Protein Purification
MilliporeSigma™ Calbiochem™ P2Y Antagonist II, BPTU
A phenoxypyridinyl-phenylurea that acts as a highly selective P2Y1 antagonist (Ki = 6nM against 0.5nM 2-MeS-ADP for hu
MilliporeSigma™ Calbiochem™ Wnt Synergist, QS11
A cell-permeable purine compound that binds ARFGAPs (Kd = 364 and 620 nM for AMAP1 and ARFGAP1, respectively) and acts as a broad specificity ARFGAPs inhibitor (GTPase activating proteins of ADP-ribosylation factor).
MilliporeSigma™ Calbiochem™ cFMS Receptor Inhibitor IV
The cFMS Receptor Inhibitor IV, also referenced under CAS 959626-45-0, controls the biological activity of cFMS. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ NS309
A potent activator of Ca2+ -activated K+ channels of SK and IK types, but not BK type channels. It is at least 1000 times more potent than 1-EBIO.
MilliporeSigma™ Calbiochem™ Bax-Inhibiting Peptide, Negative Control
A cell-permeable negative control of the Bax-Inhibiting Peptide, V5. Does not suppress Bax-mediated apoptosis (≈200 μM).
MilliporeSigma™ Calbiochem™ PARP Inhibitor VI, NU1025
The PARP Inhibitor VI, NU1025, also referenced under CAS 90417-38-2, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Wnt Agonist I in DMSO
The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Cdk2 Inhibitor III
The Cdk2 Inhibitor III, also referenced under CAS 199986-75-9, controls the biological activity of Cdk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Pin1 Inhibitor, DTM
A cell permeable competitive inhibitor of Pin1 (EC50 = 4.1 μM, Ki = 50 nM).
MilliporeSigma™ Calbiochem™ SU6656
A potent, cell-permeable, reversible, and ATP-competitive Src family kinase inhibitor.
MilliporeSigma™ Calbiochem™ Heat Shock Protein Inhibitor I
Heat Shock Protein Inhibitor I, CAS 218924-25-5 blocks the induction of HSP70, HSP72, and HSP105. Blocks the development of thermotolerance in a dose-dependent manner.
MilliporeSigma™ Calbiochem™ Carbonic Anhydrase IX/XII Inhibitor II, U-104
The Carbonic Anhydrase IX/XII Inhibitr II, U-104 controls the biological activity of Carbonic Anhydrase IX/XII. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Forskolin, Coleus forskohlii
Forskolin, CAS 66575-29-9, is a cell-permeable diterpene inotropic agent that acts as an activator of adenylate cyclase (EC50 = 4 mM).
MilliporeSigma™ Calbiochem™ InSolution™ Glutaminase Inhibitor, Compound 968
A cell-permeable benzophenanthridinone compound that acts as an allosteric and reversible inhibitor of mitochondrial glutaminase activity and represses the growth and invasive activity in glutaminase upregulated fibroblasts and in tumor cells (IC50 ≤ 10μM in NIH3T3 cells stably expressing Dbl, Cdc42-F28L, Rac-F28L or RhoC-F30L mutants and in SKBR3 and MDA-MB231 cancer cel
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MilliporeSigma™ Calbiochem™ Caspase-9 Inhibitor II, Cell-Permeable
The Caspase-9 Inhibitor II, Cell-Permeable controls the biological activity of Caspase-9. This small molecule/inhibitor is primarily used for Cancer applications.