Substrates
CPC Scientific DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS (trifluoroacetate salt) 0.5MG
TACE FRET substrate I that is derived from the cleavage sequence of pro-TNFa recognized by the TNFa-cleaving enzyme (TACE). TNFa is presumably shed from cell membranes by TNFa-cleaving enzyme (TACE). Incubation of the TACE substrate with recombinant human TACE gives a specific cleavage to restore the quenched fluorescence. The substrate is widely used to screen inhibitors of TNF-convertase.ONE-LETTER SEQUENCE: Dabcyl-LAQAVRSSSR-EDANSMOLECULAR FORMULA: C70H104N22O18S1MOLECULAR WEIGHT:1573.80STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [396716-14-6], SYNONYMS: DABCYL-TNF--EDANS (-4 to +6) (human)RESEARCH AREA: ApoptosisREFERENCES: A.J. H.Gearing et al., Nature , 370, 555 (1994); K.M. Mohler et al., Nature , 370, 218 (1994); Becker BF, et al.Biol Chem 383, 1821-6 (2002); Mohler KM, et al., Nature 370, 218-20. (1994);
Abcam Leu-AMC hydrochloride, Fluorogenic leucine aminopeptidase substrate, 100MG
MW 324.8 g/mol. Fluorogenic substrate for leucine aminopeptidase. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC H-Glu(AMC)-OH | 98516-76-8 | MFCD00038085 | 98.0% | 304.30 g/mol | C15H16N2O5 | 50 MG
H-Glu(AMC)-OH is a fluorogenic amino acid derivative used as a peptide substrate to measure aminopeptidase A enzyme activity. Enzymatic cleavage releases 7-amino-4-methylcoumarin (AMC), producing a fluorescent signal that enables quantitative fluorescence-based activity assays. Intended for research use only.
- Fluorogenic substrate for aminopeptidase A activity assays.
- Releases 7-amino-4-methylcoumarin (AMC) upon enzymatic cleavage.
- Enables quantitative fluorescence-based enzyme activity measurements.
- Available as a solid powder suitable for storage and assay preparation.
- Molecular weight 304.30 g/mol; formula C15H16N2O5.
- For research use only; not validated for medical applications.
Medchemexpress LLC HER2/CD340 protein, rat (HEK293, His) | >95.0% | 100 UG
Recombinant rat HER2/CD340 extracellular domain produced in HEK293 cells and provided as a lyophilized preparation with a C-terminal 10xHis tag. Intended for research applications including biochemical assays, antibody binding studies, and cell signaling experiments. Purity is >95% by reducing SDS-PAGE; molecular weight approximately 91 kDa. Formulated in 20 mM PB, 150 mM NaCl, pH 7.4. Store lyophilized at -20°C and aliquot for long-term storage at -20°C or -80°C after reconstitution.
- Recombinantly expressed in HEK293 cells.
- C-terminal 10xHis tag for detection and purification.
- Purity greater than 95% by reducing SDS-PAGE.
- Approximate molecular weight 91 kDa.
- Lyophilized formulation in 20 mM PB, 150 mM NaCl, pH 7.4.
- Suitable for binding assays, antibody characterization, and signaling studies.
- Recommended storage: lyophilized at -20°C; aliquot and store at -20°C or -80°C after reconstitution.
Medchemexpress LLC Her2/CD340 protein, rat (HEK293, His) | >95.0% | 5 UG
Recombinant rat HER2/CD340 protein expressed in HEK293 cells with a C-terminal His tag. Supplied as a purified ectodomain suitable for biochemical assays, antibody development, receptor binding studies, and structural or biophysical analysis. Molecular weight is approximately 91 kDa and purity is greater than 95% by reducing SDS-PAGE.
- Recombinant rat HER2 protein produced in HEK293 expression system.
- C-terminal His tag for efficient purification.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Approximate molecular weight 91 kDa.
- Suitable for biochemical assays, antibody generation, and binding studies.
- Available in small research quantities (for example, 5 μg).
Ubpbio Ub-AMC, 50UG
Ubiquitin 7-amido-4-methylcoumarin (Ub-AMC) is a sensitive fluorescence-based substrate of deubiquitinating enzymes. It is useful for monitoring deubiquitinating enzymes’ activity or screening inhibitors of deubiquitinating enzymes. The concentration of Ub-AMC used in deubiquitinating reactions is usually 0.1-1 µM. The released AMC fluorescence can be monitored using a fluorometer or plate reader with excitation and emission wavelengths at 360 nm and 460 nm, respectively.
New England Biolabs, Inc. Adenosine-5 Triphosphate (ATP) – 1 ml
Adenosine 5-Triphosphate (ATP) is nucleotide used as a substrate for many ATP-dependent enzyme systems, including protein kinases, protein phosphatases and DNA ligation.
Cayman Chemical DocosahexaenoIc ACD CYP450 O
A mixture that contains (±)7(8)-EpDPA, (±)10(11)-EpDPA, (±)13(14)-EpDPA, (±)16(17)-EpDPA, (±)19(20)-EpDPA, (±)7(8)-DiHDPA, (±)10(11)-DiHDPA, (±)13(14)-DiHDPA, (±)16(17)-DiHDPA, and (±)19(20)-DiHDPA
Apexbio Technology LLC Ac-IETD-AFC,5mg CAS# 211990-57-7
Ac-IETD-AFC is a fluorogenic substrate of caspase-8 and possesses amino aicd sequence IETD which is recognized by caspase-8-mediated proteolysis. It is also a substrate for caspase-3 processing enzyme, caspase-10, and granzyme B. Caspase activity can be quantified by fluorescent detection of free AFC at Ex. = 400 nm and Em. = 505 nm. Ac-IETD-AFC can be used to identify and quantify caspase-8 activity in apoptotic cell lysates and to study events downstream of caspase-8 activation. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC HER2/CD340 Human B 20ug | 20ug
The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics Upon activation it triggers the MEMO1-RHOA-DIAPH1 pathway inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization HER2/CD340 Protein Human (Biotinylated HEK293 His) is the recombinant human-derived Her2/CD340 protein expressed by HEK293 with C-His labeled tag