Isotopically Labeled Compounds
Sigma Aldrich Fine Chemicals Biosciences D-Glucose 6-phosphate sodium salt | 54010-71-8 | MFCD00006611 | 500 mg
D-Glucose 6-phosphate sodium salt | Purity: ≥98% | Mol Wt: 282.12 | 54010-71-8 | MFCD00006611 | 500 mg
![Revvity Health Sciences Inc Epibatidine, ([<sup>125</sup>I]-IPH), [<sup>125</sup>I]-, 10µCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00001872-502097613.JPG-250.jpg)
Revvity Health Sciences Inc Epibatidine, ([125I]-IPH), [125I]-, 10µCi
Epibatidine, ([125I]-IPH), [125I]-, 10µCi
Medchemexpress LLC Azelaic acid-d14 | 119176-67-9 | 99.86% | 5 MG
Azelaic acid-d14 is the deuterium labeled Azelaic acid. Azelaic acid is an organic compound produced by the ozonolysis of oleic acid; it is also a component of a number of hair and skin conditioners. It is for research use only and not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Acetylcholine-d4 chloride | 344298-94-8 | 99.21% | 5 MG
Acetylcholine-d4 (chloride) is the deuterium labeled Acetylcholine chloride. Acetylcholine chloride (ACh chloride) is a neurotransmitter, a potent and BBB-permeable cholinergic agonist, and a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). It also inhibits p53 mutant peptide aggregation in vitro.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes have potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Glipizide-d11 | 1189426-07-0 | MFCD08705009 | 96.4% | 1 MG
Glipizide-d11 is the deuterium-labeled form of Glipizide, a potent, orally active sulfonylurea class anti-diabetic agent. It is primarily used in type 2 diabetes mellitus research, and not for type 1. This compound acts by partially blocking ATP-sensitive potassium (KATP) channels among β cells of pancreatic islets of Langerhans.
- Deuterium labeled Glipizide
- Potent and orally active
- Used in type 2 diabetes mellitus research
- Acts on ATP-sensitive potassium (KATP) channels
- Can be used as a tracer for quantitative analysis
- Suitable as an internal standard for quantitative analysis
Medchemexpress LLC Fexofenadine-d6 | 548783-71-7 | 99.3% | 1 MG
Fexofenadine-d6 (MDL-16455-d6) is a deuterium-labeled form of Fexofenadine, which acts as an antihistamine pharmaceutical agent. This compound is intended for research use only. It can be utilized as a tracer and as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS. Deuteration, the incorporation of stable heavy isotopes into drug molecules, is used for quantitation during drug development and has shown potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Vericiguat-d3 hydrochloride | 1350653-20-1 | 99.8% | 465.86 | 1 MG
Vericiguat-d3 (BAY1021189-d3) hydrochloride is a deuterated Vericiguat with tracer functionality. Vericiguat is an orally available stimulator of guanylate cyclase.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Apalutamide-13C,d3 | 956104-40-8 | 99.9% | 481.45 | 500 UG
Apalutamide-13C,d3 is a 13C- and deuterium labeled Apalutamide, which is a potent and competitive androgen receptor antagonist. It is intended for research use only and serves as a valuable tool for quantitative analysis in drug development.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporated stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules for quantitation
- Deuteration can potentially affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Adenine-13C | 86967-48-8 | 99.1% | 50 MG
Adenine-13C is the 13C labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases found in the nucleic acid of DNA. It serves as a chemical component of both DNA and RNA. Adenine also plays a significant role in biochemistry, specifically in cellular respiration, forming both ATP and cofactors like NAD and FAD, and in protein synthesis.
- Isotope labeled for use as a tracer.
- Can be used as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development.
Medchemexpress LLC Terazosin-d8 | 1006718-20-2 | 99.2% | 1 MG
Terazosin-d8 is a deuterium labeled version of Terazosin, a quinazoline derivative and a competitive, orally active α1-adrenoceptor antagonist. It functions by relaxing blood vessels and opening the bladder, showing potential for treating benign prostatic hyperplasia (BPH) and high blood pressure. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Competitive and orally active α1-adrenoceptor antagonist
- Relaxing blood vessels and opening the bladder
- Potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment
Medchemexpress LLC Phenacetin-13C | 72156-72-0 | 99.9% | 100 MG
Phenacetin-13C is the 13C labeled Phenacetin. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent and a selective COX-3 inhibitor. It is used as a probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development
Medchemexpress LLC Thiabendazole-d4 (2-(4-thiazolyl)benzimidazole-d4) | 1190007-20-5 | 99.8% | 1 MG
Thiabendazole-d4 is a deuterated form of Thiabendazole, acting as an antiseptic, antifungal, and antiparasitic agent. This compound is primarily used as a tracer and as an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC (S)-Mirtazapine-d3 | 61337-87-9 | 99.0% | 5 MG
(S)-Mirtazapine-d3, also known as (S)-Org3770 d3 or (S)-6-Azamianserin d3, is a deuterium-labeled compound. It acts as an 5-HT2 receptor antagonist and has a purity of 99.0%. The molecular formula is C17H16D3N3 and its molecular weight is 268.37.
- Deuterium-labeled compound
- Acts as an 5-HT2 receptor antagonist
- High purity of 99.0%
- Identified by molecular formula C17H16D3N3
- Molecular weight of 268.37
Medchemexpress LLC Ethylenethiourea-d4 | 352431-28-8 | 106.18 | 1 MG
Ethylenethiourea-d4 is the deuterium labeled Ethylenethiourea. Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic, and it is orally active.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories SUBERIC ACID (2,2,7,7-D4, 98%), 1 G, 19031-57-3
SUBERIC ACID (2,2,7,7-D4, 98%), 1 G, 19031-57-3