Isotopically Labeled Compounds
Medchemexpress LLC Adenosine-d13 | 58-61-7 | 96.6% | 1 MG
Adenosine-d13 is a deuterium-labeled version of Adenosine, a widely present endogenous autacoid. It functions by activating four G protein-coupled receptors (A1, A2A, A2B, and A3), influencing various cellular physiological processes including neuronal activity, vascular function, platelet aggregation, and blood cell regulation. This compound is intended for research use only.
- Can be used as a tracer or internal standard for quantitative analysis.
- Suitable for techniques like NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes, such as deuterium, into drug molecules may impact pharmacokinetic and metabolic profiles.
Medchemexpress LLC α-terpineol-d3 | 203633-12-9 | 98.1% | 157.27 g/mol | C10H15D3O | 10 MG
α-Terpineol-d3 is the deuterium-labeled isotopologue of α-terpineol provided as a stable-isotope reference standard for analytical and research use. It is intended for use as an internal standard and tracer in mass spectrometry and isotope-labeling studies, and is supplied in research-scale quantities for analytical workflows.
- Deuterium-labeled internal standard for mass spectrometry.
- Suitable for GC-MS and LC-MS quantitative analyses.
- High chemical purity (~98.1%).
- Provided in a small package size appropriate for analytical work (10 mg).
- Useful for tracer and isotope-labeling experiments and method development.
Medchemexpress LLC D-Glucose-13C-4 | 40762-22-9 | 98.0% | 1 MG
D-Glucose-13C-4 is the 13C labeled form of D-Glucose. D-Glucose, a monosaccharide, is a significant carbohydrate in biology, serving as a carbohydrate sweetener and a crucial component of general metabolism. It also acts as a critical signaling molecule related to both cellular metabolic status and biotic and abiotic stress responses.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Pimobendan-d3 | 74150-27-9 | 99.4% | 5 MG
Pimobendan-d3 (UD-CG115-d3) is deuterium labeled Pimobendan (HY-B0204), a selective inhibitor of PDE3 with an IC50 of 0.32 μM. It is intended for research use only and not sold to patients. This compound can be used as a tracer and internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer and internal standard
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium labeled for potential impact on pharmacokinetic and metabolic profiles
- Intended for research use only
Medchemexpress LLC Sulfamethoxazole-13C6 | 1196157-90-0 | 99.9% | 1 MG
Sulfamethoxazole-13C6 is a 13C labeled Sulfamethoxazole (Ro 4-2130-13C6), which is a sulfonamide antibiotic with widespread antibacterial activity. It inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase.
- Suitable for the study of urinary tract infections (UTIs), prostatitis, and bronchitis.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Sigma Aldrich Fine Chemicals Biosciences L-Tryptophan-15N2 95 atom % 15N, 95% (CP) | 204634-20-8 | MFCD00209799 | 250MG
L-Tryptophan-15N2 95 atom % 15N, 95% (CP) | Purity: 95% (CP) | Mol Wt: 206.21 | 204634-20-8 | MFCD00209799 | 250MG
Sigma Aldrich Fine Chemicals Biosciences L-Tryptophan-13C11,15N2 >=99 atom %, >=98% (CP) | 202406-50-6 | MFCD00209800 | 100MG
L-Tryptophan-13C11,15N2 >=99 atom %, >=98% (CP) | Purity: >=98% (CP) | Mol Wt: 217.13 | 202406-50-6 | MFCD00209800 | 100MG
Medchemexpress LLC Nicotinamide-d4 | 347841-88-7 | 100.0% | 25 MG
Nicotinamide-d4 is the deuterium labeled version of Nicotinamide, a form of vitamin B3 essential for cell physiology. It facilitates NAD+ redox homeostasis, provides NAD+ as a substrate for enzymes in non-redox reactions, and acts as an inhibitor of SIRT1. This product is intended for research use only.
- Used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration can potentially influence the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Dofetilide-d4 | 1189700-56-8 | 99.3% | 500 UG
Dofetilide-d4 is a deuterium-labeled Dofetilide, a class III antiarrhythmic agent.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Guanidine-d5 hydrochloride | 108694-93-5 | 98% | 250 MG
Guanidine-d5 hydrochloride is the deuterium labeled Guanidine hydrochloride, a strong chaotrope and denaturant of proteins. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Maprotiline-d3 hydrochloride | 1329496-63-0 | 98.8% | 1 MG
Maprotiline-d3 hydrochloride is a deuterium labeled version of Maprotiline hydrochloride. It is intended for research use only and not for patient use. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules for use as tracers during drug development. Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Ospemifene-d4 | 128607-22-7 | 99.7% | 1 MG
Ospemifene-d4 is a deuterium-labeled Ospemifene. Ospemifene is a selective and orally active estrogen receptor modulator used for the prevention of osteoporosis. It has IC50 values of 827 nM for estrogen receptor α (ERα) and 1633 nM for ERβ. Additionally, Ospemifene exhibits bone-sparing, antitumor, and cholesterol-lowering effects.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Diphenhydramine-d6 hydrochloride | 1189986-72-8 | 99.3% | 5 MG
Diphenhydramine-d6 hydrochloride is the deuterium-labeled form of Diphenphenhydramine hydrochloride, a first-generation histamine H1-receptor antagonist with anti-cholinergic effects. It can cross the ovine blood-brain barrier (BBB). Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules primarily as tracers for quantitation during drug development. Deuteration, specifically, has gained attention for its potential to impact the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.