Protein Purification
MilliporeSigma™ Calbiochem™ Bufalin
A cardiotonic steroid isolated from toads of Bufo species that potently inhibits ouabain-sensitive Na+,K+-ATPase activity (IC50 = 1.4 nM).
MilliporeSigma™ Calbiochem™ AY 9944
A cell-permeable amphiphilic diamine that blocks cholesterol biosynthesis and its esterification.
MilliporeSigma™ Calbiochem™ 2-APB
A cell-permeable modulator of Ins(1,4,5)P3-induced Ca2+ release.
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MilliporeSigma™ Calbiochem™ Elastase Inhibitor V
A benzoxazinone compound that acts as a potent inhibitor of human leukocyte elastase (IC50 =
MilliporeSigma™ Calbiochem™ NF-κB Activation Inhibitor
The NF-κB Activation Inhibitor, also referenced under CAS 545380-34-5, controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ Nitric Oxide Synthase, Neuronal Inhibitor I
The Nitric Oxide Synthase, Neuronal Inhibitor I, also referenced under CAS 357965-99-2, controls the biological activity of neuronal Nitric Oxide Synthase. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ Nrf2 Activator III, TAT-14 Peptide
The Nrf2 Activator III, TAT-14 Peptide modulates the biological activity of Nrf2. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ LRRK2 Inhibitor III, HG-10-102-01
A cell-permeable 2,4-diaminopyrimidinyl compound that acts as a potent, ATP-competitive LRRK2-selective inhibitor (IC5050 =
MilliporeSigma™ Calbiochem™ β-Secretase Substrate IV, Fluorogenic
β-Secretase Substrate IV, Fluorogenic, is a highly sensitive FRET substrate. Hydrolysis of the substrate (Leu-Asp cleavage) by β-secretase results in fluorescence enhancement.
MilliporeSigma™ Calbiochem™ Wnt/β-catenin Inhibitor, Cardamonin
The Wnt/β-catenin Inhibitor, Cardamonin, also referenced under CAS 19309-14-9, controls the biological activity of Wnt/β-catenin. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ L-(–)-Epinephrine-(+)-bitartrate
α,β-Adrenergic receptor agonist.
MilliporeSigma™ Calbiochem™ Caspase-2 Inhibitor I
The Caspase-2 Inhibitor I controls the biological activity of Caspase-2. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Kainic Acid
An excitatory amino acid receptor agonist selective for the kainate receptor subtype (Ki = 21nM for 3H-kainate binding in rat striatum).
MilliporeSigma™ Calbiochem™ Mitochondrial Division Inhibitor, mdivi-1
The Mitochondrial Division Inhibitor, mdivi-1, also referenced under CAS 338967-87-6, controls the biological activity of yeast Dnm1 and mammalian Drp1.
MilliporeSigma™ Calbiochem™ TOFA
A cell-permeable furoic acid compound that acts as a potent, reversible, and competitive inhibitor of acetyl-CoA carboxylase (ACC), a key enzyme involved in the fatty acid biosynthesis.