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For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Laboratory specialty services comprise a range of services, including, but not limited to, analytical testing services for pharmaceutical, biomedical, and other life sciences laboratories.
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DiscoveryProbe Ion Channel Compound Library comprises 199 compounds with defined activities targeting various ion channels These channels include NMDA receptors P2X purinergic receptors TRPV1 channels AMPA receptors ATPases and TRP channels Selected compounds have documented biological activities validated by publications and recognized approvals by FDA EMA or other authoritative institutions Representative compounds such as channel antagonists and agonists facilitate mechanistic ion channel studies and pharmacological validation The library is optimized for high-throughput screening (HTS) and high-content screening (HCS) serving as a tool for exploring ion channel modulation mechanism determination target identification and functional assays in biomedical research
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CTS-1027 is a potent small-molecule inhibitor of matrix metalloproteinases (MMPs) with sub-nanomolar activity against MMP2 and MMP13 and strong selectivity over MMP1. It has been characterized in preclinical models for effects on hepatocyte apoptosis and fibrogenesis and is supplied for research use. The compound is a crystalline solid with high DMSO solubility and defined storage recommendations for powder and solutions.
Potent inhibition of MMP2 and MMP13 at sub-nanomolar concentrations.
Broad MMP activity including MMP12, MMP8, MMP3, and MMP14.
Greater than 1,000-fold selectivity over MMP1.
High solubility in DMSO enables concentrated stock preparation.
Stable as powder under recommended cold storage conditions.
Demonstrated activity in preclinical models of liver injury.
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Inorganic Ventures' pH 7 Standard is a 500mL certified reference material set in a water matrix for stability. This standard is Traceable to NIST and manufactured in accordance with our stringent Quality Assurance guidelines. See Certificate of Analysis for expiration. ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
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AMG-9810 is an antagonist of capsaicin activation of TRPV1 (IC50=24.5 nM) as well as activation by acid, heat, and endogenous ligands. Purity: ≥98%. Solubility: Soluble in DMSO (>25mg/ml); ethanol (20mg/ml). Long Term Storage: Ambient.
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DiscoveryProbe Ubiquitination Compound Library comprises 144 small molecules curated specifically for investigating ubiquitination signaling pathways These compounds engage targets such as proteasomes mTOR inhibitor of apoptosis proteins (IAPs) deubiquitinating enzymes (DUBs) and PI3K among others Provided either as lyophilized powders or dissolved in DMSO solutions the library facilitates studies examining enzyme modulation and ubiquitin-mediated protein regulation Representative molecules in this collection include proteasome inhibitors IAP antagonists and DUB modulators Applicable in cellular assays drug screening and target validation experiments the library supports fundamental biomedical research approved for use in laboratory settings
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DiscoveryProbe Metabolism-related Compound Library contains 493 biologically active small molecules targeting diverse cellular metabolic processes These compounds are well-characterized with documented bioactivity data from agencies including FDA and EMA approvals Designed specifically for research in cellular metabolism this library encompasses inhibitors agonists or modulators aimed at metabolically relevant targets such as dehydrogenases PPAR receptors HMG-CoA reductase IDO enzymes and heat shock proteins (HSPs) Representative compounds include PPAR agonists IDO inhibitors and known HMG-CoA reductase modulators enabling researchers to dissect metabolic pathways screen for novel drug targets and explore mechanisms underlying metabolic diseases
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 uM for hCA II. purity: 99%
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SERVALYT™ 3-10 Iso-Dalt 40 % (w/v) solution in water Iso-Dalt quality; special 2D grade to be used in 2D electrophoresis. Size - 2ML Storage Conditions - +2 °C TO +8 °C Catalog Number - 42951.04
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HR2-920-34/MembFac #34 (C10), 185 ml - 0.1 M Ammonium sulfate, 0.1 M HEPES sodium pH 7.5, 10% w/v Polyethylene glycol 4,000. Please note items from this supplier are non-returnable.
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