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A variety of media, supplemental media components, and reagents suitable for cell culture operations and processes. Products include fully prepared media as well as antibiotics, growth factors, contamination detection and removal reagents, cell dissociation reagents, and more.
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Biapenem is a carbapenem-class antibacterial agent provided as an analytical standard for research and analytical applications. It exhibits broad-spectrum activity and is supplied with specified purity and characterization for use in assays, method development, and reference standards.
Carbapenem-class antibacterial agent with broad-spectrum activity.
Intended for research and analytical applications.
Purity 98.0%.
Chemical formula C15H18N4O4S and molecular weight 350.39 g/mol.
Provided as a small-format analytical standard suitable for assay and reference use.
CAS number 120410-24-4 for unambiguous identification.
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A p300 and CBP inhibitor binds to the p300 and CBP bromodomains (Kds 167 and 151 nM respectively) selective for p300 and CBP over BRD4 as well as a panel of 104 nuclear receptors and ion channels and a panel of 32 enzymes at 10 UM displaces acetylated histones from CBP in a cell-free assay (IC50 170 nM) reduces colony formation and increases differentiation of primary murine leukemic blasts and delays disease initiation following leukemic blast transplantation into sub-lethally irradiated mice when used at concentrations of 5 and 10 UM
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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Neutral Dissociator, pH 7.0 Two reagents are provided to dissociate your antigen-antibody complex in a column. Dialyze to desalt after dissociating under denaturing conditions with neutral dissociator.
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A-381393 is a potent, selective, brain-penetrant dopamine D4 receptor antagonist for research use in studies of dopaminergic signaling and neuronal pathways.
Potent dopamine D4 antagonism with low-nanomolar Ki values (≈1.5-1.9 nM) against human D4 subtypes.
High selectivity with >2,700-fold selectivity over D1, D2, D3, and D5 receptors.
Moderate affinity at 5-HT2A (Ki ≈370 nM), useful for selectivity profiling.
High reported purity (99.92%) and supplied in solid and DMSO solution formats.
Good DMSO solubility (≈51.7 mg/mL) and documented in vivo formulation protocols.
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TPST1 (tyrosyl protein sulfotransferase 1) catalyzes the O-sulfation of tyrosine residues located within the acidic motifs of polypeptides utilizing 3 -phosphoadenylate sulfate (PAPS) as a co-substrate This enzymatic activity plays a crucial role in post-translational modification processes especially sulfation which contributes to the structural and functional diversity of proteins TPST1 Protein Human (HEK293 His) is the recombinant human-derived TPST1 expressed by HEK293 with N-His labeled tag
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HPRG protein is a multifunctional plasma glycoprotein with the ability to bind multiple ligands including heme heparin thrombospondin etc HPRG regulates immune processes angiogenesis coagulation and fibrinolysis through zinc-dependent binding to heparin and glycosaminoglycans HPRG Protein Human (HEK293 His) is the recombinant human-derived HPRG protein expressed by HEK293 with C-His C-10 His labeled tag
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IRAK4-IN-4 is a research-grade small-molecule inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) that also inhibits cyclic GMP-AMP synthase (cGAS). It demonstrates potent biochemical activity (IRAK4 IC50 = 2.8 nM; cGAS IC50 = 2.1 nM) and is intended for preclinical research into innate immunity and inflammatory pathways. Chemical formula C22H16N2O2; molecular weight 340.37 g/mol.
Potent IRAK4 inhibition (IC50 = 2.8 nM).
Also inhibits cGAS (IC50 = 2.1 nM).
Chemical formula C22H16N2O2 and molecular weight 340.37 g/mol.
High purity, approx. 99.6%.
Suitable for in vitro and preclinical research applications.
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Anhydrotetracycline hydrochloride is a tetracycline-family antibiotic supplied as an analytical reference standard for laboratory research. It is commonly used as an effector in tetracycline-regulated gene expression systems and for analytical method development. The material is provided as the hydrochloride salt with molecular weight 462.88 g·mol⁻1 and chemical formula C22H23ClN2O7.
Reference standard for research and analytical applications.
Acts as an effector in tetracycline-regulated gene expression systems.
Supplied as a hydrochloride salt; formula C22H23ClN2O7 and MW 462.88 g·mol⁻1.
High reported purity (≥98%) suitable for analytical work.
Available in small laboratory pack sizes (e.g., 10 MG, 50 MG).
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Recombinant human ubiquitin carboxyl-terminal hydrolase 10 (USP10) is a full-length deubiquitinating enzyme expressed in Sf9 insect cells and supplied with His and GST affinity tags. The protein is delivered as a filtered solution in HEPES/NaCl/glycerol/DTT buffer, intended for research use and stored frozen to preserve activity.
Full-length mature human protein (A2-L798).
Expressed in Sf9 insect cells for eukaryotic folding.
N-terminal His and GST tags for affinity purification.
Approximate molecular weight 114.7 kDa.
Purity >85.0% by reducing SDS-PAGE.
Supplied in 50 mM HEPES, 200 mM NaCl, 20% glycerol, 1 mM DTT, pH 7.5.
Store at -80°C and avoid repeated freeze-thaw cycles.
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TGFB1 proprotein is the precursor of latency-associated peptide (LAP) and active transforming growth factor Beta-1 (TGF- -1) chain which maintains TGF- -1 latency in the extracellular matrix TGFB1 binds non-covalently to TGF- -1 and interacts with environmental molecules (LTBP1 LRRC32/GARP LRRC33/NRROS) to regulate TGF- -1 activation TGF beta 1/TGFB1 Protein Canine (HEK293 His) is the recombinant canine-derived TGF beta 1/TGFB1 protein expressed by HEK293 with C-His labeled tag
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