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The MMP-2 Inhibitor III, also referenced under CAS 704888-90-4, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
A cell-permeable, selective, potent, and reversible inhibitor of USP1-UAF1 deubiquitinase (IC50 = 76 nM in Ub-Rhodamine based assays). Does not disrupt USP1-UAF1 association.
The Cathepsin K Inhibitor I controls the biological activity of Cathepsin K. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
A cell-permeable compound that blocks the growth and viability of a variety of cancer cell lines (GI50 = 160 nM in NCI-60 cells), but does not affect normal cells.
Thermo Scientific™ BT-549 Control Lysate is a stimulated cell lysate that has been validated for the expression levels and phosphorylation of key targets in the TP53 signaling pathway.
The PARP Inhibitor XII, also referenced under CAS 489457-67-2, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
The JAK3 Inhibitor II, also referenced under CAS 211555-04-3, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Formulation
C14H16N4, HCl
Concentration
2.5 mg/mL
For Use With (Application)
This product is useful for activation of TLR7 and stimulation of TLR7 has been achieved with 5 to 10μL. Use in ligand activation, functional, and in vitro reported in scientific literature (PMID 25957979)
Thermo Scientific™ CaptureSelect™ Biotin Anti-IgM Conjugate consists of a 14 kDa recombinant single domain antibody fragment (VHH affinity ligand) that specifically binds to the μ chain of human, rat, and mouse IgM antibodies.
A potent, specific, cell-permeable, reversible and ATP-competitive inhibitor of protein kinase A (Ki = 56 nM) that is prepared by a chemical modification of K-252a.
A cell-permeable imidazopyridinyl-urea compound that acts as a potent inhibitor against B-RafV600E activity (IC50 = 1nM) by targeting its ATP-binding pocket and the adjacent lipophilic allosteric site accessible only when the enzyme is in its inactive DFG-out confor
The COX-1 Inhibitor, FR122047, also referenced under CAS 130717-51-0, controls the biological activity of COX-1. This small molecule/inhibitor is primarily used for Cell Signaling applications.