Protein Purification
MilliporeSigma™ Calbiochem™ TSPO Agonist, Ro5-4864
A 4'-chloro derivative of diazepam that lacks affinity for GABA-A receptors, but can serve as a ligand for the peripheral benzodiazepine receptor.
R&D Systems™ Glycosyltransferase Activity Kit
A simple, nonradioactive, high throughput-compatible format for assaying the enzyme activity of glycosyltransferases that use diphosphonucleotide sugars as donor substrates
MilliporeSigma™ Calbiochem™ Adenovirus Proteinase Inhibitor, NSC 37249
An inhibitor of adenovirus cysteine proteinase AVP that simultaneously targets AVP co-factor pVIc N-terminal binding pocket (K
MilliporeSigma™ Calbiochem™ Kir6.2/SUR1 Channel Activator, VU0071063
A fast acting, reversible, and selective activator of Kir6.2/SUR1 channels (EC50 = 7 μM).
MilliporeSigma™ Calbiochem™ Lenaldekar (LDK)
An inhibitor of T cell proliferation (IC50 = 3 μM in CD3+, CD4+, and CD8+ cells). Does not affect other cell types.
MilliporeSigma™ Calbiochem™ Glucokinase Activator III, Ro-28-1675
A cell-permeable activator of glucokinase. Exhibits in vivo glucose-lowering and insulin-releasing activity
MilliporeSigma™ Calbiochem™ SHIP2 Inhibitor II, CPDA
A cell-permeable aminopyridine acetamide based compound that acts as an inhibitor of SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2) that can overcome insulin resistance in 3T3-L1 adipocytes.
MilliporeSigma™ Calbiochem™ BMX/BTK Inhibitor II, QL47
A cell-permeable, highly potent, selective, irreversible inhibitor of BTK (IC50 = 6.6 nM).
MilliporeSigma™ Calbiochem™ InSolution™ TAPI-2
A 10 mM (1 mg/241 μL) sterile-filtered solution of TAPI-2 in H2O.
MilliporeSigma™ Calbiochem™ Opn4 Antagonist
Prevents melanopsin/Opn4 photoactivation in a reversible manner. Inhibits cellular phototransduction mediated by human Opn4 (IC50 = 665 nM; using CHO transfectants).
Grazoprevir, Thermo Scientific™
MilliporeSigma™ Calbiochem™ S1P Receptor 2 Agonist, CYM-5520
A potent, selective, allosteric agonist of sphingosine-1-phosphate receptor 2 (S1PR2; EC50 = 480 nM).
MilliporeSigma™ Calbiochem™ Cdc42/Rac1 Dual Inhibitor, AZA1
A cell-permeable compound that suppresses upregulation of GTP-bound Rac1 and Cdc42. Inhibits prostate cancer cells migration by decreasing cellular F-/G-actin ratio.
MilliporeSigma™ Calbiochem™ Adenosine A3 Receptor Agonist, 2-Cl-IB-MECA
A highly selective agonist of adenosine A3 receptor (Ki = 330 pM).
MilliporeSigma™ Calbiochem™ NS309
A potent activator of Ca2+ -activated K+ channels of SK and IK types, but not BK type channels. It is at least 1000 times more potent than 1-EBIO.