Cell Function Reagents and Kits
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Filtered Search Results
![Medchemexpress LLC 5-chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxybenzamide | 2112809-98-8 | 98.4% | 384.83 | C16H17ClN2O5S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000226332.png-250.jpg)
Medchemexpress LLC 5-chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxybenzamide | 2112809-98-8 | 98.4% | 384.83 | C16H17ClN2O5S | 10 MG
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JC-171 is a selective NLRP3 inflammasome inhibitor that blocks LPS/ATP-induced interleukin-1β (IL-1β) release from macrophages (IC50 = 8.45 μM). It has demonstrated activity in vitro and in vivo, including reduction of disease severity in mouse EAE models, and is supplied as a high-purity research chemical.
- Selective NLRP3 inflammasome inhibitor; IC50 = 8.45 μM for LPS/ATP-induced IL-1β release in J774A.1 macrophages.
- Shown to reduce disease severity in mouse EAE models and lower Th17 cell frequency.
- High purity (98.4%); molecular weight 384.83 g·mol⁻¹; formula C16H17ClN2O5S.
- Soluble ≥ 2.08 mg/mL in recommended vehicles for in vivo dosing.
- Available in small research pack sizes, including 10 mg.
- Recommended storage: powder at -20°C; prepared solutions at -80°C to limit freeze-thaw.
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BPS Bioscience Inc JAK2 JH2 INHIBITOR ASSAY KIT
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JAK2 JH2 Pseudokinase Domain Inhibitor Screening Assay KitSize: 384 reactions
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Biolegend ATP Red
ATP Red Reactivity Human Mouse Apps FC Live cell imaging Size 1 mg
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Biotium FLUO-3 PENTAPOTASSIUM SALT 1MG
FLUO-3 PENTAPOTASSIUM SALT 1MG
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Biotium MAG-FLUO4 AM ESTER 10X50UG
MAG-FLUO4 AM ESTER 10X50UG
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System Biosciences LLC EXO CYTO-TRACER PCT-CD63-GFP
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NC2150835 EXO CYTO-TRACER PCT-CD63-GFP
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Medchemexpress LLC HY-15621A 5mg Medchemexpress, DMA (trihydrochloride) CAS:2095832-33-8 Purity:>98%
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Medchemexpress, HY-15621A 5mg DMA (trihydrochloride) CAS:2095832-33-8 DMA trihydrochloride is a fluorescent compound (λex=340 nm, λem=478 nm). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Biotium SULFORHODAMINE 101-A-BUNGAROTO
SULFORHODAMINE 101-A-BUNGAROTO
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NEOGEN ENDO-1 4-B-XYLANASE NEOCALLIMA
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High purity recombinant endo-1,4-β-Xylanase (Neocallimastix patriciarum) for use in research, biochemical enzyme assays and in vitro diagnostic analysis.
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Medchemexpress LLC 2-AMINOACRIDONE 5MG
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501872043 2-AMINOACRIDONE 5MG
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Cayman Chemical MTT Reagent Immunoassay Kit Co
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MTT Reagent Immunoassay Kit Co
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Biotium AQUAPHILE JC-1 DMSO
AQUAPHILE JC-1 DMSO
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Medchemexpress LLC FLUO-4 AM 100UG
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501871914 FLUO-4 AM 100UG
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LICOR Sapphire700™ Stain for Cell Viability Assays and In-Cell Western™ Assay Normalization (100 L)
Sapphire700 Stain is a non-specific cell stain that accumulates in both the nucleus and cytoplasm of fixed or dead cells, but not live cells. When used to stain serial dilutions of A431 cells in 96-well plates, Sapphire700 Stain displays linearity of fluorescent signal for higher cell densities, from ~50,000 to ~250,000 cells/well. Simultaneous staining of cells with Sapphire700 and DRAQ5 (Biostatus, Ltd.) Stains expands the linear range, allowing more accurate normalization of cell number across both low and high cell densities.
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Apexbio Technology LLC Calcein AM Cell Viability Assay Kit 500T
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The Calcein AM Cell Viability Assay Kit employs calcein AM a cell-permeable fluorescent probe for assessing viable cell populations Calcein AM readily crosses membranes due to its hydrophobic acetoxymethyl (AM) modification Within viable cells intracellular esterases cleave calcein AM releasing calcein a fluorescent molecule retained by healthy cells emitting green fluorescence proportional to viable cell numbers Cells lacking this enzymatic activity typically dead or compromised remain unstained This assay is commonly applied in studies evaluating cell proliferation cytotoxicity or cell survival under various experimental conditions Compared to assays such as MTT and CCK-8 the calcein AM method allows detection of smaller cell populations often down to approximately 50 cells and provides results within approximately 30 minutes after treatment
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