Protein Purification

MilliporeSigma™ Calbiochem™ Carbonyl Cyanide m-Chlorophenylhydrazone

Protonophore. Uncoupling agent for oxidative phosphorylation that inhibits mitochondrial function. Approximately 100 times more effective than 2,4-dinitrophenol.

MilliporeSigma™ Calbiochem™ CMP-Sialic Acid, Disodium Salt InSolution™

A 25 mM (10 mg/608 μL) sterile-filtered solution of CMP-Sialic Acid, Disodium Salt in H₂O.

MilliporeSigma™ Calbiochem™ Oxymetazoline Hydrochloride

Oxymetazoline Hydrochloride is an α₂-Adrenergic receptor agonist. Enhances EGF- and PDGF-induced DNA synthesis.

MilliporeSigma™ Calbiochem™ NAE Inhibitor, MLN4924

NAE Inhibitor, MLN4924, CAS 951950-33-7, is an AMP mimetic that forms a NAE-catalyzed NEDD8 adduct, which acts as a tight-binding, ATP-competitive NAE inhibitor (IC50 = 4.7nM).

MilliporeSigma™ Calbiochem™ α,β-methylene ATP

A metabolically stable and selective P2X purinergic receptor agonist (pEC₅₀

MilliporeSigma™ Calbiochem™ Salvinorin A

A highly potent and selective non-alkaloid positive allosteric modulator of κ-opioid receptors (K_i

MilliporeSigma™ Calbiochem™ Nefazodone Hydrochloride

A potent 5-HT_2A receptor antagonist (K_d = 26nM), with moderate affinity for the alpha1-adrenergic receptor (K_d = 48nM) and 5-HT_1A receptor

MilliporeSigma™ Calbiochem™ SU1498

A potent, reversible, ATP-competitive and selective inhibitor of Flk-1 kinase (IC₅₀ = 700 nM), a vascular endothelial growth factor (VEGF) receptor kinase.

MilliporeSigma™ Calbiochem™ ErbB2 Inhibitor II

The ErbB2 Inhibitor II, also referenced under CAS 928207-02-7, controls the biological activity of ErbB2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MilliporeSigma™ Calbiochem™ CaMKII Inhibitor, CK59

The CaMKII Inhibitor, CK59, also referenced under CAS 140651-18-9, controls the biological activity of CaMKII. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Thermo Scientific™ CaptureSelect™ Alpha-1 Antitrypsin Select Leakage ELISA

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Thermo Scientific™ CaptureSelect™ Alpha-1 AntitrypsinSelect Leakage ELISA is designed to detect possible leached ligand of human Alpha-1 antitrypsin (AAT) purified using AAT Select affinity resin (Cytiva).

MilliporeSigma™ Calbiochem™ Calmodulin Kinase IINtide

A potent and specific inhibitor of CaMK II (IC₅₀ = 50 nM for both the total and Ca2+-independent CaMK II activity).

BD anti-Rat Ig, k Light Chain Magnetic Particles - DM IMag-DM, Clone: MRK-1

MilliporeSigma™ Calbiochem™ BLM Helicase Inhibitor, ML216

A cell-permeable pyridinyl-thiadiazolylurea compound that selectively blocks Bloom's syndrome protein (BLM) helicase activity of both full-length as well as truncated BLM^636-1298 forms (IC₅₀

MilliporeSigma™ Calbiochem™ RPA Inhibitor, TDRL-505

A cell-permeable compound that targets human Replication Protein A (RPA) and inhibits its DNA-binding activity (IC₅₀ 12.9 μM).