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A cell-permeable, potent, selective, reversible, and ATP-competitive inhibitor of TGF-β type I receptor (ALK5; IC50 = 23 nM, 4nM and 18nM for ALK5 binding, ALK5 auto-phosphorylation, and TGF-β cellular assay in HepG2 cells, respectively)
The Cathepsin G Inhibitor I, also referenced under CAS 429676-93-7, controls the biological activity of Cathepsin G. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
The InSolution™ Akt Inhibitor IV controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Use for cleanup of biomolecules with a molecular weight >5000 Mr in sample volumes up to 1mL. Cytiva Life Sciences™ PD MidiTrap™ G-25 Sample Preparation Columns are convenient and prepacked.
The Myosin Light Chain Kinase Inhibitor Peptide 18 controls the biological activity of Myosin Light Chain Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
A potent proton-gated sodium channel (ASIC1a) channel blocking neurotoxin (IC50 = 0.9 nM) that can distinguish between the two ASIC1 splice variants, ASIC1a and ASIC1b.
The Wnt/β-catenin Inhibitor, Cardamonin, also referenced under CAS 19309-14-9, controls the biological activity of Wnt/β-catenin. This small molecule/inhibitor is primarily used for Cancer applications.