Protein Purification
Electron Microscopy Sciences Substrate of Silver Coated 4" Silicon Wafer, P-Type <100>, 100 mm
EMS offers a variety of economically priced coated substrates. All coatings are deposited under vacuum using electron beam evaporation. These high quality substrates are coated with 500 Angstroms (50 nm) of silver, with a thin titanium adhesion layer (2-7 nm) between the glass and silver coating. All substrates are pre-cleaned using an ion source for quality assurance. Autoclavable. P-Type <100> wafer.
Dimensions: 100 mm
Material: Silicon Wafer P/Boron
Cayman Chemical FTase InhIbItr I 500ug
A potent and selective FTase inhibitor (IC50 = 21 nM); greater than 30-fold selective for FTase over GGTase (IC50 = 790 nM); prevents farnesylation of Ras; inhibits proliferation of cells transformed by Ras farnesylation; reduces GTP-Ras, decreases angiographic vasospasm, and improves clinical scores in a dog model of subarachnoid hemorrhage
Medchemexpress LLC Brm/Brg1 ATP inhibitor-2 | 2368900-77-8 | 99.7% | C20H20N4O2S2 | 10MG
BRM/BRG1 ATP Inhibitor-2 is a small-molecule inhibitor of the BRG1 and BRM ATPase subunits of the BAF (SWI/SNF) chromatin remodeling complex. It is supplied for research use to support studies of BAF-related disorders and investigations into epigenetic regulation and chromatin dynamics.
- Small-molecule BRG1/BRM ATPase inhibitor for studies of chromatin remodeling.
- 99.7% purity.
- White to off-white solid appearance.
- Molecular formula C20H20N4O2S2; molecular weight 412.53.
- Storage: powder -20°C for up to 3 years; in solvent -80°C for 6 months or -20°C for 1 month.
- Intended for research use only; not for human or clinical use.
- Available in multiple pack sizes suitable for screening and synthesis workflows.
Biotium CD66, pan (CEA)(Cocktail), CF568 conjugate, 0.1mg/mL
This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA positive) from pleural mesotheliomas (rarely or weakly CEA positive). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.Primary antibodies are available purified, or with a selection of fluorescent CF
Medchemexpress LLC HY-K0021 1 mL × 100 Medchemexpress, Phosphatase Inhibitor Cocktail I (100X in DMSO) CAS: Purity:>98%
Medchemexpress, HY-K0021 1 mL × 100 Phosphatase Inhibitor Cocktail I (100X in DMSO) CAS: Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-121087 5mg Medchemexpress, BCI-215 CAS:1245792-67-9 Purity:>98%
Medchemexpress, HY-121087 5mg BCI-215 CAS:1245792-67-9 BCI-215 is a potent and tumor cell-selective dual specificity MAPK phosphatase (DUSP-MKP) inhibitor. BCI-215 has cytotoxicity for tumor cells but not normal cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Asunaprevir | 630420-16-5 | MFCD27987900 | 10 mm/mL
Asunaprevir | Purity: 99.74% | Mol Wt: 748.293 | 630420-16-5 | MFCD27987900 | 10 mm/mL
American Research Products Inc Mouse Serine protease HTRA1 H
Mouse Serine protease HTRA1 (HTRA1) ELISA kit from CUSABIO Detection Range 78 pg/mL-5000 pg/mL Sensitivity 19 5 pg/mL Sample serum plasma tissue homogenates Method Sandwich
Cayman Chemical ENPP1 Inhibitor 4e, Purity: ≥98%, 50 mg
An ENPP1 inhibitor (IC50 = 0.188 µM); inhibits ENPP1 in MDA-MB-231 cells (IC50 = 0.732 µM); selectively cytotoxic to 4T1 murine metastatic breast cancer cells (IC50 = 2.99 µM) over non-cancerous L-02 and 293T cells at 50 µM; increases serum levels of IFN-β in mice when administered at a dose of 0.5 mg/kg in combination with cGAMP
Cayman Chemical Prostaglandin D2 Inhibitor, Purity: ≥98%, CAS: 885066-67-1, 25 mg
A PGD2 receptor antagonist (DP; IC50 = 0.3 nM); inhibits PGD2-induced cAMP accumulation in LS 174T cells that endogenously express the DP receptor
Cayman Chemical Ferroptosis Inhibitor D1, Purity: ≥98%, 1 mg
A free radical scavenger and an inhibitor of ferroptosis; scavenges 41.27% of DPPH radicals in a cell-free assay at 0.4 µM; inhibits erastin-induced lipid peroxidation in HT-1080 cells at 0.5 µM and erastin-induced ferroptosis in the same cells (IC50 = 22 nM); reduces infarct volume and improves neurological deficits in a mouse model of transient MCAO-induced ischemic brain injury at 5 mg/kg
Cayman Chemical Bisubstrate Inhibitor 78, Purity: ≥98%, CAS: 2368247-39-4, 1 mg
An NNMT inhibitor (IC50 = 1.41 µM); binds the NNMT active site in the binding pockets for SAM and nicotinamide; selective for NNMT over NSD2 and PRMT1 (IC50s = >50 µM for both); reduces MNA levels in, and inhibits proliferation of, HSC-2 oral cancer cells at 100 µM
Cayman Chemical BIsubstrate InhIbItr 78 500ug
An NNMT inhibitor (IC50 = 1.41 µM); binds the NNMT active site in the binding pockets for SAM and nicotinamide; selective for NNMT over NSD2 and PRMT1 (IC50s = >50 µM for both); reduces MNA levels in, and inhibits proliferation of, HSC-2 oral cancer cells at 100 µM
Cayman Chemical MAGL Inhibitor Compound 23, Purity: ≥95%, CAS: 2324160-91-8, 50 mg
An inhibitor of MAGL (IC50 = 80 nM); selective for MAGL over CB1, CB2, FAAH, ABHD6, and ABHD12 (IC50s = >10 μM); inhibits the growth of HCT116, MDA-MB-231, Caov-3, OVCAR-3, and SKOV3 cells (IC50s = 21, 7.9, 25, 57, and 15 μM, respectively) but not MRC5 cells (IC50 = >100 μM); increases the levels of 2-AG in mouse brain and plasma at 50 mg/kg
Cayman Chemical PKCβ Inhibitor, Purity: ≥98%, CAS: 257879-35-9, 5 mg
A PKCβ Inhibitor (IC50s = 21 and 5 nM, respectively); selective for PKCβ1 and PKCβ2 over PKCα, PKCε, and PKCγ (IC50s = 331, 2,807, and >1,000 nM, respectively), as well as JAK1, JAK2, and TYK2 (IC50s = 770, 3,850, and 2,310 nM, respectively); inhibits JAK3 (IC50 = 17 nM); induces apoptosis and inhibits cell cycle progression in 2F7 AIDS-related Burkitt's lymphoma cells at 14 µM