Isotopically Labeled Compounds
Medchemexpress LLC D-ribose-d2 | 478506-32-0 | MFCD08459971 | 98.0% | 152.14 g/mol | C5H8D2O5 | 50 MG
D-Ribose-d2 is a deuterium-labeled form of D-ribose (two deuterium atoms) used as a stable isotope reagent in metabolic tracing, NMR, and analytical research. It is supplied as a white to off-white solid with high purity and is intended for use in tracer studies and structural analysis. CAS 478506-32-0; molecular weight 152.14 g/mol.
- Deuterium-labeled tracer for metabolic and flux studies.
- Suitable for NMR and mass spectrometry experiments.
- High purity for reliable analytical results.
- White to off-white solid form for easy handling.
- Stable when stored under recommended conditions.
- Offered in small research-scale quantities.
Medchemexpress LLC L-ornithine-d2 hydrochloride | 2483831-42-9 | MFCD12091013 | 99.9% | 170.63 | C5H11D2ClN2O2 | 100 MG
L-ornithine-d2 hydrochloride is the deuterium-labeled form of L-ornithine hydrochloride supplied for research use as a white to off-white solid. It is intended for use as a stable-isotope reagent in quantitative mass spectrometry, metabolic tracing, and other analytical applications, and is provided with documentation confirming identity and purity.
- Deuterium-labeled stable isotope suitable for analytical standards.
- High purity for quantitative applications (99.94%).
- White to off-white solid for convenient handling and storage.
- Supplied with a certificate of analysis for batch-specific data.
- Water soluble for preparation of aqueous stock solutions.
Medchemexpress LLC Hexamethylbenzene-d18 | 4342-40-9 | MFCD00144445 | 99.5% | 180.38 g/mol | C12D18 | 100 MG
Hexamethylbenzene-d18 is the fully deuterated analogue of hexamethylbenzene (C12D18), supplied as an isotopically enriched reference standard and synthetic intermediate for research. It is characterized by a molecular weight of 180.38 g/mol and is provided as a purified, neat material suitable for analytical, spectroscopic, and mechanistic studies.
- Fully deuterated (C12D18) for isotope labeling.
- High isotopic enrichment (~99.3% D) for tracer and mechanistic studies.
- High chemical purity (HPLC 99.47%) for analytical reliability.
- Neat, purified material suitable for use as a reference standard or synthetic intermediate.
Medchemexpress LLC 16:0-18:1 PE-d31 | 326495-44-7 | 99.8% | 749.19 | 1 MG
16:0-18:1 PE-d31 is deuterium labeled 16:0-18:1 PE. It is for research use only and not sold to patients. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 3-Hydroxychrysene-d11 | 2468771-62-0 | C18HD11O | 1 MG
3-Hydroxychrysene-d11 is the deuterium labeled 3-Hydroxychrysene. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules serves as tracers for quantitation during drug development. Deuteration, in particular, has garnered attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled 3-hydroxychrysene
- Used as a tracer
- Functions as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS applications
- Utilizes stable heavy isotopes for drug development quantitation
- Potential to influence pharmacokinetic and metabolic profiles
Medchemexpress LLC Indomethacin-d4 Methyl Ester | 1217064-61-3 | 98.4% | C20H14D4ClNO4 | 1 MG
Indomethacin-d4 Methyl Ester is a deuterium-labeled form of Indomethacin, a potent, blood-brain permeable, and nonselective inhibitor of both COX-1 and COX-2 enzymes. It demonstrates inhibitory activity with IC50s of 18 nM for human COX-1 and 26 nM for COX-2 in CHO cells. This compound has also been observed to disrupt autophagic flux by interfering with the normal function of lysosomes.
- Deuterium labeled derivative of indomethacin
- Potent and nonselective COX-1 and COX-2 inhibitor
- Blood-brain barrier permeable
- Disrupts autophagic flux through lysosomal interference
- Useful as a tracer or internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Zoledronic acid-d3 (zoledronate-d3) | 1134798-26-7 | 275.11 | 1 MG
Zoledronic acid-d3 (Zoledronate-d3) is the deuterium labeled Zoledronic acid. Zoledronic Acid (Zoledronate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid also has anti-cancer effects.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Methanol-d1 | 1455-13-6 | MFCD00044213 | 99.8% | 33.05 g·mol⁻¹ | CH3DO | 5 G
Methanol-d1 (CH3DO) is the deuterium-labeled form of methanol used as an isotopically enriched solvent and tracer in analytical and synthetic chemistry. It provides a single deuterium substitution that aids NMR spectral interpretation and isotopic labeling studies. Typical properties include CAS 1455-13-6 and a molecular weight of 33.05 g·mol⁻¹.
- High isotopic purity (reported 99.8%).
- Useful as an NMR solvent and spectral reference.
- Suitable for mass spectrometry and isotopic labeling experiments.
- Volatile, low boiling solvent-handle in a fume hood.
- Supplied in small research-scale packages (5 g) for laboratory use.
Medchemexpress LLC Drospirenone-d4 | 2376035-94-6 | 98.5% | C24H26D4O3 | 2.5 MG
Drospirenone-d4 is the deuterium labeled Drospirenone, a synthetic progestin that is an analog to spironolactone. Stable heavy isotopes are incorporated into drug molecules, primarily as tracers for quantitation during drug development. Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs. This compound is for research use only.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Doxofylline-d6 | 1219805-99-8 | >99.6% | C11H8D6N4O4 | 1 MG
Doxofylline-d6 is the deuterium labeled Doxofylline, an antagonist of the adenosine A1 receptor that also inhibits phosphodiesterase IV.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Lyso GB3-d7 | 2315262-44-1 | MFCD00036354 | ≥99.0% | 792.96 | 100 UG
Lyso GB3-d7 is deuterium labeled Lyso GB3. It is for research use only and can be used as a tracer and as an internal standard for quantitative analysis.
- Used as a tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated into drug molecules
- Deuteration can influence pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC (Rac)-Bedaquiline-d6 | 2517573-53-2 | 99.0% | 561.54 | 1 MG
(Rac)-Bedaquiline-d6 is a deuterium-labeled version of Bedaquiline that inhibits *Mycobacterium tuberculosis* F1FO-ATP synthase. It exhibits uncoupler activity and is used for multi-agent resistant tuberculosis. Deuteration can affect pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories 1 2 3-TriCN (PCN-13) (13C10 99%) 10 ug/mL in isooctane 1 2 mL
1 2 3-TriCN (PCN-13) (13C10 99%) 10 ug/mL in isooctane 1 2 mL
Cambridge Isotope Laboratories 24R 25-Dihydroxyvitamin D3 (26 26 26 27 27 27-D6 98%) 100 ug/mL in ethanol CP 97% 1 mL
24R 25-Dihydroxyvitamin D3 (26 26 26 27 27 27-D6 98%) 100 ug/mL in ethanol CP 97% 1 mL
Cambridge Isotope Laboratories EN-1948-4 PCB Sampling Standard (13C12 99%) 100 ng/mL in nonane 1 2 mL
EN-1948-4 PCB Sampling Standard (13C12 99%) 100 ng/mL in nonane 1 2 mL