Laboratory Specialty Services
Apexbio Technology LLC DiscoveryProbe™ Ubiquitination Compound Library 100uL/well(10 mM solution),96 Well Deep Well Plate
DiscoveryProbe Ubiquitination Compound Library comprises 144 small molecules curated specifically for investigating ubiquitination signaling pathways These compounds engage targets such as proteasomes mTOR inhibitor of apoptosis proteins (IAPs) deubiquitinating enzymes (DUBs) and PI3K among others Provided either as lyophilized powders or dissolved in DMSO solutions the library facilitates studies examining enzyme modulation and ubiquitin-mediated protein regulation Representative molecules in this collection include proteasome inhibitors IAP antagonists and DUB modulators Applicable in cellular assays drug screening and target validation experiments the library supports fundamental biomedical research approved for use in laboratory settings
Apexbio Technology LLC SGI-1027 1020149-73-8 10mg
SGI-1027 (CAS 1020149-73-8) is a small-molecule inhibitor of DNA methyltransferases (DNMTs) exhibiting IC50 values of 12 5 M for DNMT1 8 M for DNMT3A and 7 5 M for DNMT3B It acts by competitively inhibiting the cofactor Ado-Met binding site rather than the DNA substrate site resulting in reduced DNMT activity and subsequent inhibition of DNA methylation SGI-1027 suppresses both mammalian and bacterial DNMTs affecting endogenous and recombinant forms In cancer cell models it induces demethylation of CpG islands in gene promoter regions leading to reactivation of silenced tumor suppressor genes such as P16 and TIMP3 and promotes DNMT1 degradation via the proteasome pathway SGI-1027 is utilized in epigenetics research to study DNA methylation dynamics and gene reactivation
Hampton Research HR2-944-94/Index #94 (H10), 185 ml - 0.2 M Sodium citrate tribasic dihydrate, 20% w/v Polyethylene glycol 3,350
HR2-944-94/Index #94 (H10), 185 ml - 0.2 M Sodium citrate tribasic dihydrate, 20% w/v Polyethylene glycol 3,350. Please note items from this supplier are non-returnable.
STA PHARMACEUTICAL US LLC 2'-OMe C(Ac) amidite | 1 g | CAS 199593-09-4 | MDL MFCD12912403
2'-OMe C(Ac) amidite is a Amidite reagent (Subcategory: 2'-OMe Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 199593-09-4
- MDL: MFCD12912403
- InChIKey: WNWUMIPFLOKTEZ-UAQIPLLRSA-N
- Molecular Weight: 801.877761998
- Molecular Formula: C42H52N5O9P
- Purity: ≥99%
- Container Type: 60 mL Glass (Septum)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 38.3 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@H](N2C(N=C(C=C2)NC(C)=O)=O)O[C@@H]1COC(C3=CC=C(C=C3)OC)(C4=CC=C(C=C4)OC)C5=CC=CC=C5)OC)OCCC#N)C(C)C)C
Hampton Research MEMBFAC NO01 185ML
HR2-920-01/MembFac #01 (A1), 185 ml - 0.1 M Sodium chloride, 0.1 M Sodium acetate trihydrate pH 4.6, 12% v/v (+/-)-2-Methyl-2,4-pentanediol. Please note items from this supplier are non-returnable.
Hampton Research HR2-935-06/StockOptions Sodium Citrate #06 pH 4.7, 185 ml
HR2-935-06/StockOptions Sodium Citrate #06 pH 4.7, 185 ml. Please note items from this supplier are non-returnable.
Apexbio Technology LLC DiscoveryProbe™ Anti-diabetic Compound Library 100uL/well(10 mM solution),96 Well Deep Well Plate
The DiscoveryProbe Anti-diabetic Compound Library comprises 110 small-molecule compounds including FDA-approved agents designed for diabetes-related biomedical research This collection targets metabolic regulatory pathways involved in diabetes such as dipeptidyl peptidase-4 (DPP-4) sodium-glucose co-transporter (SGLT) poly (ADP-ribose) polymerase (PARP) and ATP-sensitive potassium channels Representative compounds include metformin glibenclamide empagliflozin rosiglitazone and sitagliptin This library serves as a resource for investigating the molecular mechanisms of diabetes conducting potential therapeutic screening studies and developing novel diabetes-relevant research models
Hampton Research HR2-944-47/Index #47 (D11), 185 ml - 0.1 M BIS-TRIS pH 6.5, 28% w/v Polyethylene glycol monomethyl ether 2,000
HR2-944-47/Index #47 (D11), 185 ml - 0.1 M BIS-TRIS pH 6.5, 28% w/v Polyethylene glycol monomethyl ether 2,000. Please note items from this supplier are non-returnable.
Hampton Research NATRIX NO24 185ML
HR2-918-24/Natrix #24 (B12), 185 ml - 0.2 M Ammonium acetate, 0.01 M Calcium chloride dihydrate, 0.05 M Sodium cacodylate trihydrate pH 6.5, 10 % w/v Polyethylene glycol 4,000. Please note items from this supplier are non-returnable.
Hampton Research MEMBFAC NO20 185ML
HR2-920-20/MembFac #20 (B8), 185 ml - 0.1 M Sodium citrate tribasic dihydrate pH 5.6, 0.1 M Sodium chloride. Please note items from this supplier are non-returnable.
STA PHARMACEUTICAL US LLC 2'-OMe C(Ac) amidite | 1 g | CAS 199593-09-4 | MDL MFCD12912403
2'-OMe C(Ac) amidite is a Amidite reagent (Subcategory: 2'-OMe Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 199593-09-4
- MDL: MFCD12912403
- InChIKey: WNWUMIPFLOKTEZ-UAQIPLLRSA-N
- Molecular Weight: 801.877761998
- Molecular Formula: C42H52N5O9P
- Purity: ≥99%
- Container Type: 30 mL Glass (20-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 47.3 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@H](N2C(N=C(C=C2)NC(C)=O)=O)O[C@@H]1COC(C3=CC=C(C=C3)OC)(C4=CC=C(C=C4)OC)C5=CC=CC=C5)OC)OCCC#N)C(C)C)C
Crescent Chemical Co Inc SERVALYT™ 3-5
SERVALYT™ 3-5 40 % (w/v) solution in water SERVALYT™ Carrier Ampholytes (40 % w/v in water). Standard quality (analytical grade) for general use in IEF. Size - 10ML Storage Conditions - +2 °C TO +8 °C Catalog Number - 42903.01
Hampton Research NATRIX 2 NO47 185ML
HR2-917-47/Natrix 2 #47 (H11), 185 ml - 0.2 M Calcium chloride dihydrate, 0.05 M HEPES sodium pH 7.5, 28% v/v Polyethylene glycol 400, 0.002 M Spermine. Please note items from this supplier are non-returnable.
Hampton Research NATRIX 2 NO40 185ML
HR2-917-40/Natrix 2 #40 (H04), 185 ml - 0.08 M Potassium chloride, 0.02 M Magnesium chloride hexahydrate, 0.04 M Sodium cacodylate trihydrate pH 7.0, 50% v/v (+/-)-2-Methyl-2,4-pentanediol, 0.012 M Spermine tetrahydrochloride. Please note items from this supplier are non-returnable.