Protein Purification
MilliporeSigma™ Calbiochem™ mGlu7 Antagonist, XAP044
A blood-brain barrier permeable, potent, selective, and reversible antagonist of mGlu7 receptor (IC50 = 3.5 and 2.8 μM for mGlu7a and mGlu7b in CHO cells).
MilliporeSigma™ Calbiochem™ SB 202190, Hydrochloride
A water-soluble form of the potent p38 MAP kinase inhibitor SB 202190.
MilliporeSigma™ Calbiochem™ PP2
PP2, CAS 172889-27-9, is a potent, reversible, ATP-competitive, inhibitor of the Src family of protein tyrosine kinases (IC50 = 4, 5, 5, & 100 nM for p56lck, p59fynT, Hck, & Src, respectively).
Novus Biologicals™ Vismodegib Hedgehog inhibitor
May be dissolved in DMSO (200 mg/mL); or ethanol (10 mg/mL, warm)
MilliporeSigma™ Calbiochem™ Calmodulin Kinase IINtide
A potent and specific inhibitor of CaMK II (IC50 = 50 nM for both the total and Ca2+-independent CaMK II activity).
MilliporeSigma™ Calbiochem™ AKR1C1 Inhibitor, 5-PBSA
The AKR1C1 Inhibitor, 5-PBSA, also referenced under CAS 4906-68-7, controls the biological activity of AKR1C1.
MilliporeSigma™ Calbiochem™ JAK2 Inhibitor II
The JAK2 Inhibitor II, also referenced under CAS 1837-91-8, controls the biological activity of JAK2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Okadaic Acid, Potassium Salt
Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.
MilliporeSigma™ Calbiochem™ Cathepsin D Substrate I
Useful as a substrate for the determination of cathepsin D activity.
MilliporeSigma™ Calbiochem™ PI3Kδ Inhibitor, SW30
The PI3Kδ Inhibitor, SW30 controls the biological activity of PI3Kδ. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ ERK Activation Inhibitor Peptide II, Cell-Permeable
The ERK Activation Inhibitor Peptide II, Cell-Permeable controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ WHI-P180
A potent inhibitor of lgE-mediated mast cell responses to allergens in vitro and in vivo.
MilliporeSigma™ Calbiochem™ Akt Inhibitor V, Triciribine
The Akt Inhibitor V, Triciribine, also referenced under CAS 35943-35-2, controls the biological activity of Akt.
MilliporeSigma™ Calbiochem™ DUB Inhibitor XI
A cell-permeable compound that acts as a dual inhibitor of USP7 (IC50 = 0.42 μM) and USP47 (IC50 = 1.0 μM).
MilliporeSigma™ Calbiochem™ GSK-3 Inhibitor X
The GSK-3 Inhibitor X, also referenced under CAS 740841-15-0, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.