathHunter TACR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. substance P) based activation of TACR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged TACR2 and EA-tagged β-Arrestin-2. Activation of TACR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress CALCRL-RAMP3 CHO-K1 GPCR Assay, 10-plate Kit. (95-0169E2CP2L)
The cAMP Hunter CALCRL-RAMP3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. adrenomedullin) based activation of CALCRL (paired with RAMP3) GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CALCRL, a naturally Gs coupled GPCR, alongside modulator protein RAMP3. Upon activation of CALCRL, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.