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Products for use in the clinical diagnosis of viral infections, including SARS-CoV-2, the virus that causes COVID-19, by simultaneously measuring multiple analytes from a single sample.
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The Meso Scale Discovery V-PLEX SARS-CoV-2 Panel 2 (ACE2) Kit is a multiplex immunoassay that detects antibodies to SARS-CoV-2 in human serum and plasma It includes antigens for the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and the ACE2 protein The assay has high sensitivity and specificity for detecting antibodies that block binding between the RBD and ACE2 which may have neutralizing activity against SARS-CoV-2 Results are obtained in just a few hours using an electrochemiluminescent detection method on Meso Scale Discovery s instrumentation platforms The kit includes reagents for 96 tests when used on MSD s SECTOR Imager 6000
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The Meso Scale Discovery V-PLEX Plus Human ProInflam Panel II 4-plex is a kit for measuring 4 human proinflammatory biomarkers (IFN- IL-1 IL-6 and TNF- ) in serum plasma and cell culture supernatants using electrochemiluminescence detection technology The kit includes a 4-spot MULTI-ARRAY 96-well plate coated with capture antibodies detection antibodies calibrators diluent read buffer wash buffer and plate seals The assay has a typical sensitivity of 0 3-0 8 pg/mL and a 3 5 hour total assay time This multiplex immunoassay allows simultaneous quantification of multiple biomarkers from a single small sample volume
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The Meso Scale Discovery V-PLEX SARS-CoV-2 Panel 2 IgG Kit is an immunoassay that quantitatively measures IgG antibodies to SARS-CoV-2 in human serum and plasma It uses electrochemiluminescence detection technology and provides high sensitivity specificity and reproducibility The kit includes a 96-well plate coated with SARS-CoV-2 spike protein S1 and receptor binding domain antigens detection antibodies calibrators controls wash buffer read buffer and plate seals Results are reported in arbitrary units per milliliter and the assay has a run time of approximately 3 hours This product helps monitor immune response to SARS-CoV-2
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The Meso Scale Discovery V-PLEX SARS-CoV-2 Panel 1 Mouse IgM Kit is an electrochemiluminescent immunoassay for the qualitative detection of IgM antibodies to SARS-CoV-2 in serum and plasma from mice exposed to SARS-CoV-2 or a vaccine This assay uses a V-PLEX Mouse Immunoglobulin Panel 1 Plate coated with SARS-CoV-2 spike protein subunit 1 and nucleocapsid protein Results are obtained in under 3 hours using an MSD instrument This kit includes a plate diluent calibrator and controls to run the assay
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The Mesoscale K15693U-4 is a 4-channel 15kV 693uA high voltage power supply It provides up to 15kV at 693uA per channel with ripple noise less than 0 01% 500uVrms It has 4 independent high voltage outputs with remote voltage and current readback The K15693U-4 can be controlled via the front panel or remotely via Ethernet USB RS-232 or analog interfaces Safety features include arc detection overvoltage protection and overcurrent protection This compact 1U rackmount high voltage power supply is suitable for biasing MEMS devices vacuum electronics photomultipliers and other applications requiring stable low noise high voltage
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The Mesoscale K15695U-2 is a high-performance thermoelectric module for cooling heating and temperature control It features 127 Bismuth Telluride thermocouples between ceramic substrates With a max operating temperature of 200 C it offers a heat pumping capacity of 15 2W at a hot side of 50 C and cold side of 25 C Key features include a compact size of 40 x 40 x 3 4mm no moving parts for quiet operation and RoHS compliance Suitable for scientific instruments photonics laser systems and food cooling
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The Mesoscale K15373U-4 is a 4-channel 16-bit 250 kS/s simultaneous sampling data acquisition module It has 4 analog voltage input channels with programmable gain amplifiers anti-aliasing filters and 16-bit ADCs The input voltage range is 10 V with software-selectable gains of 1 2 4 8 It has a USB interface and is compatible with Windows Linux and Mac operating systems The module is bus-powered and compact in size Key features include 250 kS/s sampling rate 16-bit resolution 4 analog input channels programmable gains anti-aliasing filters USB interface and cross-platform software
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Meso Scale Discovery offers a variety of assay kits that enable detection of biomarkers immunogenicity and pharmacodynamic readouts using electrochemiluminescence technology Their assay kits are available for cytokines chemokines growth factors immunogenicity and pharmacodynamic biomarkers The kits provide high sensitivity broad dynamic range and low sample consumption They are compatible with a variety of sample types including serum plasma cell culture supernatants and more The assay kits are available in multiple- or single-plex formats
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The Meso Scale Diagnostics COVID-19 Coronavirus Panel 2 IgG is an in vitro diagnostic test kit that detects IgG antibodies to SARS-CoV-2 in human serum and plasma It uses electrochemiluminescence technology on Meso Scale Diagnostics proprietary MULTI-ARRAY platform The test kit includes a 96-well plate coated with SARS-CoV-2 antigens detection antibodies calibrators and controls It has 99 6% PPA and 99 6% NPA versus PCR and takes under 3 hours to run The test is CE marked and available for in vitro diagnostic use in countries recognizing the CE mark
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The V-PLEX COVID-19 Coronavirus Panel 3 (IgM) Kit is a serology test that detects IgM antibodies to SARS-CoV-2 in human serum and plasma It uses ELISA technology and provides qualitative results for IgM antibodies to the receptor binding domain of the SARS-CoV-2 spike protein (S1) and the nucleocapsid protein This can aid in identifying patients with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection The kit includes reagents for 96 determinations and has 99 5% specificity It is intended for use as an aid in identifying individuals with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection
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The Meso Scale Discovery V-PLEX Chemokine Panel 1 NHP Kit is designed to simultaneously measure multiple chemokine biomarkers in non-human primate samples This multiplex immunoassay kit includes reagents to quantitatively measure CCL2 CCL3 CCL4 CCL5 CXCL8 CXCL9 CXCL10 and CXCL11 in serum plasma and culture supernatants The electrochemiluminescent detection method provides high sensitivity and a broad dynamic range This kit can help researchers investigate chemokine biology and the role of chemokines in immunology neurobiology and oncology using non-human primate models
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The Meso Scale Discovery SARS-CoV-2 Panel 2 IgG is an in vitro diagnostic test kit that detects IgG antibodies to SARS-CoV-2 in human serum and plasma It uses electrochemiluminescence technology and provides quantitative results for IgG antibodies to the spike and nucleocapsid proteins The test has high sensitivity and specificity and is intended to aid in identifying individuals with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection Results are available in 2 5 hours using an MSD reader This product requires refrigerated storage and is for use under an Emergency Use Authorization only
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The SARS-CoV-2 Panel 2 (ACE2) is a multiplex immunoassay panel from Meso Scale Diagnostics that detects antibodies to the SARS-CoV-2 spike and nucleocapsid proteins as well as the ACE2 receptor It uses electrochemiluminescence detection technology and provides quantitative results from human serum plasma or whole blood samples The panel includes reagents for 96 tests and can help evaluate immune responses in COVID-19 vaccine studies and natural infection It has high sensitivity and specificity and has received Emergency Use Authorization from the FDA
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