Isotopically Labeled Compounds
Medchemexpress LLC Boc-Leu-OH H2O-d3 10mg
Boc-Leu-OH H2O-d3 is the deuterium labeled Boc-Leu-OH H2O[1]
Medchemexpress LLC Tilmicosin-d3 | 2714486-61-8 | 5 MG
Tilmicosin-d3 is the deuterium labeled Tilmicosin. Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. It primarily acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis.
- Effective in treating respiratory diseases in livestock such as cattle, sheep, and pigs.
- Possesses immunomodulatory and anti-inflammatory effects.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Sigma Aldrich Fine Chemicals Biosciences Carbon 13C monoxde 18O Ga500ML
Carbon 13C monoxde 18O Ga500ML
Medchemexpress LLC Anastrozole-d12 | 120512-32-5 | 99.7% | C17H7D12N5 | 1 MG
Anastrozole-d12 is the deuterium labeled Anastrozole, a potent and highly selective aromatase inhibitor. It inhibits human placental aromatase with an IC50 of 15 nM. This compound is intended for research use only and can serve as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuterium substitution may impact the pharmacokinetic and metabolic profiles of drugs. It appears as a white to off-white solid.
- Potent and highly selective aromatase inhibitor
- Inhibits human placental aromatase with an IC50 of 15 nM
- Deuterium labeled Anastrozole
- Can be used as a tracer for quantitative analysis
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- White to off-white solid appearance
- Deuterium substitution can affect pharmacokinetic and metabolic profiles
Medchemexpress LLC Raloxifene-d4 hydrochloride | 1188263-47-9 | 98.6% | 514.07 | 500 UG
Raloxifene-d4 hydrochloride is the deuterium labeled form of Raloxifene, a benzothiophene-derived selective estrogen receptor modulator (SERM). It exhibits estrogen-agonistic effects on bone and lipids, and estrogen-antagonistic effects on the breast and uterus. This compound is utilized in breast cancer and osteoporosis research.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Exhibits estrogen-agonistic effects on bone and lipids
- Shows estrogen-antagonistic effects on the breast and uterus
- Valuable for breast cancer and osteoporosis research
Medchemexpress LLC Nonanoic acid-d4 | 1219795-27-3 | 1 MG
Nonanoic acid-d4, also known as Pelargonic acid-d4, is a deuterium-labeled version of Nonanoic acid. Nonanoic acid is a naturally occurring saturated fatty acid composed of nine carbon atoms. This compound is known to significantly decrease bacterial translocation, boost antibacterial activity, and notably increase the production of porcine β-defensins 1 (pBD-1) and pBD-2.
- Stable isotope-labeled compound.
- Can be utilized as a tracer in various research applications.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Valuable for pharmacokinetic and metabolic studies due to the potential of deuteration to influence drug profiles.
- Significantly reduces bacterial translocation.
- Enhances antibacterial activity.
- Remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2.
Medchemexpress LLC Sitagliptin-d4 hydrochloride | 486460-32-6 | 99.2% | 447.80 | 1 MG
Sitagliptin-d4 hydrochloride is the deuterium labeled Sitagliptin hydrochloride. This compound is an orally active and highly selective DPP4 inhibitor with an IC50 value of 19 nM. It blocks the degradation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) by competing inhibition (Kᵢ = 1 nM), thereby increasing active incretin levels. It can also directly stimulate GLP-1 secretion by intestinal L cells, independent of DPP-4, by activating cAMP/PKA and ERK1/2 pathways. Sitagliptin hydrochloride shows protective effects on pancreatic islet grafts in type 1 diabetes models and can be used for studying type 1 and type 2 diabetes.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Isoformononetin-d3 | 1 MG
Isoformononetin-d3 is a deuterium-labeled derivative of Isoformononetin, an isoflavone that functions as an analog of Daidzein. Isoformononetin has been noted for its immunoprotective effects. This compound has a molecular formula of C16H9D3O4 and a molecular weight of 271.28.
- Deuterium-labeled compound
- Analog of Daidzein
- Exhibits immunoprotective effects
- Molecular formula: C16H9D3O4
- Molecular weight: 271.28
Cambridge Isotope Laboratories CHOLIC ACID (2,2,3,4,4-D5, 98%), 0.05 G, 53007-09-3
CHOLIC ACID (2,2,3,4,4-D5, 98%), 0.05 G, 53007-09-3
Cambridge Isotope Laboratories TAURODEOXYCHOLIC ACID, SODIUM SALT (2,2,4,4,11,11-D6, 98%), 5 MG
TAURODEOXYCHOLIC ACID, SODIUM SALT (2,2,4,4,11,11-D6, 98%), 5 MG
Cambridge Isotope Laboratories NITROGEN | 29817-79-6 | 1L (15N2, 98%+)
NITROGEN | 29817-79-6 | 1L (15N2, 98%+) *This item is packaged in a Breakseal Flask, one Flask per unit, and there is a fee for each Breakseal Flask. Please add part# NC1714822 to the order for the Breakseal Flask.
Cambridge Isotope Laboratories SODIUM FORMATE (D, 98%), 5 G, 3996-15-4
SODIUM FORMATE (D, 98%), 5 G, 3996-15-4
Cambridge Isotope Laboratories NITROGEN (15N2, 98%+), 1 L, 29817-79-6
NITROGEN (15N2, 98%+), 1 L, 29817-79-6. **This item is shipped in a Code C stainless steel lecture bottle. The fee for the bottle will need added to the order as a separate charge per each. Please include part# NC9763154 to the order.
Cambridge Isotope Laboratories L-CYSTEINE (15N, 98%), 0.25 G, 204523-09-1
L-CYSTEINE (15N, 98%), 0.25 G, 204523-09-1