Cell Culture Media, Supplements, and Reagents
Selleck Chemical LLC Tanespimycin (17-AAG) 10mM/1mL 75747-14-7 CP127374, NSC-330507, KOS 953
Tanespimycin (17-AAG, CP127374, NSC-330507, KOS 953) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Tanespimycin (17-AAG) induces apoptosis, necrosis, autophagy and mitophagy. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC RTI-7470-44 (hTAAR1 Antagonist) | 825658-63-7 | 99.9% | 449.84 | 50 MG
RTI-7470-44 is a potent, selective, and blood-brain barrier (BBB) penetrant human trace amine-associated receptor subtype 1 (hTAAR1) antagonist. It exhibits moderate metabolic stability and a favorable preliminary off-target profile, capable of increasing the spontaneous firing rate of mouse ventral tegmental area (VTA) dopaminergic neurons. It can be utilized for research into schizophrenia, agent addiction, and Parkinson's disease (PD).
- Potent, selective, and BBB penetrant hTAAR1 antagonist
- IC50 value of 8.4 nM and Ki value of 0.3 nM for human TAAR1
- Moderate metabolic stability
- Favorable preliminary off-target profile
- Increases spontaneous firing rate of VTA dopaminergic neurons
- Suitable for research into schizophrenia, agent addiction, and Parkinson's disease
Medchemexpress LLC Vortioxetine (hydrobromide) | 960203-27-4 | C18H23BrN2S | 200 MG
Vortioxetine hydrobromide is an antagonist of 5-HT3A and 5-HT7 receptors and an inhibitor of the 5-hydroxytryptamine transporter (SERT). It also acts as a 5-HT1A agonist and a partial 5-HT1B agonist. This compound is intended for research use only.
- Antagonist of 5-HT3A and 5-HT7 receptors
- Inhibitor of 5-hydroxytryptamine transporter (SERT)
- 5-HT1A agonist
- Partial 5-HT1B agonist
- Intended for research use only
Medchemexpress LLC Oligomycin A | 579-13-5 | 99.91% | 791.06 | 100 MG
Oligomycin A (MCH 32), produced by Streptomyces, functions as a mitochondrial F0F1-ATPase inhibitor with a Ki of 1 μM. It also demonstrates anti-fungal activity. For research use only; not sold to patients.
- Acts as a mitochondrial F0F1-ATPase inhibitor (Ki: 1 μM).
- Exhibits anti-fungal activity.
- Shows cytotoxic effects on NCI-60 cell lines with a GI50 of 10 nM.
- Inhibits the activity of Triton X-100-solubilized ATPase with a Ki of 0.1 μM.
- Inhibits the ability of spermatozoa to achieve feasible in vitro capacitation (IVC) at 2.4 μM.
- Suppresses progesterone-induced in vitro acrosome exocytosis (IVAE) and associated O2 consumption and ATP levels.
Selleck Chemical LLC 1-NM-PP1-5mg
1-NM-PP1 (PP1 Analog II, 1NM-PP1, analogue 9) is a potent inhibitor of Src family kinases with IC50 of 4.3 nM and 3.2 nM for v-Src-as1 and c-Fyn-as1, respectively. 1-NM-PP1 also inhibits CDK2-as1, CAMKII-as1 and c-Abl-as2 with IC50 of 5.0 nM, 8.0 nM and 120 nM, respectively.
Medchemexpress LLC Vorinostat-d5 1mg | 1132749-48-4 | 1 MG
Vorinostat-d5 is the deuterium-labeled analogue of vorinostat (suberoylanilide hydroxamic acid) supplied as a stable-isotope internal standard for quantitative NMR and mass spectrometry. It is provided as a white to off-white solid with high purity suitable for analytical tracer use.
- Deuterium-labeled internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- High purity suitable for analytical reference standards and tracer work.
- Supplied in small, milligram quantities for method development and calibration.
- Stable solid form with white to off-white appearance for easy handling and storage.
- Chemical formula C14H15D5N2O3 and molecular weight 269.35 g/mol.
Medchemexpress LLC Inarigivir ammonium | 2172788-92-8 | MFCD34578292 | 99.0% | 604.53 g/mol | C20H29N8O10PS | 10 MG
Inarigivir ammonium is a dinucleotide antiviral research compound shown to reduce HBV DNA and RNA in preclinical models. It is supplied as a white to light-yellow solid with high chemical purity for laboratory research applications.
- Dinucleotide antiviral active against hepatitis B virus.
- High purity: 99.04% (HPLC).
- Molecular weight 604.53 g/mol and formula C20H29N8O10PS.
- Solid form suitable for in vitro and preclinical studies.
- Available in small research quantities and DMSO solution formats.
Medchemexpress LLC HY-70037A 10mg Medchemexpress, Cinacalcet (hydrochloride) CAS:364782-34-3 Purity:>98%
Medchemexpress, HY-70037A 10mg Cinacalcet (hydrochloride) CAS:364782-34-3 Cinacalcet hydrochloride (AMG-073 hydrochloride) is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Ibuprofen (NSC 256857) S1638-50mg
Ibuprofen (NSC 256857 Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 M and 370 M respectively
Selleck Chemical LLC Tosufloxacin p-Toluenesulfonate Hydrate S5299-25mg
Tosufloxacin (T-3262) is a fluoroquinolone antibiotic that is used to treat susceptible infections
Selleck Chemical LLC RG108 S2821-200mg
RG108 (N-Phthalyl-L-tryptophan) is an inhibitor of DNA methyltransferase with IC50 of 115 nM in a cell-free assay does not cause trapping of covalent enzymes
Medchemexpress LLC Clindamycin | 18323-44-9 | MFCD00072005 | 10 MG
Clindamycin is an orally active, broad-spectrum bacteriostatic lincosamide antibiotic used in research to inhibit bacterial protein synthesis and to study suppression of virulence factors in Staphylococcus aureus and Plasmodium models.
- Broad-spectrum lincosamide antibiotic for research use.
- Inhibits bacterial protein synthesis.
- Suppresses virulence factor expression in Staphylococcus aureus at subinhibitory concentrations.
- Reported activity in Plasmodium research.
- Solubility: DMSO 125 mg/mL; H2O 2 mg/mL with warming and ultrasonic treatment.
- Storage: -20°C, protect from light; in solvent: -80°C (6 months) or -20°C (1 month).
- Molecular weight 424.98; molecular formula C18H33ClN2O5S.
Medchemexpress LLC HY-B1896B 5mg Medchemexpress, Piperaquine tetraphosphate tetrahydrate CAS:915967-82-7 Purity:>98%
Medchemexpress, HY-B1896B 5mg Piperaquine tetraphosphate tetrahydrate CAS:915967-82-7 Piperaquine tetraphosphate tetrahydrate is a potent anti-parasites agent, widely used in combination with other antimalarial agents [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Medchemexpress LLC L-homocysteine, S-[2-[(1-iminoethyl)amino]ethyl]-, phosphate | 438542-15-5 | 98.0% | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000232872.png-250.jpg)
Medchemexpress LLC L-homocysteine, S-[2-[(1-iminoethyl)amino]ethyl]-, phosphate | 438542-15-5 | 98.0% | 5 MG
GW274150 phosphate is the phosphate salt of a selective inducible nitric oxide synthase (iNOS) inhibitor supplied as a solid for laboratory research. It is provided at high reported purity and intended for research use only.
- Selective inhibitor of inducible nitric oxide synthase (iNOS).
- High purity (98.0%).
- Provided as a solid phosphate salt for stability and handling.
- Available in small research quantities suitable for assay development.
- For research use only; not for human or clinical use.
eMolecules Medchem Express / SB297006 / 5mg / 446258093 / HY-103361 / / 58816-69-6 / MFCD19690954 / 342.351 / C18H18N2O5
Medchem Express / SB297006 / 5mg / 446258093 / HY-103361 / / 58816-69-6 / MFCD19690954 / 342.351 / C18H18N2O5