ACVR2B Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA596838

Catalog No. PIPA596838

Description

Immunogen sequence: EGEQDKRLHC YASWRNSSGT IELVKKGCWL DDFNCYDRQE CVATEENPQV YFCCCEGNFC NERFTHLPEA GGPEVTYEPP PTAPTLLTVL AYSLLPIGGL S; Positive Samples: U-87MG, K-562; Cellular Location: Cell membrane, Single-pass type I membrane protein

ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.

Specifications

• Antigen: ACVR2B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACVR2B
• Gene Alias: activin A receptor type 2B, activin A receptor type IIB, activin A receptor, type IIB, activin receptor IIB, activin receptor type IIB, Activin receptor type-2B, Activine receptor 2b (transmembrane serine kinase), ActRIIB, ACTR-IIB, ActRIIB type II activin receptor B, ACVR2B, HTX4, MGC116908
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 93
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry, Western Blot
• Concentration: 1.05 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
• Gene Accession No.: Q13705
• Gene Symbols: ACVR2B
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ACVR2B (NP_0010972)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov