ACSL4 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA527137

Catalog No. PIPA527137

Description

Recommended positive controls: MCF-7, MDA-MB-231, NIH-3T3, JC, BCL-1. Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.

Specifications

• Antigen: ACSL4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Acsl4
• Gene Alias: 9430020A05Rik; Acs4; ACSL4; acyl-CoA synthetase 4; acyl-CoA synthetase long-chain family member 4; Arachidonate--CoA ligase; AU018108; Facl4; fatty acid Coenzyme A ligase, long chain 4; fatty acid-Coenzyme A ligase long chain 4; fatty acid-Coenzyme A ligase, long chain 4; fatty-acid-Coenzyme A ligase, long-chain 4; L MRX63; LACS 4; Lacs4; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 4; long-chain fatty-acid-Coenzyme A ligase 4; long-chain-fatty-acid--CoA ligase 4; mACS4; MRX63; MRX68
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113976, 2182, 50790
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.44 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O35547, O60488, Q9QUJ7
• Gene Symbols: Acsl4
• Immunogen: Synthetic peptide corresponding to a region within amino acids 649 and 711 of Human FACL4
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov