Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

ACVRL1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5118826

Encompass

Catalog No. PIPA5118826


Add to Cart

Description

Description

Antibody detects endogenous levels of total ACVL1.

Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1, similar to other type 1 receptors, has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2. Mutations in ACVRL1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ACVRL1
Polyclonal
Unconjugated
ACVRL1
activin A receptor like type 1, activin A receptor type II-like 1, activin A receptor type IL, activin A receptor, type II-like 1, activin A receptor, type II-like kinase 1, Activin receptor like kinase 1, activin receptor-like kinase 1, activin receptor-like kinase-1, Acvrl1, Acvrlk1, AI115505, AI427544, ALK1, ALK-1, HHT, HHT2, ORW2, R3, R-3, Serine/threonine-protein kinase receptor R3, SETHKIR, SKR3, TGF-B superfamily receptor type I, TSR-I
Rabbit
Affinity chromatography
RUO
11482, 25237, 94
-20°C
Liquid
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P37023, P80203, Q61288
ACVRL1
A synthesized peptide derived from human ACVRL1(Accession P37023), corresponding to amino acid residues G211-A261.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Product Suggestions

Product Suggestions

Safety and Handling

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit